"Pimelic Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of compounds that are derivatives of heptanedioic acid with the general formula R-C7H11O4.
| Descriptor ID |
D010867
|
| MeSH Number(s) |
D02.241.081.337.699
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Pimelic Acids".
Below are MeSH descriptors whose meaning is more specific than "Pimelic Acids".
This graph shows the total number of publications written about "Pimelic Acids" by people in this website by year, and whether "Pimelic Acids" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pimelic Acids" by people in Profiles.
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Two new pimelic diphenylamide HDAC inhibitors induce sustained frataxin upregulation in cells from Friedreich's ataxia patients and in a mouse model. PLoS One. 2010 Jan 21; 5(1):e8825.
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Chemical probes identify a role for histone deacetylase 3 in Friedreich's ataxia gene silencing. Chem Biol. 2009 Sep 25; 16(9):980-9.
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Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylases. J Biol Chem. 2008 Dec 19; 283(51):35402-9.