"Proton Pumps" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Integral membrane proteins that transport protons across a membrane. This transport can be linked to the hydrolysis of ADENOSINE TRIPHOSPHATE. What is referred to as proton pump inhibitors frequently is about POTASSIUM HYDROGEN ATPASE.
| Descriptor ID |
D017494
|
| MeSH Number(s) |
D12.776.157.530.450.250.875 D12.776.543.585.450.250.875
|
| Concept/Terms |
Proton Pumps- Proton Pumps
- Pumps, Proton
- H+ Pump
- Pump, H+
- Proton Pump
- Pump, Proton
- H(+) Pump
|
Below are MeSH descriptors whose meaning is more general than "Proton Pumps".
Below are MeSH descriptors whose meaning is more specific than "Proton Pumps".
This graph shows the total number of publications written about "Proton Pumps" by people in this website by year, and whether "Proton Pumps" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 2 | 2 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Proton Pumps" by people in Profiles.
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Helicobacter pylori virulence factors affecting gastric proton pump expression and acid secretion. Am J Physiol Gastrointest Liver Physiol. 2015 Aug 01; 309(3):G193-201.
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Optogenetic inhibition of cocaine seeking in rats. Addict Biol. 2013 Jan; 18(1):50-3.
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How Helicobacter pylori infection controls gastric acid secretion. J Gastroenterol. 2012 Jun; 47(6):609-18.
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Helicobacter pylori represses proton pump expression and inhibits acid secretion in human gastric mucosa. Gut. 2010 Jul; 59(7):874-81.
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Proton pump inhibitors in acute peptic ulcer bleeding. Gastroenterology. 2005 Aug; 129(2):756-7.
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Total acid suppression and its effect on Barrett's esophagus. Am J Manag Care. 2000 Oct; 6(16 Suppl):S895-8.
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Gastro-oesophageal reflux associated with nocturnal gastric acid breakthrough on proton pump inhibitors. Aliment Pharmacol Ther. 1998 Dec; 12(12):1231-4.
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Mutation of a surface residue, lysine-129, reverses the order of proton release and uptake in bacteriorhodopsin; guanidine hydrochloride restores it. Biophys J. 1997 Feb; 72(2 Pt 1):886-98.
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Probing of the retinal binding site of bacteriorhodopsin by affinity labeling. Biochemistry. 1994 Sep 27; 33(38):11624-30.