Suhua Sha

Title
InstitutionMedical University of South Carolina
DepartmentPathology and Laboratory Medicine
AddressP.O. Box MSC 908
RS403E
39 Sabin Street
Phone843-792-8324
Fax843-792-4157
vCardDownload vCard

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Wu F, Sambamurti K, Sha S. Current Advances in Adeno-Associated Virus-Mediated Gene Therapy to Prevent Acquired Hearing Loss. J Assoc Res Otolaryngol. 2022 10; 23(5):569-578. PMID: 36002664; PMCID: PMC9613825.
      Citations:    Fields:    Translation:AnimalsCells
    2. He Z, Kong W, Zou S, Huang H, Sha S, He Z, Kong W, Zou S, Huang H, Sha S. Editorial: Hearing Loss: From Pathogenesis to Treatment. Front Cell Neurosci. 2022; 16:907483. PMID: 35755783; PMCID: PMC9231520.
      Citations:    
    3. Wu F, Hill K, Fang Q, He Z, Zheng H, Wang X, Xiong H, Sha SH, Wu F, Hill K, Fang Q, He Z, Zheng H, Wang X, Xiong H, Sha SH. Traumatic-noise-induced hair cell death and hearing loss is mediated by activation of CaMKK?. Cell Mol Life Sci. 2022 Apr 19; 79(5):249. PMID: 35438341.
      Citations: 1     Fields:    Translation:HumansCells
    4. He ZH, Pan S, Zheng HW, Fang QJ, Hill K, Sha SH, He ZH, Pan S, Zheng HW, Fang QJ, Hill K, Sha SH. Treatment With Calcineurin Inhibitor FK506 Attenuates Noise-Induced Hearing Loss. Front Cell Dev Biol. 2021; 9:648461. PMID: 33777956; PMCID: PMC7994600.
      Citations:    
    5. Sonousi A, Quirke JCK, Waduge P, Janusic T, Gysin M, Haldimann K, Xu S, Hobbie SN, Sha SH, Schacht J, Chow CS, Vasella A, B?ttger EC, Crich D. An Advanced Apralog with Increased in vitro and in vivo Activity toward Gram-negative Pathogens and Reduced ex vivo Cochleotoxicity. ChemMedChem. 2021 01 19; 16(2):335-339. PMID: 33007139; PMCID: PMC7855274.
      Citations:    
    6. Quirke JCK, Rajasekaran P, Sarpe VA, Sonousi A, Osinnii I, Gysin M, Haldimann K, Fang QJ, Shcherbakov D, Hobbie SN, Sha SH, Schacht J, Vasella A, B?ttger EC, Crich D. Apralogs: Apramycin 5-O-Glycosides and Ethers with Improved Antibacterial Activity and Ribosomal Selectivity and Reduced Susceptibility to the Aminoacyltranserferase (3)-IV Resistance Determinant. J Am Chem Soc. 2020 01 08; 142(1):530-544. PMID: 31790244; PMCID: PMC6949408.
      Citations:    
    7. Wu F, Xiong H, Sha S, Wu F, Xiong H, Sha S. Noise-induced loss of sensory hair cells is mediated by ROS/AMPKa pathway. Redox Biol. 2020 01; 29:101406. PMID: 31926629; PMCID: PMC6933152.
      Citations:    
    8. Fang QJ, Wu F, Chai R, Sha SH, Fang QJ, Wu F, Chai R, Sha SH. Cochlear Surface Preparation in the Adult Mouse. J Vis Exp. 2019 11 06; (153). PMID: 31762458; PMCID: PMC7217453.
      Citations:    
    9. Fang Q, Zhang Y, Da P, Shao B, Pan H, He Z, Cheng C, Li D, Guo J, Wu X, Guan M, Liao M, Zhang Y, Sha S, Zhou Z, Wang J, Wang T, Su K, Chai R, Chen F, Fang Q, Zhang Y, Da P, Shao B, Pan H, He Z, Cheng C, Li D, Guo J, Wu X, Guan M, Liao M, Zhang Y, Sha S, Zhou Z, Wang J, Wang T, Su K, Chai R, Chen F. Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function. Sci Rep. 2019 03 04; 9(1):3357. PMID: 30833597; PMCID: PMC6399249.
      Citations:    
    10. Xiong H, Long H, Pan S, Lai R, Wang X, Zhu Y, Hill K, Fang Q, Zheng Y, Sha SH, Xiong H, Long H, Pan S, Lai R, Wang X, Zhu Y, Hill K, Fang Q, Zheng Y, Sha SH. Inhibition of Histone Methyltransferase G9a Attenuates Noise-Induced Cochlear Synaptopathy and Hearing Loss. J Assoc Res Otolaryngol. 2019 06; 20(3):217-232. PMID: 30710318; PMCID: PMC6513956.
