Truman R. Brown, PhD

TitleEndowed Chair, Stephen S. Schabel Endowed Chair in Radiology
InstitutionMedical University of South Carolina
DepartmentRadiology and Radiological Science
AddressP.O. Box MSC 323
205
Bioengineering Bldg - 68 President St.
Phone843-876-2462
Fax843-876-2469
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    Healthy Volunteer Studies, Mental Health

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Roberts DR, Zhu X, Tabesh A, Duffy EW, Ramsey DA, Brown TR, Roberts DR, Zhu X, Tabesh A, Duffy EW, Ramsey DA, Brown TR. Structural Brain Changes following Long-Term 6? Head-Down Tilt Bed Rest as an Analog for Spaceflight. AJNR Am J Neuroradiol. 2015 Nov; 36(11):2048-54. PMID: 26185326; PMCID: PMC7964872.
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    2. Blum S, Luchsinger JA, Manly JJ, Schupf N, Stern Y, Brown TR, DeCarli C, Small SA, Mayeux R, Brickman AM, Blum S, Luchsinger JA, Manly JJ, Schupf N, Stern Y, Brown TR, DeCarli C, Small SA, Mayeux R, Brickman AM. Memory after silent stroke: hippocampus and infarcts both matter. Neurology. 2012 Jan 03; 78(1):38-46. PMID: 22201111; PMCID: PMC3466498.
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    3. Taei-Tehrani MR, Van Osch MJ, Brown TR, Taei-Tehrani MR, Van Osch MJ, Brown TR. Pseudo-random arterial modulation (PRAM): a novel arterial spin labeling approach to measure flow and blood transit times. J Magn Reson Imaging. 2012 Jan; 35(1):223-8. PMID: 21990142.
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    4. Cheung JS, Au WY, Ha SY, Kim D, Jensen JH, Zhou IY, Cheung MM, Wu Y, Guo H, Khong PL, Brown TR, Brittenham GM, Wu EX, Cheung JS, Au WY, Ha SY, Kim D, Jensen JH, Zhou IY, Cheung MM, Wu Y, Guo H, Khong PL, Brown TR, Brittenham GM, Wu EX. Reduced transverse relaxation rate (RR2) for improved sensitivity in monitoring myocardial iron in thalassemia. J Magn Reson Imaging. 2011 Jun; 33(6):1510-6. PMID: 21591022; PMCID: PMC3098046.
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    5. Debettencourt M, Goldman R, Brown T, Sajda P, Debettencourt M, Goldman R, Brown T, Sajda P. Adaptive Thresholding for Improving Sensitivity in Single-Trial Simultaneous EEG/fMRI. Front Psychol. 2011; 2:91. PMID: 21779255; PMCID: PMC3132672.
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    6. Ooi MB, Krueger S, Muraskin J, Thomas WJ, Brown TR, Ooi MB, Krueger S, Muraskin J, Thomas WJ, Brown TR. Echo-planar imaging with prospective slice-by-slice motion correction using active markers. Magn Reson Med. 2011 Jul; 66(1):73-81. PMID: 21695720; PMCID: PMC3122130.
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    7. Chen C, Brenner DJ, Brown TR, Chen C, Brenner DJ, Brown TR. Identification of urinary biomarkers from X-irradiated mice using NMR spectroscopy. Radiat Res. 2011 May; 175(5):622-30. PMID: 21338244.
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    8. Orr RK, Hoehn JL, Col NF, Wu EX, Kim D, Tosti CL, Tang H, Jensen JH, Cheung JS, Feng L, Au WY, Ha SY, Sheth SS, Brown TR, Brittenham GM. Magnetic resonance assessment of iron overload by separate measurement of tissue ferritin and hemosiderin iron. Ann N Y Acad Sci. 2010 Aug; 1202:115-22. PMID: 20712781; PMCID: PMC2943673.
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    9. Jensen JH, Tang H, Tosti CL, Swaminathan SV, Nunez A, Hultman K, Szulc KU, Wu EX, Kim D, Sheth S, Brown TR, Brittenham GM, Jensen JH, Tang H, Tosti CL, Swaminathan SV, Nunez A, Hultman K, Szulc KU, Wu EX, Kim D, Sheth S, Brown TR, Brittenham GM. Separate MRI quantification of dispersed (ferritin-like) and aggregated (hemosiderin-like) storage iron. Magn Reson Med. 2010 May; 63(5):1201-9. PMID: 20432291; PMCID: PMC2943155.
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    10. Brickman AM, Reitz C, Luchsinger JA, Manly JJ, Schupf N, Muraskin J, DeCarli C, Brown TR, Mayeux R, Brickman AM, Reitz C, Luchsinger JA, Manly JJ, Schupf N, Muraskin J, DeCarli C, Brown TR, Mayeux R. Long-term blood pressure fluctuation and cerebrovascular disease in an elderly cohort. Arch Neurol. 2010 May; 67(5):564-9. PMID: 20457955; PMCID: PMC2917204.
