Systemic Inflammatory Response Syndrome
"Systemic Inflammatory Response Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever >38 degrees C or HYPOTHERMIA <36 degrees C; (2) TACHYCARDIA >90 beat/minute; (3) tachypnea >24 breaths/minute; (4) LEUKOCYTOSIS >12,000 cells/cubic mm or 10% immature forms. While usually related to infection, SIRS can also be associated with noninfectious insults such as TRAUMA; BURNS; or PANCREATITIS. If infection is involved, a patient with SIRS is said to have SEPSIS.
Descriptor ID |
D018746
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MeSH Number(s) |
C23.550.470.790 C23.550.835.900
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Systemic Inflammatory Response Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Systemic Inflammatory Response Syndrome".
- Systemic Inflammatory Response Syndrome
- Sepsis
This graph shows the total number of publications written about "Systemic Inflammatory Response Syndrome" by people in this website by year, and whether "Systemic Inflammatory Response Syndrome" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 0 | 1 |
1999 | 1 | 0 | 1 |
2001 | 1 | 0 | 1 |
2010 | 1 | 0 | 1 |
2012 | 3 | 1 | 4 |
2015 | 2 | 0 | 2 |
2016 | 1 | 1 | 2 |
2017 | 1 | 1 | 2 |
2019 | 2 | 0 | 2 |
2020 | 1 | 0 | 1 |
2021 | 5 | 2 | 7 |
2022 | 1 | 3 | 4 |
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Below are the most recent publications written about "Systemic Inflammatory Response Syndrome" by people in Profiles.
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Health Impairments in Children and Adolescents After Hospitalization for Acute COVID-19 or MIS-C. Pediatrics. 2022 09 01; 150(3).
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Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C. Nat Commun. 2022 05 27; 13(1):2979.
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Evaluation of mRNA-1273 Covid-19 Vaccine in Children 6 to 11 Years of Age. N Engl J Med. 2022 05 26; 386(21):2011-2023.
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Effectiveness of BNT162b2 (Pfizer-BioNTech) mRNA Vaccination Against Multisystem Inflammatory Syndrome in Children Among Persons Aged 12-18 Years - United States, July-December 2021. MMWR Morb Mortal Wkly Rep. 2022 Jan 14; 71(2):52-58.
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The relationship between pre-existing diabetes mellitus and the severity of acute pancreatitis: Report from a large international registry. Pancreatology. 2022 Jan; 22(1):85-91.
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Deaths in Children and Adolescents Associated With COVID-19 and MIS-C in the United States. Pediatrics. 2021 11; 148(5).
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Multisystem Inflammatory Syndrome in Children - Initial Therapy and Outcomes. N Engl J Med. 2021 07 01; 385(1):23-34.
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Neurologic Involvement in Children and Adolescents Hospitalized in the United States for COVID-19 or Multisystem Inflammatory Syndrome. JAMA Neurol. 2021 05 01; 78(5):536-547.
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Characteristics and Outcomes of US Children and Adolescents With Multisystem Inflammatory Syndrome in Children (MIS-C) Compared With Severe Acute COVID-19. JAMA. 2021 03 16; 325(11):1074-1087.
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Mortality in acute pancreatitis with persistent organ failure is determined by the number, type, and sequence of organ systems affected. United European Gastroenterol J. 2021 03; 9(2):139-149.