      Citations:    
    11. Wang X, Zhu Y, Long H, Pan S, Xiong H, Fang Q, Hill K, Lai R, Yuan H, Sha SH, Wang X, Zhu Y, Long H, Pan S, Xiong H, Fang Q, Hill K, Lai R, Yuan H, Sha SH. Mitochondrial Calcium Transporters Mediate Sensitivity to Noise-Induced Losses of Hair Cells and Cochlear Synapses. Front Mol Neurosci. 2018; 11:469. PMID: 30670946; PMCID: PMC6331433.
      Citations:    
    12. Yang CH, Liu Z, Dong D, Schacht J, Arya D, Sha SH. Histone Deacetylase Inhibitors Are Protective in Acute but Not in Chronic Models of Ototoxicity. Front Cell Neurosci. 2017; 11:315. PMID: 29114207; PMCID: PMC5660723.
      Citations:    
    13. He Z, Guo L, Shu Y, Fang Q, Zhou H, Liu Y, Liu D, Lu L, Zhang X, Ding X, Liu D, Tang M, Kong W, Sha S, Li H, Gao X, Chai R, He Z, Guo L, Shu Y, Fang Q, Zhou H, Liu Y, Liu D, Lu L, Zhang X, Ding X, Liu D, Tang M, Kong W, Sha S, Li H, Gao X, Chai R. Autophagy protects auditory hair cells against neomycin-induced damage. Autophagy. 2017; 13(11):1884-1904. PMID: 28968134; PMCID: PMC5788479.
      Citations:    
    14. Sha SH, Schacht J, Sha SH, Schacht J. Emerging therapeutic interventions against noise-induced hearing loss. Expert Opin Investig Drugs. 2017 Jan; 26(1):85-96. PMID: 27918210; PMCID: PMC5527323.
      Citations:    
    15. Hill K, Yuan H, Wang X, Sha SH, Hill K, Yuan H, Wang X, Sha SH. Noise-Induced Loss of Hair Cells and Cochlear Synaptopathy Are Mediated by the Activation of AMPK. J Neurosci. 2016 07 13; 36(28):7497-510. PMID: 27413159; PMCID: PMC4945669.
      Citations:    
    16. Chen J, Hill K, Sha SH, Chen J, Hill K, Sha SH. Inhibitors of Histone Deacetylases Attenuate Noise-Induced Hearing Loss. J Assoc Res Otolaryngol. 2016 08; 17(4):289-302. PMID: 27095478; PMCID: PMC4940287.
      Citations:    
    17. Haque K, Pandey AK, Zheng HW, Riazuddin S, Sha SH, Puligilla C, Haque K, Pandey AK, Zheng HW, Riazuddin S, Sha SH, Puligilla C. MEKK4 Signaling Regulates Sensory Cell Development and Function in the Mouse Inner Ear. J Neurosci. 2016 Jan 27; 36(4):1347-61. PMID: 26818521; PMCID: PMC4728730.
      Citations:    
    18. Yuan H, Wang X, Hill K, Chen J, Lemasters J, Yang SM, Sha SH, Yuan H, Wang X, Hill K, Chen J, Lemasters J, Yang SM, Sha SH. Autophagy attenuates noise-induced hearing loss by reducing oxidative stress. Antioxid Redox Signal. 2015 May 20; 22(15):1308-24. PMID: 25694169; PMCID: PMC4410759.
      Citations:    
    19. Chen J, Yuan H, Talaska AE, Hill K, Sha SH, Chen J, Yuan H, Talaska AE, Hill K, Sha SH. Increased Sensitivity to Noise-Induced Hearing Loss by Blockade of Endogenous PI3K/Akt Signaling. J Assoc Res Otolaryngol. 2015 Jun; 16(3):347-56. PMID: 25790950; PMCID: PMC4417093.
      Citations:    
    20. Han Y, Wang X, Chen J, Sha SH, Han Y, Wang X, Chen J, Sha SH. Noise-induced cochlear F-actin depolymerization is mediated via ROCK2/p-ERM signaling. J Neurochem. 2015 Jun; 133(5):617-28. PMID: 25683353; PMCID: PMC4406832.
      Citations:    
    21. Zheng HW, Chen J, Sha SH, Zheng HW, Chen J, Sha SH. Receptor-interacting protein kinases modulate noise-induced sensory hair cell death. Cell Death Dis. 2014 May 29; 5:e1262. PMID: 24874734; PMCID: PMC4047918.
