Connection

Yusuf Hannun to Saccharomyces cerevisiae

This is a "connection" page, showing publications Yusuf Hannun has written about Saccharomyces cerevisiae.
Connection Strength

8.522
  1. Yeast Sphingolipid Phospholipase Gene ISC1 Regulates the Spindle Checkpoint by a CDC55-Dependent Mechanism. Mol Cell Biol. 2020 05 28; 40(12).
    View in: PubMed
    Score: 0.616
  2. Tsc3 regulates SPT amino acid choice in Saccharomyces cerevisiae by promoting alanine in the sphingolipid pathway. J Lipid Res. 2018 11; 59(11):2126-2139.
    View in: PubMed
    Score: 0.545
  3. Quantification of 3-ketodihydrosphingosine using HPLC-ESI-MS/MS to study SPT activity in yeast Saccharomyces cerevisiae. J Lipid Res. 2018 01; 59(1):162-170.
    View in: PubMed
    Score: 0.515
  4. The yeast sphingolipid signaling landscape. Chem Phys Lipids. 2014 Jan; 177:26-40.
    View in: PubMed
    Score: 0.391
  5. Identification of C18:1-phytoceramide as the candidate lipid mediator for hydroxyurea resistance in yeast. J Biol Chem. 2013 Jun 14; 288(24):17272-84.
    View in: PubMed
    Score: 0.377
  6. Sphingoid bases and the serine catabolic enzyme CHA1 define a novel feedforward/feedback mechanism in the response to serine availability. J Biol Chem. 2012 Mar 16; 287(12):9280-9.
    View in: PubMed
    Score: 0.345
  7. Sphingolipids mediate formation of mRNA processing bodies during the heat-stress response of Saccharomyces cerevisiae. Biochem J. 2010 Oct 01; 431(1):31-8.
    View in: PubMed
    Score: 0.315
  8. ISC1-dependent metabolic adaptation reveals an indispensable role for mitochondria in induction of nuclear genes during the diauxic shift in Saccharomyces cerevisiae. J Biol Chem. 2009 Apr 17; 284(16):10818-30.
    View in: PubMed
    Score: 0.281
  9. Hydroxyurea sensitivity reveals a role for ISC1 in the regulation of G2/M. J Biol Chem. 2009 Mar 27; 284(13):8241-6.
    View in: PubMed
    Score: 0.280
  10. Coordination of the dynamics of yeast sphingolipid metabolism during the diauxic shift. Theor Biol Med Model. 2007 Oct 31; 4:42.
    View in: PubMed
    Score: 0.257
  11. Isc1 regulates sphingolipid metabolism in yeast mitochondria. Biochim Biophys Acta. 2007 Nov; 1768(11):2849-61.
    View in: PubMed
    Score: 0.254
  12. Selective substrate supply in the regulation of yeast de novo sphingolipid synthesis. J Biol Chem. 2007 Apr 20; 282(16):12330-40.
    View in: PubMed
    Score: 0.246
  13. Distinct roles for de novo versus hydrolytic pathways of sphingolipid biosynthesis in Saccharomyces cerevisiae. Biochem J. 2006 Feb 01; 393(Pt 3):733-40.
    View in: PubMed
    Score: 0.228
  14. Using genomic and lipidomic strategies to investigate sphingolipid function in the yeast heat-stress response. Biochem Soc Trans. 2005 Nov; 33(Pt 5):1166-9.
    View in: PubMed
    Score: 0.224
  15. Simulation and validation of modelled sphingolipid metabolism in Saccharomyces cerevisiae. Nature. 2005 Jan 27; 433(7024):425-30.
    View in: PubMed
    Score: 0.213
  16. The phosphatidylglycerol/cardiolipin biosynthetic pathway is required for the activation of inositol phosphosphingolipid phospholipase C, Isc1p, during growth of Saccharomyces cerevisiae. J Biol Chem. 2005 Feb 25; 280(8):7170-7.
