Connection

Yusuf Hannun to Down-Regulation

This is a "connection" page, showing publications Yusuf Hannun has written about Down-Regulation.
Connection Strength

0.809
  1. Downregulation of neutral ceramidase by gemcitabine: Implications for cell cycle regulation. Biochim Biophys Acta. 2009 Aug; 1791(8):730-9.
    View in: PubMed
    Score: 0.279
  2. Roles for sphingolipid biosynthesis in mediation of specific programs of the heat stress response determined through gene expression profiling. J Biol Chem. 2003 Aug 08; 278(32):30328-38.
    View in: PubMed
    Score: 0.185
  3. Role of ceramide-activated protein phosphatase in ceramide-mediated signal transduction. J Biol Chem. 1994 Jul 29; 269(30):19605-9.
    View in: PubMed
    Score: 0.101
  4. Down-regulation of sphingosine kinase-1 by DNA damage: dependence on proteases and p53. J Biol Chem. 2004 May 07; 279(19):20546-54.
    View in: PubMed
    Score: 0.049
  5. Sphingosine kinase 1 downregulation is required for adaptation to serine deprivation. FASEB J. 2021 02; 35(2):e21284.
    View in: PubMed
    Score: 0.040
  6. A novel role of sphingosine kinase-1 in the invasion and angiogenesis of VHL mutant clear cell renal cell carcinoma. FASEB J. 2015 Jul; 29(7):2803-13.
    View in: PubMed
    Score: 0.026
  7. Off-target function of the Sonic hedgehog inhibitor cyclopamine in mediating apoptosis via nitric oxide-dependent neutral sphingomyelinase 2/ceramide induction. Mol Cancer Ther. 2012 May; 11(5):1092-102.
    View in: PubMed
    Score: 0.021
  8. Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling. FASEB J. 2009 Mar; 23(3):751-63.
    View in: PubMed
    Score: 0.017
  9. Role of acid ceramidase in resistance to FasL: therapeutic approaches based on acid ceramidase inhibitors and FasL gene therapy. Mol Ther. 2007 Jul; 15(7):1259-63.
    View in: PubMed
    Score: 0.015
  10. Involvement of sphingolipids in apoptin-induced cell killing. Mol Ther. 2006 Nov; 14(5):627-36.
    View in: PubMed
    Score: 0.015
  11. Resistance to TRAIL is associated with defects in ceramide signaling that can be overcome by exogenous C6-ceramide without requiring down-regulation of cellular FLICE inhibitory protein. Mol Cancer Ther. 2005 Sep; 4(9):1320-7.
    View in: PubMed
    Score: 0.014
  12. Tumor necrosis factor induces the loss of sphingosine kinase-1 by a cathepsin B-dependent mechanism. J Biol Chem. 2005 Apr 29; 280(17):17196-202.
    View in: PubMed
    Score: 0.013
  13. Sphingomyelin synthase as a potential target for D609-induced apoptosis in U937 human monocytic leukemia cells. Exp Cell Res. 2004 Jan 15; 292(2):385-92.
    View in: PubMed
    Score: 0.012
  14. Ceramide kinase mediates cytokine- and calcium ionophore-induced arachidonic acid release. J Biol Chem. 2003 Oct 03; 278(40):38206-13.
    View in: PubMed
    Score: 0.012
  15. Roles for inositol-phosphoryl ceramide synthase 1 (IPC1) in pathogenesis of C. neoformans. Genes Dev. 2001 Jan 15; 15(2):201-12.
    View in: PubMed
    Score: 0.010
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.