"Type C Phospholipases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of phospholipases that hydrolyze the phosphoester bond found in the third position of GLYCEROPHOSPHOLIPIDS. Although the singular term phospholipase C specifically refers to an enzyme that catalyzes the hydrolysis of PHOSPHATIDYLCHOLINE (EC 3.1.4.3), it is commonly used in the literature to refer to broad variety of enzymes that specifically catalyze the hydrolysis of PHOSPHATIDYLINOSITOLS.
| Descriptor ID |
D010738
|
| MeSH Number(s) |
D08.811.277.352.640.700.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Type C Phospholipases".
Below are MeSH descriptors whose meaning is more specific than "Type C Phospholipases".
This graph shows the total number of publications written about "Type C Phospholipases" by people in this website by year, and whether "Type C Phospholipases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 4 | 4 |
| 1999 | 1 | 3 | 4 |
| 2000 | 2 | 2 | 4 |
| 2001 | 1 | 2 | 3 |
| 2002 | 1 | 3 | 4 |
| 2003 | 0 | 4 | 4 |
| 2004 | 1 | 3 | 4 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 1 | 2 | 3 |
| 2008 | 1 | 0 | 1 |
| 2009 | 2 | 0 | 2 |
| 2011 | 3 | 0 | 3 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Type C Phospholipases" by people in Profiles.
-
Yeast Sphingolipid Phospholipase Gene ISC1 Regulates the Spindle Checkpoint by a CDC55-Dependent Mechanism. Mol Cell Biol. 2020 05 28; 40(12).
-
Acetic acid induces Sch9p-dependent translocation of Isc1p from the endoplasmic reticulum into mitochondria. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Jun; 1863(6):576-583.
-
Sphingolipids and mitochondrial function in budding yeast. Biochim Biophys Acta. 2014 Oct; 1840(10):3131-7.
-
The protein kinase Sch9 is a key regulator of sphingolipid metabolism in Saccharomyces cerevisiae. Mol Biol Cell. 2014 Jan; 25(1):196-211.
-
Identification of C18:1-phytoceramide as the candidate lipid mediator for hydroxyurea resistance in yeast. J Biol Chem. 2013 Jun 14; 288(24):17272-84.
-
Modulation of mitochondrial outer membrane permeabilization and apoptosis by ceramide metabolism. PLoS One. 2012; 7(11):e48571.
-
Phospholipase C and protein kinase C-? 2 mediate insulin-like growth factor II-dependent sphingosine kinase 1 activation. Mol Endocrinol. 2011 Dec; 25(12):2144-56.
-
Cellular morphogenesis under stress is influenced by the sphingolipid pathway gene ISC1 and DNA integrity checkpoint genes in Saccharomyces cerevisiae. Genetics. 2011 Oct; 189(2):533-47.
-
Role for Sit4p-dependent mitochondrial dysfunction in mediating the shortened chronological lifespan and oxidative stress sensitivity of Isc1p-deficient cells. Mol Microbiol. 2011 Jul; 81(2):515-27.
-
Characterization of inositol phospho-sphingolipid-phospholipase C 1 (Isc1) in Cryptococcus neoformans reveals unique biochemical features. FEBS Lett. 2011 Feb 18; 585(4):635-40.