      Citations:    
    22. Oishi N, Chen J, Zheng HW, Hill K, Schacht J, Sha SH, Oishi N, Chen J, Zheng HW, Hill K, Schacht J, Sha SH. Tumor necrosis factor-alpha-mutant mice exhibit high frequency hearing loss. J Assoc Res Otolaryngol. 2013 Dec; 14(6):801-11. PMID: 23996384; PMCID: PMC3825018.
      Citations:    
    23. Chen FQ, Zheng HW, Schacht J, Sha SH, Chen FQ, Zheng HW, Schacht J, Sha SH. Mitochondrial peroxiredoxin 3 regulates sensory cell survival in the cochlea. PLoS One. 2013; 8(4):e61999. PMID: 23626763; PMCID: PMC3633911.
      Citations:    
    24. Oishi N, Chen FQ, Zheng HW, Sha SH, Oishi N, Chen FQ, Zheng HW, Sha SH. Intra-tympanic delivery of short interfering RNA into the adult mouse cochlea. Hear Res. 2013 Feb; 296:36-41. PMID: 23183031; PMCID: PMC3557582.
      Citations:    
    25. Chen FQ, Zheng HW, Hill K, Sha SH, Chen FQ, Zheng HW, Hill K, Sha SH. Traumatic noise activates Rho-family GTPases through transient cellular energy depletion. J Neurosci. 2012 Sep 05; 32(36):12421-30. PMID: 22956833; PMCID: PMC3445016.
      Citations:    
    26. Matt T, Ng CL, Lang K, Sha SH, Akbergenov R, Shcherbakov D, Meyer M, Duscha S, Xie J, Dubbaka SR, Perez-Fernandez D, Vasella A, Ramakrishnan V, Schacht J, Böttger EC, Matt T, Ng CL, Lang K, Sha SH, Akbergenov R, Shcherbakov D, Meyer M, Duscha S, Xie J, Dubbaka SR, Perez-Fernandez D, Vasella A, Ramakrishnan V, Schacht J, B?ttger EC. Dissociation of antibacterial activity and aminoglycoside ototoxicity in the 4-monosubstituted 2-deoxystreptamine apramycin. Proc Natl Acad Sci U S A. 2012 Jul 03; 109(27):10984-9. PMID: 22699498; PMCID: PMC3390888.
      Citations:    
    27. Chen FQ, Hill K, Guan YJ, Schacht J, Sha SH, Chen FQ, Hill K, Guan YJ, Schacht J, Sha SH. Activation of apoptotic pathways in the absence of cell death in an inner-ear immortomouse cell line. Hear Res. 2012 Feb; 284(1-2):33-41. PMID: 22240458; PMCID: PMC3289757.
      Citations:    
    28. Sha SH, Kanicki A, Halsey K, Wearne KA, Schacht J, Sha SH, Kanicki A, Halsey K, Wearne KA, Schacht J. Antioxidant-enriched diet does not delay the progression of age-related hearing loss. Neurobiol Aging. 2012 May; 33(5):1010.e15-6. PMID: 22154190; PMCID: PMC3306450.
      Citations:    
    29. Beyer LA, Galano MM, Nair TS, Kommareddi PK, Sha SH, Raphael Y, Carey TE, Beyer LA, Galano MM, Nair TS, Kommareddi PK, Sha SH, Raphael Y, Carey TE. Age-related changes in expression of CTL2/SLC44A2 and its isoforms in the mouse inner ear. Hear Res. 2011 Dec; 282(1-2):63-8. PMID: 21986210; PMCID: PMC3230667.
      Citations:    
    30. Sha SH, Chen FQ, Schacht J, Sha SH, Chen FQ, Schacht J. PTEN attenuates PIP3/Akt signaling in the cochlea of the aging CBA/J mouse. Hear Res. 2010 Jun 01; 264(1-2):86-92. PMID: 19761823; PMCID: PMC2868099.
      Citations:    
    31. Sha SH, Chen FQ, Schacht J, Sha SH, Chen FQ, Schacht J. Activation of cell death pathways in the inner ear of the aging CBA/J mouse. Hear Res. 2009 Aug; 254(1-2):92-9. PMID: 19422898; PMCID: PMC2749985.
      Citations:    
    32. Chen FQ, Schacht J, Sha SH, Chen FQ, Schacht J, Sha SH. Aminoglycoside-induced histone deacetylation and hair cell death in the mouse cochlea. J Neurochem. 2009 Mar; 108(5):1226-36. PMID: 19141081; PMCID: PMC3341988.
