Connection

Yusuf Hannun to Type C Phospholipases

This is a "connection" page, showing publications Yusuf Hannun has written about Type C Phospholipases.
Connection Strength

3.363
  1. Yeast Sphingolipid Phospholipase Gene ISC1 Regulates the Spindle Checkpoint by a CDC55-Dependent Mechanism. Mol Cell Biol. 2020 05 28; 40(12).
    View in: PubMed
    Score: 0.673
  2. ISC1-dependent metabolic adaptation reveals an indispensable role for mitochondria in induction of nuclear genes during the diauxic shift in Saccharomyces cerevisiae. J Biol Chem. 2009 Apr 17; 284(16):10818-30.
    View in: PubMed
    Score: 0.307
  3. Hydroxyurea sensitivity reveals a role for ISC1 in the regulation of G2/M. J Biol Chem. 2009 Mar 27; 284(13):8241-6.
    View in: PubMed
    Score: 0.306
  4. Thematic review series: sphingolipids. ISC1 (inositol phosphosphingolipid-phospholipase C), the yeast homologue of neutral sphingomyelinases. J Lipid Res. 2008 May; 49(5):922-8.
    View in: PubMed
    Score: 0.288
  5. Isc1 regulates sphingolipid metabolism in yeast mitochondria. Biochim Biophys Acta. 2007 Nov; 1768(11):2849-61.
    View in: PubMed
    Score: 0.277
  6. Distinct roles for de novo versus hydrolytic pathways of sphingolipid biosynthesis in Saccharomyces cerevisiae. Biochem J. 2006 Feb 01; 393(Pt 3):733-40.
    View in: PubMed
    Score: 0.249
  7. Identification of ISC1 (YER019w) as inositol phosphosphingolipid phospholipase C in Saccharomyces cerevisiae. J Biol Chem. 2000 Dec 15; 275(50):39793-8.
    View in: PubMed
    Score: 0.175
  8. Function of the cloned putative neutral sphingomyelinase as lyso-platelet activating factor-phospholipase C. J Biol Chem. 1999 Dec 31; 274(53):38131-9.
    View in: PubMed
    Score: 0.164
  9. Acetic acid induces Sch9p-dependent translocation of Isc1p from the endoplasmic reticulum into mitochondria. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Jun; 1863(6):576-583.
    View in: PubMed
    Score: 0.144
  10. Identification of C18:1-phytoceramide as the candidate lipid mediator for hydroxyurea resistance in yeast. J Biol Chem. 2013 Jun 14; 288(24):17272-84.
    View in: PubMed
    Score: 0.103
  11. Modulation of mitochondrial outer membrane permeabilization and apoptosis by ceramide metabolism. PLoS One. 2012; 7(11):e48571.
    View in: PubMed
    Score: 0.100
  12. Cellular morphogenesis under stress is influenced by the sphingolipid pathway gene ISC1 and DNA integrity checkpoint genes in Saccharomyces cerevisiae. Genetics. 2011 Oct; 189(2):533-47.
    View in: PubMed
    Score: 0.091
  13. Role for Sit4p-dependent mitochondrial dysfunction in mediating the shortened chronological lifespan and oxidative stress sensitivity of Isc1p-deficient cells. Mol Microbiol. 2011 Jul; 81(2):515-27.
    View in: PubMed
    Score: 0.091
  14. The phosphatidylglycerol/cardiolipin biosynthetic pathway is required for the activation of inositol phosphosphingolipid phospholipase C, Isc1p, during growth of Saccharomyces cerevisiae. J Biol Chem. 2005 Feb 25; 280(8):7170-7.
    View in: PubMed
    Score: 0.058
  15. Activation and localization of inositol phosphosphingolipid phospholipase C, Isc1p, to the mitochondria during growth of Saccharomyces cerevisiae. J Biol Chem. 2004 Mar 19; 279(12):11537-45.
    View in: PubMed
    Score: 0.054
  16. Functional analysis of ISC1 by site-directed mutagenesis. Biochemistry. 2003 Jul 01; 42(25):7855-62.
    View in: PubMed
    Score: 0.052
  17. Biochemical properties of mammalian neutral sphingomyelinase 2 and its role in sphingolipid metabolism. J Biol Chem. 2003 Apr 18; 278(16):13775-83.
    View in: PubMed
    Score: 0.051
  18. Tight binding inhibition of protein phosphatase-1 by phosphatidic acid. Specificity of inhibition by the phospholipid. J Biol Chem. 2002 May 03; 277(18):15530-8.
    View in: PubMed
    Score: 0.047
  19. Proteolytic cleavage of phospholipase C-gamma1 during apoptosis in Molt-4 cells. FASEB J. 2000 Jun; 14(9):1083-92.
    View in: PubMed
    Score: 0.042
  20. Sphingomyelin synthase, a potential regulator of intracellular levels of ceramide and diacylglycerol during SV40 transformation. Does sphingomyelin synthase account for the putative phosphatidylcholine-specific phospholipase C? J Biol Chem. 1998 Jun 05; 273(23):14550-9.
    View in: PubMed
    Score: 0.037
  21. Sphingolipids and mitochondrial function in budding yeast. Biochim Biophys Acta. 2014 Oct; 1840(10):3131-7.
    View in: PubMed
    Score: 0.028
  22. The protein kinase Sch9 is a key regulator of sphingolipid metabolism in Saccharomyces cerevisiae. Mol Biol Cell. 2014 Jan; 25(1):196-211.
    View in: PubMed
    Score: 0.027
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.