Transforming Growth Factor beta3
"Transforming Growth Factor beta3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A TGF-beta subtype that plays role in regulating epithelial-mesenchymal interaction during embryonic development. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta3 and TGF-beta3 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
| Descriptor ID |
D053782
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| MeSH Number(s) |
D12.644.276.374.687.300 D12.644.276.954.775.300 D12.776.467.374.687.300 D12.776.467.942.775.300 D23.529.942.775.300
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transforming Growth Factor beta3".
Below are MeSH descriptors whose meaning is more specific than "Transforming Growth Factor beta3".
This graph shows the total number of publications written about "Transforming Growth Factor beta3" by people in this website by year, and whether "Transforming Growth Factor beta3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
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Below are the most recent publications written about "Transforming Growth Factor beta3" by people in Profiles.
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Glycoprotein A repetitions predominant (GARP) positively regulates transforming growth factor (TGF) ?3 and is essential for mouse palatogenesis. J Biol Chem. 2017 11 03; 292(44):18091-18097.
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TGF-?1 Suppresses IL-33-Induced Mast Cell Function. J Immunol. 2017 08 01; 199(3):866-873.
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Simtuzumab treatment of advanced liver fibrosis in HIV and HCV-infected adults: results of a 6-month open-label safety trial. Liver Int. 2016 12; 36(12):1783-1792.
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Transforming Growth Factor-?3 Therapy Delays Postoperative Reossification and Improves Craniofacial Growth in Craniosynostotic Rabbits. Cleft Palate Craniofac J. 2016 03; 53(2):210-21.
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Generation of mice with a conditional allele for the transforming growth factor beta3 gene. Genesis. 2012 Jan; 50(1):59-66.
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Transforming growth factor ?, bone morphogenetic protein, and vascular endothelial growth factor mediate phenotype maturation and tissue remodeling by embryonic valve progenitor cells: relevance for heart valve tissue engineering. Tissue Eng Part A. 2010 Nov; 16(11):3375-83.
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Periostin promotes a fibroblastic lineage pathway in atrioventricular valve progenitor cells. Dev Dyn. 2009 May; 238(5):1052-63.
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Ligand-specific function of transforming growth factor beta in epithelial-mesenchymal transition in heart development. Dev Dyn. 2009 Feb; 238(2):431-42.
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Functional BMP receptor in endocardial cells is required in atrioventricular cushion mesenchymal cell formation in chick. Dev Biol. 2007 Jun 01; 306(1):179-92.