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    11. Brickman AM, Siedlecki KL, Muraskin J, Manly JJ, Luchsinger JA, Yeung LK, Brown TR, DeCarli C, Stern Y, Brickman AM, Siedlecki KL, Muraskin J, Manly JJ, Luchsinger JA, Yeung LK, Brown TR, DeCarli C, Stern Y. White matter hyperintensities and cognition: testing the reserve hypothesis. Neurobiol Aging. 2011 Sep; 32(9):1588-98. PMID: 19926168; PMCID: PMC2891625.
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    12. Reitz C, Brickman AM, Brown TR, Manly J, DeCarli C, Small SA, Mayeux R, Reitz C, Brickman AM, Brown TR, Manly J, DeCarli C, Small SA, Mayeux R. Linking hippocampal structure and function to memory performance in an aging population. Arch Neurol. 2009 Nov; 66(11):1385-92. PMID: 19901171; PMCID: PMC2778802.
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    13. Ooi MB, Krueger S, Thomas WJ, Swaminathan SV, Brown TR, Ooi MB, Krueger S, Thomas WJ, Swaminathan SV, Brown TR. Prospective real-time correction for arbitrary head motion using active markers. Magn Reson Med. 2009 Oct; 62(4):943-54. PMID: 19488989; PMCID: PMC3033410.
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    14. Looareesuwan S, Laothamatas J, Brown TR, Brittenham GM, Looareesuwan S, Laothamatas J, Brown TR, Brittenham GM. Cerebral malaria: a new way forward with magnetic resonance imaging (MRI). Am J Trop Med Hyg. 2009 Oct; 81(4):545-7. PMID: 19815861.
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    15. Asllani I, Habeck C, Borogovac A, Brown TR, Brickman AM, Stern Y, Asllani I, Habeck C, Borogovac A, Brown TR, Brickman AM, Stern Y. Separating function from structure in perfusion imaging of the aging brain. Hum Brain Mapp. 2009 Sep; 30(9):2927-35. PMID: 19172645; PMCID: PMC2733928.
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    16. Luchsinger JA, Brickman AM, Reitz C, Cho SJ, Schupf N, Manly JJ, Tang MX, Small SA, Mayeux R, DeCarli C, Brown TR, Luchsinger JA, Brickman AM, Reitz C, Cho SJ, Schupf N, Manly JJ, Tang MX, Small SA, Mayeux R, DeCarli C, Brown TR. Subclinical cerebrovascular disease in mild cognitive impairment. Neurology. 2009 Aug 11; 73(6):450-6. PMID: 19667320; PMCID: PMC2727144.
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    17. Guo H, Au WY, Cheung JS, Kim D, Jensen JH, Khong PL, Chan Q, Chan KC, Tosti C, Tang H, Brown TR, Lam WW, Ha SY, Brittenham GM, Wu EX, Guo H, Au WY, Cheung JS, Kim D, Jensen JH, Khong PL, Chan Q, Chan KC, Tosti C, Tang H, Brown TR, Lam WW, Ha SY, Brittenham GM, Wu EX. Myocardial T2 quantitation in patients with iron overload at 3 Tesla. J Magn Reson Imaging. 2009 Aug; 30(2):394-400. PMID: 19629983; PMCID: PMC2946793.
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    18. Reitz C, Schupf N, Luchsinger JA, Brickman AM, Manly JJ, Andrews H, Tang MX, DeCarli C, Brown TR, Mayeux R, Reitz C, Schupf N, Luchsinger JA, Brickman AM, Manly JJ, Andrews H, Tang MX, DeCarli C, Brown TR, Mayeux R. Validity of self-reported stroke in elderly African Americans, Caribbean Hispanics, and Whites. Arch Neurol. 2009 Jul; 66(7):834-40. PMID: 19433651; PMCID: PMC2881576.
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    19. Goldman RI, Wei CY, Philiastides MG, Gerson AD, Friedman D, Brown TR, Sajda P, Goldman RI, Wei CY, Philiastides MG, Gerson AD, Friedman D, Brown TR, Sajda P. Single-trial discrimination for integrating simultaneous EEG and fMRI: identifying cortical areas contributing to trial-to-trial variability in the auditory oddball task. Neuroimage. 2009 Aug 01; 47(1):136-47. PMID: 19345734; PMCID: PMC2789455.
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    20. Friedman D, Goldman R, Stern Y, Brown TR, Friedman D, Goldman R, Stern Y, Brown TR. The brain's orienting response: An event-related functional magnetic resonance imaging investigation. Hum Brain Mapp. 2009 Apr; 30(4):1144-54. PMID: 18465750; PMCID: PMC2718677.
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    21. Dyrholm M, Goldman R, Sajda P, Brown TR, Dyrholm M, Goldman R, Sajda P, Brown TR. Removal of BCG artifacts using a non-Kirchhoffian overcomplete representation. IEEE Trans Biomed Eng. 2009 Feb; 56(2):200-4. PMID: 19342324; PMCID: PMC2665919.
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    22. Duan Y, Peterson BS, Liu F, Brown TR, Ibrahim TS, Kangarlu A, Duan Y, Peterson BS, Liu F, Brown TR, Ibrahim TS, