"Probenecid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
| Descriptor ID |
D011339
|
| MeSH Number(s) |
D02.065.884.625 D02.886.590.700.625
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Probenecid".
Below are MeSH descriptors whose meaning is more specific than "Probenecid".
This graph shows the total number of publications written about "Probenecid" by people in this website by year, and whether "Probenecid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Probenecid" by people in Profiles.
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Probenecid Improves Cardiac Function in Subjects with a Fontan Circulation and Augments Cardiomyocyte Calcium Homeostasis. Pediatr Cardiol. 2020 Dec; 41(8):1675-1688.
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Do short-term markers of treatment efficacy predict long-term sequelae of pelvic inflammatory disease? Am J Obstet Gynecol. 2008 Jan; 198(1):30.e1-7.
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Transport of estrone sulfate by the novel organic anion transporter Oat6 (Slc22a20). Am J Physiol Renal Physiol. 2006 Aug; 291(2):F314-21.
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Endometritis does not predict reproductive morbidity after pelvic inflammatory disease. Am J Obstet Gynecol. 2003 Jan; 188(1):141-8.
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Two kinetically-distinct components of UDP-glucuronic acid transport in rat liver endoplasmic reticulum. Biochim Biophys Acta. 1996 Sep 04; 1283(2):223-31.
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Dopaminergic effects of carbamazepine. Relationship to clinical response in affective illness. Arch Gen Psychiatry. 1986 Apr; 43(4):392-6.
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Lumbar cerebrospinal fluid homovanillic acid concentrations are higher in female than male non-human primates. Brain Res. 1985 May 20; 334(2):375-9.
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The effect of pimozide on CSF norepinephrine in schizophrenia. Am J Psychiatry. 1981 Aug; 138(8):1045-50.
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Dopamine-beta-hydroxylase in the cerebrospinal fluid of psychiatric patients. Biol Psychiatry. 1978 Dec; 13(6):685-94.