    View in: PubMed
    Score: 0.211
  17. Activation and localization of inositol phosphosphingolipid phospholipase C, Isc1p, to the mitochondria during growth of Saccharomyces cerevisiae. J Biol Chem. 2004 Mar 19; 279(12):11537-45.
    View in: PubMed
    Score: 0.197
  18. Identification of ISC1 (YER019w) as inositol phosphosphingolipid phospholipase C in Saccharomyces cerevisiae. J Biol Chem. 2000 Dec 15; 275(50):39793-8.
    View in: PubMed
    Score: 0.160
  19. Role for de novo sphingoid base biosynthesis in the heat-induced transient cell cycle arrest of Saccharomyces cerevisiae. J Biol Chem. 2001 Mar 16; 276(11):8574-81.
    View in: PubMed
    Score: 0.158
  20. The juxtamembrane linker in neutral sphingomyelinase-2 functions as an intramolecular allosteric switch that activates the enzyme. J Biol Chem. 2019 05 03; 294(18):7488-7502.
    View in: PubMed
    Score: 0.142
  21. Acetic acid induces Sch9p-dependent translocation of Isc1p from the endoplasmic reticulum into mitochondria. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Jun; 1863(6):576-583.
    View in: PubMed
    Score: 0.132
  22. Involvement of yeast sphingolipids in the heat stress response of Saccharomyces cerevisiae. J Biol Chem. 1997 Dec 19; 272(51):32566-72.
    View in: PubMed
    Score: 0.130
  23. The BST1 gene of Saccharomyces cerevisiae is the sphingosine-1-phosphate lyase. J Biol Chem. 1997 Oct 17; 272(42):26087-90.
    View in: PubMed
    Score: 0.128
  24. Structure of human nSMase2 reveals an interdomain allosteric activation mechanism for ceramide generation. Proc Natl Acad Sci U S A. 2017 07 11; 114(28):E5549-E5558.
    View in: PubMed
    Score: 0.126
  25. Aging-related elevation of sphingoid bases shortens yeast chronological life span by compromising mitochondrial function. Oncotarget. 2016 Apr 19; 7(16):21124-44.
    View in: PubMed
    Score: 0.116
  26. Analysis of the Involvement of Different Ceramide Variants in the Response to Hydroxyurea Stress in Baker's Yeast. PLoS One. 2016; 11(1):e0146839.
    View in: PubMed
    Score: 0.114
  27. Dynamics of the Heat Stress Response of Ceramides with Different Fatty-Acyl Chain Lengths in Baker's Yeast. PLoS Comput Biol. 2015 Aug; 11(8):e1004373.
    View in: PubMed
    Score: 0.110
  28. Sphingolipids and mitochondrial function in budding yeast. Biochim Biophys Acta. 2014 Oct; 1840(10):3131-7.
    View in: PubMed
    Score: 0.102
  29. The plant decapeptide OSIP108 prevents copper-induced apoptosis in yeast and human cells. Biochim Biophys Acta. 2014 Jun; 1843(6):1207-1215.
    View in: PubMed
    Score: 0.100
  30. Sphingolipid signalling mediates mitochondrial dysfunctions and reduced chronological lifespan in the yeast model of Niemann-Pick type C1. Mol Microbiol. 2014 Feb; 91(3):438-51.
    View in: PubMed
    Score: 0.098
  31. The protein kinase Sch9 is a key regulator of sphingolipid metabolism in Saccharomyces cerevisiae. Mol Biol Cell. 2014 Jan; 25(1):196-211.
    View in: PubMed
    Score: 0.098
  32. Distinct signaling roles of ceramide species in yeast revealed through systematic perturbation and systems biology analyses. Sci Signal. 2013 Oct 29; 6(299):rs14.
    View in: PubMed
    Score: 0.098
  33. Coordination of rapid sphingolipid responses to heat stress in yeast. PLoS Comput Biol. 2013; 9(5):e1003078.
    View in: PubMed
    Score: 0.095
  34. Ceramide-mediated growth inhibition and CAPP are conserved in Saccharomyces cerevisiae. J Biol Chem. 1993 May 05; 268(13):9255-61.
