"5'-Nucleotidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5.
| Descriptor ID |
D015720
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| MeSH Number(s) |
D08.811.277.352.650.600.600
|
| Concept/Terms |
5'-Nucleotidase- 5'-Nucleotidase
- 5' Nucleotidase
- 5'-Nucleotidase Phosphoribolase
- 5' Nucleotidase Phosphoribolase
- Adenylate Phosphatase
- AMP Phosphatase
- Cytidylate Phosphatase
- Ecto-5'-Nucleotidase
- Ecto 5' Nucleotidase
- IMP Nucleotidase
- CD73 Antigens
- IMPase
- Inosinate Phosphatase
- Pyrimidine 5'-Nucleotidase
- Pyrimidine 5' Nucleotidase
- Thymidine Phosphatase
- Uridylate 5'-Nucleotidase
- Uridylate 5' Nucleotidase
- Antigen, CD73
- CD73 Antigen
- Antigens, CD73
- 5'-AMP Nucleotidase
- 5' AMP Nucleotidase
- IMP Phosphatase
|
Below are MeSH descriptors whose meaning is more general than "5'-Nucleotidase".
Below are MeSH descriptors whose meaning is more specific than "5'-Nucleotidase".
This graph shows the total number of publications written about "5'-Nucleotidase" by people in this website by year, and whether "5'-Nucleotidase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "5'-Nucleotidase" by people in Profiles.
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Host surface ectonucleotidase-CD73 and the opportunistic pathogen, Porphyromonas gingivalis, cross-modulation underlies a new homeostatic mechanism for chronic bacterial survival in human epithelial cells. Virulence. 2020 12; 11(1):414-429.
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CD73 complexes with emmprin to regulate MMP-2 production from co-cultured sarcoma cells and fibroblasts. BMC Cancer. 2019 Sep 12; 19(1):912.
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Unfolding Role of a Danger Molecule Adenosine Signaling in Modulation of Microbial Infection and Host Cell Response. Int J Mol Sci. 2018 Jan 09; 19(1).
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Reducing CD73 expression by IL1?-Programmed Th17 cells improves immunotherapeutic control of tumors. Cancer Res. 2014 Nov 01; 74(21):6048-59.
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Cytosolic 5'-nucleotidase III (NT5C3): gene sequence variation and functional genomics. Pharmacogenet Genomics. 2009 Aug; 19(8):567-76.
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Adenosine nucleotides in bile. Am J Physiol. 1996 Feb; 270(2 Pt 1):G246-52.
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Thioridazine induces lipid peroxidation in myelin of rat brain. Neuropharmacology. 1993 Feb; 32(2):157-67.
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Calcium-activated neutral proteinase (calpain) activity in C6 cell line: compartmentation of mu and m calpain. J Neurosci Res. 1992 Apr; 31(4):708-14.
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Adrenal autoantibodies bind to adrenal subcellular fractions enriched in cytochrome-c reductase and 5'-nucleotidase. J Clin Endocrinol Metab. 1990 Jan; 70(1):95-9.