"Spheroids, Cellular" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Spherical, heterogeneous aggregates of proliferating, quiescent, and necrotic cells in culture that retain three-dimensional architecture and tissue-specific functions. The ability to form spheroids is a characteristic trait of CULTURED TUMOR CELLS derived from solid TUMORS. Cells from normal tissues can also form spheroids. They represent an in-vitro model for studies of the biology of both normal and malignant cells. (From Bjerkvig, Spheroid Culture in Cancer Research, 1992, p4)
| Descriptor ID |
D018874
|
| MeSH Number(s) |
A11.251.800
|
| Concept/Terms |
Spheroids, Cellular- Spheroids, Cellular
- Cellular Spheroid
- Cellular Spheroids
- Spheroid, Cellular
- Multicellular Spheroids
- Multicellular Spheroid
- Spheroid, Multicellular
- Spheroids, Multicellular
|
Below are MeSH descriptors whose meaning is more general than "Spheroids, Cellular".
Below are MeSH descriptors whose meaning is more specific than "Spheroids, Cellular".
This graph shows the total number of publications written about "Spheroids, Cellular" by people in this website by year, and whether "Spheroids, Cellular" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 2 | 1 | 3 |
| 2014 | 1 | 2 | 3 |
| 2017 | 1 | 3 | 4 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Spheroids, Cellular" by people in Profiles.
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Persistent effects of pair bonding in lung cancer cell growth in monogamous Peromyscus californicus. Elife. 2021 05 07; 10.
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Generation of human colonic organoids from human pluripotent stem cells. Methods Cell Biol. 2020; 159:201-227.
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Repurposing disulfiram for cancer therapy via targeted nanotechnology through enhanced tumor mass penetration and disassembly. Acta Biomater. 2018 03 01; 68:113-124.
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MYC Inhibition Depletes Cancer Stem-like Cells in Triple-Negative Breast Cancer. Cancer Res. 2017 12 01; 77(23):6641-6650.
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A process engineering approach to increase organoid yield. Development. 2017 03 15; 144(6):1128-1136.
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Cell number per spheroid and electrical conductivity of nanowires influence the function of silicon nanowired human cardiac spheroids. Acta Biomater. 2017 03 15; 51:495-504.
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Manipulation of cellular spheroid composition and the effects on vascular tissue fusion. Acta Biomater. 2015 Feb; 13:188-98.
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KAT6A, a chromatin modifier from the 8p11-p12 amplicon is a candidate oncogene in luminal breast cancer. Neoplasia. 2014 Aug; 16(8):644-55.
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3D printing facilitated scaffold-free tissue unit fabrication. Biofabrication. 2014 Jun; 6(2):024111.
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Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1. Cancer Res. 2014 Feb 01; 74(3):738-750.