      Citations:    
    33. Sha SH, Kanicki A, Dootz G, Talaska AE, Halsey K, Dolan D, Altschuler R, Schacht J, Sha SH, Kanicki A, Dootz G, Talaska AE, Halsey K, Dolan D, Altschuler R, Schacht J. Age-related auditory pathology in the CBA/J mouse. Hear Res. 2008 Sep; 243(1-2):87-94. PMID: 18573325; PMCID: PMC2577824.
      Citations:    
    34. Jiang H, Talaska AE, Schacht J, Sha SH, Jiang H, Talaska AE, Schacht J, Sha SH. Oxidative imbalance in the aging inner ear. Neurobiol Aging. 2007 Oct; 28(10):1605-12. PMID: 16920227; PMCID: PMC2453750.
      Citations:    
    35. Jiang H, Sha SH, Schacht J, Jiang H, Sha SH, Schacht J. Kanamycin alters cytoplasmic and nuclear phosphoinositide signaling in the organ of Corti in vivo. J Neurochem. 2006 Oct; 99(1):269-76. PMID: 16903869.
      Citations:    
    36. Chen Y, Huang WG, Zha DJ, Qiu JH, Wang JL, Sha SH, Schacht J, Chen Y, Huang WG, Zha DJ, Qiu JH, Wang JL, Sha SH, Schacht J. Aspirin attenuates gentamicin ototoxicity: from the laboratory to the clinic. Hear Res. 2007 Apr; 226(1-2):178-82. PMID: 16844331.
      Citations:    
    37. Jiang H, Sha SH, Schacht J, Jiang H, Sha SH, Schacht J. Rac/Rho pathway regulates actin depolymerization induced by aminoglycoside antibiotics. J Neurosci Res. 2006 Jun; 83(8):1544-51. PMID: 16521128; PMCID: PMC1525046.
      Citations:    
    38. Sha SH, Qiu JH, Schacht J, Sha SH, Qiu JH, Schacht J. Aspirin to prevent gentamicin-induced hearing loss. N Engl J Med. 2006 Apr 27; 354(17):1856-7. PMID: 16641409.
      Citations:    
    39. Jiang H, Sha SH, Schacht J, Jiang H, Sha SH, Schacht J. NF-kappaB pathway protects cochlear hair cells from aminoglycoside-induced ototoxicity. J Neurosci Res. 2005 Mar 01; 79(5):644-51. PMID: 15672440.
      Citations:    
    40. Endo T, Nakagawa T, Iguchi F, Kita T, Okano T, Sha SH, Schacht J, Shiga A, Kim TS, Ito J, Endo T, Nakagawa T, Iguchi F, Kita T, Okano T, Sha SH, Schacht J, Shiga A, Kim TS, Ito J. Elevation of superoxide dismutase increases acoustic trauma from noise exposure. Free Radic Biol Med. 2005 Feb 15; 38(4):492-8. PMID: 15649651.
      Citations:    
    41. Minami SB, Sha SH, Schacht J, Minami SB, Sha SH, Schacht J. Antioxidant protection in a new animal model of cisplatin-induced ototoxicity. Hear Res. 2004 Dec; 198(1-2):137-43. PMID: 15567610.
      Citations:    
    42. Kawamoto K, Sha SH, Minoda R, Izumikawa M, Kuriyama H, Schacht J, Raphael Y, Kawamoto K, Sha SH, Minoda R, Izumikawa M, Kuriyama H, Schacht J, Raphael Y. Antioxidant gene therapy can protect hearing and hair cells from ototoxicity. Mol Ther. 2004 Feb; 9(2):173-81. PMID: 14759801.
      Citations: 53     Fields:    Translation:AnimalsCells
    43. Wang AM, Sha SH, Lesniak W, Schacht J, Wang AM, Sha SH, Lesniak W, Schacht J. Tanshinone (Salviae miltiorrhizae extract) preparations attenuate aminoglycoside-induced free radical formation in vitro and ototoxicity in vivo. Antimicrob Agents Chemother. 2003 Jun; 47(6):1836-41. PMID: 12760856; PMCID: PMC155857.
      Citations: 32     Fields:    Translation:AnimalsCells
    44. Li G, Sha SH, Zotova E, Arezzo J, Van de Water T, Schacht J, Li G, Sha SH, Zotova E, Arezzo J, Van de Water T, Schacht J. Salicylate protects hearing and kidney function from cisplatin toxicity without compromising its oncolytic action. Lab Invest. 2002 May; 82(5):585-96. PMID: 12003999.
      Citations: 31     Fields:    Translation:AnimalsCells
    Sha's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (256)
    Explore
    _
    Co-Authors (3)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _