"Rats, Zucker" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Two populations of Zucker rats have been cited in research--the "fatty" or obese and the lean. The "fatty" rat (Rattus norvegicus) appeared as a spontaneous mutant. The obese condition appears to be due to a single recessive gene.
| Descriptor ID |
D011924
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| MeSH Number(s) |
B01.050.150.900.649.313.992.635.505.700.550.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Rats, Zucker".
Below are MeSH descriptors whose meaning is more specific than "Rats, Zucker".
This graph shows the total number of publications written about "Rats, Zucker" by people in this website by year, and whether "Rats, Zucker" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
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Below are the most recent publications written about "Rats, Zucker" by people in Profiles.
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Simvastatin inhibits LPS-induced alveolar bone loss during metabolic syndrome. J Dent Res. 2014 Mar; 93(3):294-9.
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Reduced endothelium-dependent relaxation to anandamide in mesenteric arteries from young obese Zucker rats. PLoS One. 2013; 8(5):e63449.
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Sphingolipid metabolism and analysis in metabolic disease. Adv Exp Med Biol. 2011; 721:1-17.
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Metformin selectively attenuates mitochondrial H2O2 emission without affecting respiratory capacity in skeletal muscle of obese rats. Free Radic Biol Med. 2010 Sep 15; 49(6):1082-7.
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Mammalian Tribbles homolog 3 impairs insulin action in skeletal muscle: role in glucose-induced insulin resistance. Am J Physiol Endocrinol Metab. 2010 Mar; 298(3):E565-76.
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Altered penile vascular reactivity and erection in the Zucker obese-diabetic rat. J Sex Med. 2007 Mar; 4(2):348-62; discussion 362-3.
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Obesity alters rat abdominal flap survival. Am Surg. 2006 Sep; 72(9):764-71; discussion 771-2.
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Memory impairment in obese Zucker rats: an investigation of cognitive function in an animal model of insulin resistance and obesity. Behav Neurosci. 2005 Oct; 119(5):1389-95.
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Identification of Rad's effector-binding domain, intracellular localization, and analysis of expression in Pima Indians. J Cell Biochem. 1997 Jun 15; 65(4):527-41.