"Cytochalasin D" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fungal metabolite that blocks cytoplasmic cleavage by blocking formation of contractile microfilament structures resulting in multinucleated cell formation, reversible inhibition of cell movement, and the induction of cellular extrusion. Additional reported effects include the inhibition of actin polymerization, DNA synthesis, sperm motility, glucose transport, thyroid secretion, and growth hormone release.
| Descriptor ID |
D015638
|
| MeSH Number(s) |
D03.633.100.473.231.450 D23.946.587.370.450
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cytochalasin D".
Below are MeSH descriptors whose meaning is more specific than "Cytochalasin D".
This graph shows the total number of publications written about "Cytochalasin D" by people in this website by year, and whether "Cytochalasin D" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cytochalasin D" by people in Profiles.
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The role of RhoA and cytoskeleton in myofibroblast transformation in hyperoxic lung fibrosis. Free Radic Biol Med. 2013 Aug; 61:26-39.
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Intact cytoskeleton is required for small G protein dependent activation of the epithelial Na+ channel. PLoS One. 2010 Jan 21; 5(1):e8827.
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Role of cytoskeletal components in stress-relaxation behavior of adherent vascular smooth muscle cells. J Biomech Eng. 2009 Apr; 131(4):041001.
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Growth and density-dependent regulation of NO synthase by the actin cytoskeleton in pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol Physiol. 2006 Jan; 290(1):L41-50.
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Mechanisms of vascular angiotensin II surface receptor regulation by epidermal growth factor. J Cell Physiol. 2004 Sep; 200(3):451-7.
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Listeria monocytogenes invasion of epithelial cells requires the MEK-1/ERK-2 mitogen-activated protein kinase pathway. Infect Immun. 1998 Mar; 66(3):1106-12.
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Cell surface changes and enzyme release during hypoxia and reoxygenation in the isolated, perfused rat liver. J Cell Biol. 1983 Sep; 97(3):778-86.