"Fetal Hemoglobin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The major component of hemoglobin in the fetus. This HEMOGLOBIN has two alpha and two gamma polypeptide subunits in comparison to normal adult hemoglobin, which has two alpha and two beta polypeptide subunits. Fetal hemoglobin concentrations can be elevated (usually above 0.5%) in children and adults affected by LEUKEMIA and several types of ANEMIA.
| Descriptor ID |
D005319
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| MeSH Number(s) |
D12.776.124.400.303 D12.776.422.316.762.320
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Fetal Hemoglobin".
Below are MeSH descriptors whose meaning is more specific than "Fetal Hemoglobin".
This graph shows the total number of publications written about "Fetal Hemoglobin" by people in this website by year, and whether "Fetal Hemoglobin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 1 | 2 |
| 2000 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Fetal Hemoglobin" by people in Profiles.
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A double-blind, placebo-controlled phase II study of the efficacy and safety of 2,2-dimethylbutyrate (HQK-1001), an oral fetal globin inducer, in sickle cell disease. Am J Hematol. 2014 Jul; 89(7):709-13.
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A dose-escalation phase IIa study of 2,2-dimethylbutyrate (HQK-1001), an oral fetal globin inducer, in sickle cell disease. Am J Hematol. 2013 Nov; 88(11):E255-60.
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The effects of hydroxycarbamide and magnesium on haemoglobin SC disease: results of the multi-centre CHAMPS trial. Br J Haematol. 2011 Mar; 152(6):771-6.
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Spurious elevation of hemoglobin A1c by hereditary persistence of fetal hemoglobin. South Med J. 2000 Jan; 93(1):62-4.
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Myelodysplasia associated with Turner syndrome. J Pediatr Hematol Oncol. 1996 Aug; 18(3):299-301.
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Identification and quantification of hemoglobins A, F, S, and C by automated chromatography. Clin Chem. 1996 Jan; 42(1):57-63.
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Serum-free culture of enriched hematopoietic progenitors reflects physiologic levels of fetal hemoglobin biosynthesis. Blood. 1990 Apr 15; 75(8):1718-22.
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cDNA sequence of a new chicken embryonic rho-globin. Proc Natl Acad Sci U S A. 1981 Aug; 78(8):4782-5.