"Pregnenolone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 21-carbon steroid, derived from CHOLESTEROL and found in steroid hormone-producing tissues. Pregnenolone is the precursor to GONADAL STEROID HORMONES and the adrenal CORTICOSTEROIDS.
| Descriptor ID |
D011284
|
| MeSH Number(s) |
D04.210.500.745.745.725 D06.472.040.585.745 D06.472.334.851.687.500
|
| Concept/Terms |
Pregnenolone- Pregnenolone
- 5-Pregnen-3-beta-ol-20-one
- 5 Pregnen 3 beta ol 20 one
|
Below are MeSH descriptors whose meaning is more general than "Pregnenolone".
Below are MeSH descriptors whose meaning is more specific than "Pregnenolone".
This graph shows the total number of publications written about "Pregnenolone" by people in this website by year, and whether "Pregnenolone" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pregnenolone" by people in Profiles.
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Initial genetic dissection of serum neuroactive steroids following chronic intermittent ethanol across BXD mouse strains. Alcohol. 2017 Feb; 58:107-125.
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Activation of steroid-sensitive TRPM3 channels potentiates glutamatergic transmission at cerebellar Purkinje neurons from developing rats. J Neurochem. 2011 Nov; 119(3):474-85.
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Pregnenolone sulfate increases glutamate release at neonatal climbing fiber-to-Purkinje cell synapses. Neuroscience. 2011 Feb 23; 175:24-36.