"Hybridomas" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cells artificially created by fusion of activated lymphocytes with neoplastic cells. The resulting hybrid cells are cloned and produce pure MONOCLONAL ANTIBODIES or T-cell products, identical to those produced by the immunologically competent parent cell.
| Descriptor ID |
D006825
|
| MeSH Number(s) |
A11.251.353.485 A11.251.600.485
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hybridomas".
Below are MeSH descriptors whose meaning is more specific than "Hybridomas".
This graph shows the total number of publications written about "Hybridomas" by people in this website by year, and whether "Hybridomas" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
| 2003 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hybridomas" by people in Profiles.
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CD4 Inhibits Helper T Cell Activation at Lower Affinity Threshold for Full-Length T Cell Receptors Than Single Chain Signaling Constructs. Front Immunol. 2020; 11:561889.
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Kidney-targeted inhibition of protein kinase C-a ameliorates nephrotoxic nephritis with restoration of mitochondrial dysfunction. Kidney Int. 2018 08; 94(2):280-291.
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Phosphorylation of radixin regulates cell polarity and Mrp-2 distribution in hepatocytes. Am J Physiol Cell Physiol. 2011 Mar; 300(3):C416-24.
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Value in development of a TAPIR-like mouse monoclonal antibody to Abeta. J Alzheimers Dis. 2008 Jun; 14(2):175-7.
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Monoclonal antibody to fibulin-1 generated by genetic immunization. J Cell Biochem. 2003 Jul 01; 89(4):647-52.
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Generation and characterization of species-specific anti-Bcl-X(L) monoclonal antibodies. Hybrid Hybridomics. 2003 Apr; 22(2):91-5.
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Highly cross-reactive T cell responses to myelin basic protein epitopes reveal a nonpredictable form of TCR degeneracy. J Immunol. 1999 Jun 01; 162(11):6451-7.
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Selection of specific phage from display libraries: monoclonal antibody against VCS M13 helper phage coat protein III (gIIIp). Hybridoma. 1999 Jun; 18(3):257-61.
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Differential tolerance is induced in T cells recognizing distinct epitopes of myelin basic protein. Immunity. 1998 May; 8(5):571-80.
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Structural features of nephritogenic lupus autoantibodies. Methods. 1997 Jan; 11(1):62-9.