"Glutathione Disulfide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A GLUTATHIONE dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being oxidized.
| Descriptor ID |
D019803
|
| MeSH Number(s) |
D12.644.456.448.500
|
| Concept/Terms |
Glutathione Disulfide- Glutathione Disulfide
- Disulfide, Glutathione
- GSSG
- Glutathione, Oxidized
- Oxidized Glutathione
|
Below are MeSH descriptors whose meaning is more general than "Glutathione Disulfide".
Below are MeSH descriptors whose meaning is more specific than "Glutathione Disulfide".
This graph shows the total number of publications written about "Glutathione Disulfide" by people in this website by year, and whether "Glutathione Disulfide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 3 | 0 | 3 |
| 2009 | 1 | 2 | 3 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glutathione Disulfide" by people in Profiles.
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A comparison of reversible versus irreversible protein glutathionylation. Adv Cancer Res. 2014; 122:177-98.
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S-glutathionylated serine proteinase inhibitors as plasma biomarkers in assessing response to redox-modulating drugs. Cancer Res. 2012 May 01; 72(9):2383-93.
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The glutathione disulfide mimetic NOV-002 inhibits cyclophosphamide-induced hematopoietic and immune suppression by reducing oxidative stress. Free Radic Biol Med. 2012 May 01; 52(9):1560-8.
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Apoptosis-inducing factor modulates mitochondrial oxidant stress in acetaminophen hepatotoxicity. Toxicol Sci. 2011 Aug; 122(2):598-605.
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Preclinical pharmacokinetic analysis of NOV-002, a glutathione disulfide mimetic. Biomed Pharmacother. 2010 Sep; 64(7):493-8.
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Protective effects of a glutathione disulfide mimetic (NOV-002) against cisplatin induced kidney toxicity. Biomed Pharmacother. 2010 Jan; 64(1):73-6.
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Exposure to supplemental oxygen downregulates antioxidant enzymes and increases pulmonary arterial contractility in premature lambs. Neonatology. 2009; 96(3):182-92.
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Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans. J Clin Invest. 2009 Mar; 119(3):573-81.
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Pharmacology of a mimetic of glutathione disulfide, NOV-002. Biomed Pharmacother. 2009 Feb; 63(2):75-8.
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NOV-002, a mimetic of glutathione disulfide. Expert Opin Investig Drugs. 2008 Jul; 17(7):1075-83.