"Poloxamer" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)
| Descriptor ID |
D020442
|
| MeSH Number(s) |
D02.033.455.250.700.682 D05.750.741.667 D25.720.741.667 J01.637.051.720.741.667
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Poloxamer".
Below are MeSH descriptors whose meaning is more specific than "Poloxamer".
This graph shows the total number of publications written about "Poloxamer" by people in this website by year, and whether "Poloxamer" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2004 | 1 | 1 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Poloxamer" by people in Profiles.
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Effect of Poloxamer 188 vs Placebo on Painful Vaso-Occlusive Episodes in Children and Adults With Sickle Cell Disease: A Randomized Clinical Trial. JAMA. 2021 04 20; 325(15):1513-1523.
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Control of Vancomycin Activity through the Encapsulation and Controlled Release from a Propargyl Acrylate-Poloxamer Nanocomposite System. Langmuir. 2020 12 08; 36(48):14607-14613.
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Blinded Comparative Review of Lubricants Commonly Used for Split-Thickness Skin Graft Harvest. J Burn Care Res. 2019 04 26; 40(3):327-330.
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Role of Pluronic block copolymers in modulation of heat shock protein 70 expression. Int J Hyperthermia. 2011; 27(7):672-81.
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A double-blind, placebo-controlled trial of a topical treatment for chemotherapy-induced peripheral neuropathy: NCCTG trial N06CA. Support Care Cancer. 2011 Jun; 19(6):833-41.
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Pluronic F127-based systemic vaccine delivery systems. Vaccine. 2004 Jun 23; 22(19):2396-405.
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Safety of purified poloxamer 188 in sickle cell disease: phase I study of a non-ionic surfactant in the management of acute chest syndrome. Hemoglobin. 2004 May; 28(2):85-102.
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Evaluation of pluronic polyols as carriers for grafting materials: study in rat calvaria defects. J Periodontol. 2002 Feb; 73(2):191-7.
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ProJuvant (Pluronic F127/chitosan) enhances the immune response to intranasally administered tetanus toxoid. Vaccine. 2001 Dec 12; 20(5-6):711-23.