    View in: PubMed
    Score: 0.094
  35. Modulation of mitochondrial outer membrane permeabilization and apoptosis by ceramide metabolism. PLoS One. 2012; 7(11):e48571.
    View in: PubMed
    Score: 0.092
  36. Mathematical modeling and validation of the ergosterol pathway in Saccharomyces cerevisiae. PLoS One. 2011; 6(12):e28344.
    View in: PubMed
    Score: 0.086
  37. Cellular morphogenesis under stress is influenced by the sphingolipid pathway gene ISC1 and DNA integrity checkpoint genes in Saccharomyces cerevisiae. Genetics. 2011 Oct; 189(2):533-47.
    View in: PubMed
    Score: 0.084
  38. Role for Sit4p-dependent mitochondrial dysfunction in mediating the shortened chronological lifespan and oxidative stress sensitivity of Isc1p-deficient cells. Mol Microbiol. 2011 Jul; 81(2):515-27.
    View in: PubMed
    Score: 0.083
  39. Identification of novel anionic phospholipid binding domains in neutral sphingomyelinase 2 with selective binding preference. J Biol Chem. 2011 Jun 24; 286(25):22362-71.
    View in: PubMed
    Score: 0.082
  40. Revealing a signaling role of phytosphingosine-1-phosphate in yeast. Mol Syst Biol. 2010; 6:349.
    View in: PubMed
    Score: 0.075
  41. Skn1 and Ipt1 negatively regulate autophagy in Saccharomyces cerevisiae. FEMS Microbiol Lett. 2010 Feb; 303(2):163-8.
    View in: PubMed
    Score: 0.074
  42. Identification of a novel amidase motif in neutral ceramidase. Biochem J. 2006 Feb 01; 393(Pt 3):687-95.
    View in: PubMed
    Score: 0.057
  43. Integration of kinetic information on yeast sphingolipid metabolism in dynamical pathway models. J Theor Biol. 2004 Feb 07; 226(3):265-91.
    View in: PubMed
    Score: 0.050
  44. Ceramide, stress, and a "LAG" in aging. Sci Aging Knowledge Environ. 2003 Oct 01; 2003(39):PE27.
    View in: PubMed
    Score: 0.049
  45. Roles for sphingolipid biosynthesis in mediation of specific programs of the heat stress response determined through gene expression profiling. J Biol Chem. 2003 Aug 08; 278(32):30328-38.
    View in: PubMed
    Score: 0.047
  46. Biochemical properties of mammalian neutral sphingomyelinase 2 and its role in sphingolipid metabolism. J Biol Chem. 2003 Apr 18; 278(16):13775-83.
    View in: PubMed
    Score: 0.046
  47. Phytosphingosine as a specific inhibitor of growth and nutrient import in Saccharomyces cerevisiae. J Biol Chem. 2001 Sep 21; 276(38):35614-21.
    View in: PubMed
    Score: 0.042
  48. Enzymes of sphingolipid metabolism: from modular to integrative signaling. Biochemistry. 2001 Apr 24; 40(16):4893-903.
    View in: PubMed
    Score: 0.041
  49. Sphingolipids signal heat stress-induced ubiquitin-dependent proteolysis. J Biol Chem. 2000 Jun 09; 275(23):17229-32.
    View in: PubMed
    Score: 0.039
  50. Identification and characterization of Saccharomyces cerevisiae dihydrosphingosine-1-phosphate phosphatase. J Biol Chem. 1997 Nov 07; 272(45):28690-4.
    View in: PubMed
    Score: 0.032
  51. The ceramide activated protein phosphatase Sit4 impairs sphingolipid dynamics, mitochondrial function and lifespan in a yeast model of Niemann-Pick type C1. Biochim Biophys Acta Mol Basis Dis. 2018 Jan; 1864(1):79-88.
    View in: PubMed
    Score: 0.032
  52. Molecular cloning and characterization of OsCDase, a ceramidase enzyme from rice. Plant J. 2008 Sep; 55(6):1000-9.
    View in: PubMed
    Score: 0.017
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.