Yusuf Hannun to Up-Regulation
This is a "connection" page, showing publications Yusuf Hannun has written about Up-Regulation.
Connection Strength
2.012
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P53-dependent upregulation of neutral sphingomyelinase-2: role in doxorubicin-induced growth arrest. Cell Death Dis. 2015 Oct 29; 6:e1947.
Score: 0.414
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Activation of p38 Mitogen-Activated Protein Kinase in Gaucher's Disease. PLoS One. 2015; 10(8):e0136633.
Score: 0.409
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Roles for sphingolipid biosynthesis in mediation of specific programs of the heat stress response determined through gene expression profiling. J Biol Chem. 2003 Aug 08; 278(32):30328-38.
Score: 0.175
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Upregulation of sphingosine kinase 1 in response to doxorubicin generates an angiogenic response via stabilization of Snail. FASEB J. 2023 03; 37(3):e22787.
Score: 0.172
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Loss of acid ceramidase in myeloid cells suppresses intestinal neutrophil recruitment. FASEB J. 2018 05; 32(5):2339-2353.
Score: 0.120
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ATRA transcriptionally induces nSMase2 through CBP/p300-mediated histone acetylation. J Lipid Res. 2016 05; 57(5):868-81.
Score: 0.107
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Evaluation of the role of secretory sphingomyelinase and bioactive sphingolipids as biomarkers in hemophagocytic lymphohistiocytosis. Am J Hematol. 2013 Nov; 88(11):E265-72.
Score: 0.089
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Neutral sphingomyelinase 2 (nSMase2) is the primary neutral sphingomyelinase isoform activated by tumour necrosis factor-a in MCF-7 cells. Biochem J. 2011 Apr 15; 435(2):381-90.
Score: 0.076
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Acid ceramidase upregulation in prostate cancer cells confers resistance to radiation: AC inhibition, a potential radiosensitizer. Mol Ther. 2009 Mar; 17(3):430-8.
Score: 0.064
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Sphingosine kinase 1 is up-regulated in colon carcinogenesis. FASEB J. 2006 Feb; 20(2):386-8.
Score: 0.052
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Alkaline ceramidase 2 and its bioactive product sphingosine are novel regulators of the DNA damage response. Oncotarget. 2016 Apr 05; 7(14):18440-57.
Score: 0.027
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Alkaline ceramidase 3 deficiency aggravates colitis and colitis-associated tumorigenesis in mice by hyperactivating the innate immune system. Cell Death Dis. 2016 Mar 03; 7:e2124.
Score: 0.027
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Loss of neutral ceramidase protects cells from nutrient- and energy -deprivation-induced cell death. Biochem J. 2016 Mar 15; 473(6):743-55.
Score: 0.026
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A novel role of sphingosine kinase-1 in the invasion and angiogenesis of VHL mutant clear cell renal cell carcinoma. FASEB J. 2015 Jul; 29(7):2803-13.
Score: 0.025
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GPR40/FFA1 and neutral sphingomyelinase are involved in palmitate-boosted inflammatory response of microvascular endothelial cells to LPS. Atherosclerosis. 2015 May; 240(1):163-73.
Score: 0.025
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Bone-specific insulin resistance disrupts whole-body glucose homeostasis via decreased osteocalcin activation. J Clin Invest. 2014 Apr; 124(4):1-13.
Score: 0.023
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Safety study of adeno-associated virus serotype 2-mediated human acid sphingomyelinase expression in the nonhuman primate brain. Hum Gene Ther. 2012 Aug; 23(8):891-902.
Score: 0.021
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Acid ceramidase-mediated production of sphingosine 1-phosphate promotes prostate cancer invasion through upregulation of cathepsin B. Int J Cancer. 2012 Nov 01; 131(9):2034-43.
Score: 0.020
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Selective knockdown of ceramide synthases reveals complex interregulation of sphingolipid metabolism. J Lipid Res. 2011 Jan; 52(1):68-77.
Score: 0.018
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Acid ceramidase upregulation in prostate cancer: role in tumor development and implications for therapy. Expert Opin Ther Targets. 2009 Dec; 13(12):1449-58.
Score: 0.017
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Potentiation of cannabinoid-induced cytotoxicity in mantle cell lymphoma through modulation of ceramide metabolism. Mol Cancer Res. 2009 Jul; 7(7):1086-98.
Score: 0.017
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Ceramide generated by sphingomyelin hydrolysis and the salvage pathway is involved in hypoxia/reoxygenation-induced Bax redistribution to mitochondria in NT-2 cells. J Biol Chem. 2008 Sep 26; 283(39):26509-17.
Score: 0.016
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De novo N-palmitoylsphingosine synthesis is the major biochemical mechanism of ceramide accumulation following p53 up-regulation. Prostaglandins Other Lipid Mediat. 2008 Jun; 86(1-4):41-8.
Score: 0.015
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Involvement of sphingolipids in apoptin-induced cell killing. Mol Ther. 2006 Nov; 14(5):627-36.
Score: 0.014
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Dihydrosphingosine 1-phosphate stimulates MMP1 gene expression via activation of ERK1/2-Ets1 pathway in human fibroblasts. FASEB J. 2006 Jan; 20(1):184-6.
Score: 0.013
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Down-regulation of sphingosine kinase-1 by DNA damage: dependence on proteases and p53. J Biol Chem. 2004 May 07; 279(19):20546-54.
Score: 0.012
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Sphingomyelin synthase as a potential target for D609-induced apoptosis in U937 human monocytic leukemia cells. Exp Cell Res. 2004 Jan 15; 292(2):385-92.
Score: 0.011
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Upregulation of Bcl-2 and elevation of ceramide in Batten disease. Neuropediatrics. 1997 Feb; 28(1):37-41.
Score: 0.007