"Collagen Type IV" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-fibrillar collagen found in the structure of BASEMENT MEMBRANE. Collagen type IV molecules assemble to form a sheet-like network which is involved in maintaining the structural integrity of basement membranes. The predominant form of the protein is comprised of two alpha1(IV) subunits and one alpha2(IV) subunit, however, at least six different alpha subunits can be incorporated into the heterotrimer.
| Descriptor ID |
D024141
|
| MeSH Number(s) |
D12.776.860.300.250.400.100
|
| Concept/Terms |
Collagen Type IV- Collagen Type IV
- Type IV (Basement Membrane) Collagen
- Type IV Collagen
- Collagen, Type IV
|
Below are MeSH descriptors whose meaning is more general than "Collagen Type IV".
Below are MeSH descriptors whose meaning is more specific than "Collagen Type IV".
This graph shows the total number of publications written about "Collagen Type IV" by people in this website by year, and whether "Collagen Type IV" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2003 | 0 | 2 | 2 |
| 2005 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Collagen Type IV" by people in Profiles.
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Zonal regulation of collagen-type proteins and posttranslational modifications in prostatic benign and cancer tissues by imaging mass spectrometry. Prostate. 2020 09; 80(13):1071-1086.
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A Canstatin-Derived Peptide Provides Insight into the Role of Capillary Morphogenesis Gene 2 in Angiogenic Regulation and Matrix Uptake. ACS Chem Biol. 2020 02 21; 15(2):587-596.
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Kidney-targeted inhibition of protein kinase C-a ameliorates nephrotoxic nephritis with restoration of mitochondrial dysfunction. Kidney Int. 2018 08; 94(2):280-291.
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Human anti-a3(IV)NC1 antibody drug conjugates target glomeruli to resolve nephritis. Am J Physiol Renal Physiol. 2015 Oct 15; 309(8):F680-4.
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Age and SPARC change the extracellular matrix composition of the left ventricle. Biomed Res Int. 2014; 2014:810562.
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A human monoclonal antibody against the collagen type IV a3NC1 domain is a non-invasive optical biomarker for glomerular diseases. Kidney Int. 2013 Aug; 84(2):403-8.
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Effects of spironolactone on cerebral vessel structure in rats with sustained hypertension. Am J Hypertens. 2011 Jun; 24(6):708-15.
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Oxidized LDL immune complexes stimulate collagen IV production in mesangial cells via Fc gamma receptors I and III. Clin Immunol. 2011 Jun; 139(3):258-66.
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Modeling of human anti-GBM antibody-alpha3(IV)NC1 interactions predicts antigenic cross-linking through contact of both heavy chains with repeating epitopes on alpha3(IV)NC1. Am J Nephrol. 2009; 30(5):474-80.
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uPARAP expression during murine lung development. Gene Expr Patterns. 2008 Sep; 8(7-8):486-93.