Macrophage Colony-Stimulating Factor
"Macrophage Colony-Stimulating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF is a disulfide-bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor (RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR).
| Descriptor ID |
D016173
|
| MeSH Number(s) |
D12.644.276.374.410.240.500 D12.776.395.240.500 D12.776.467.374.410.240.500 D23.529.374.410.240.500
|
| Concept/Terms |
Macrophage Colony-Stimulating Factor- Macrophage Colony-Stimulating Factor
- M-CSF
- CSF-1
- CSF-M
- Colony-Stimulating Factor 1
- Colony Stimulating Factor 1
- Colony-Stimulating Factor, Macrophage
- Colony Stimulating Factor, Macrophage
|
Below are MeSH descriptors whose meaning is more general than "Macrophage Colony-Stimulating Factor".
Below are MeSH descriptors whose meaning is more specific than "Macrophage Colony-Stimulating Factor".
This graph shows the total number of publications written about "Macrophage Colony-Stimulating Factor" by people in this website by year, and whether "Macrophage Colony-Stimulating Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 1 | 1 | 2 |
| 1996 | 2 | 0 | 2 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 2 | 2 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "Macrophage Colony-Stimulating Factor" by people in Profiles.
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Neutrophil and Macrophage Cell Surface Colony-Stimulating Factor 1 Shed by ADAM17 Drives Mouse Macrophage Proliferation in Acute and Chronic Inflammation. Mol Cell Biol. 2018 09 01; 38(17).
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Csf1r-mApple Transgene Expression and Ligand Binding In Vivo Reveal Dynamics of CSF1R Expression within the Mononuclear Phagocyte System. J Immunol. 2018 03 15; 200(6):2209-2223.
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Critical Role of Mast Cells and Peroxisome Proliferator-Activated Receptor ? in the Induction of Myeloid-Derived Suppressor Cells by Marijuana Cannabidiol In Vivo. J Immunol. 2015 Jun 01; 194(11):5211-22.
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Metabolic syndrome exacerbates inflammation and bone loss in periodontitis. J Dent Res. 2015 Feb; 94(2):362-70.
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CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth. Oncogene. 2015 Jul; 34(28):3651-61.
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M-CSF induces monocyte survival by activating NF-?B p65 phosphorylation at Ser276 via protein kinase C. PLoS One. 2011; 6(12):e28081.
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MITF and PU.1 recruit p38 MAPK and NFATc1 to target genes during osteoclast differentiation. J Biol Chem. 2007 May 25; 282(21):15921-9.
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Mechanical stimulation effects on functional end effectors in osteoblastic MG-63 cells. J Biomech. 2006; 39(8):1419-27.
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Secreted frizzled-related protein-1 inhibits RANKL-dependent osteoclast formation. J Bone Miner Res. 2004 Nov; 19(11):1873-81.
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RANKL coordinates cell cycle withdrawal and differentiation in osteoclasts through the cyclin-dependent kinase inhibitors p27KIP1 and p21CIP1. J Bone Miner Res. 2004 Aug; 19(8):1339-48.