"Ketoconazole" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients.
| Descriptor ID |
D007654
|
| MeSH Number(s) |
D03.383.606.560
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ketoconazole".
Below are MeSH descriptors whose meaning is more specific than "Ketoconazole".
This graph shows the total number of publications written about "Ketoconazole" by people in this website by year, and whether "Ketoconazole" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ketoconazole" by people in Profiles.
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A phase II clinical trial of neoadjuvant ketoconazole and docetaxel chemotherapy before radical prostatectomy in high risk patients. J Urol. 2011 Sep; 186(3):882-7.
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Malassezia and seborrheic dermatitis: etiology and treatment. J Cosmet Sci. 2006 Mar-Apr; 57(2):181-2.
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Lack of effect of ketoconazole-mediated CYP3A inhibition on sorafenib clinical pharmacokinetics. Cancer Chemother Pharmacol. 2006 May; 57(5):685-92.
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CYP3A4 is a vitamin D-24- and 25-hydroxylase: analysis of structure function by site-directed mutagenesis. J Clin Endocrinol Metab. 2005 Feb; 90(2):1210-9.
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Ketoconazole and other imidazole derivatives are potent inhibitors of peroxisomal phytanic acid alpha-oxidation. FEBS Lett. 1995 Dec 18; 377(2):213-6.
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25-Hydroxyvitamin D3-1 alpha-hydroxylase in porcine hepatic tissue: subcellular localization to both mitochondria and microsomes. Proc Natl Acad Sci U S A. 1990 Aug; 87(16):6009-13.