"Chromosome Walking" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A technique with which an unknown region of a chromosome can be explored. It is generally used to isolate a locus of interest for which no probe is available but that is known to be linked to a gene which has been identified and cloned. A fragment containing a known gene is selected and used as a probe to identify other overlapping fragments which contain the same gene. The nucleotide sequences of these fragments can then be characterized. This process continues for the length of the chromosome.
| Descriptor ID |
D016386
|
| MeSH Number(s) |
E05.393.183.250
|
| Concept/Terms |
Chromosome Walking- Chromosome Walking
- Chromosome Walkings
- Walking, Chromosome
- Walkings, Chromosome
|
Below are MeSH descriptors whose meaning is more general than "Chromosome Walking".
Below are MeSH descriptors whose meaning is more specific than "Chromosome Walking".
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Below are the most recent publications written about "Chromosome Walking" by people in Profiles.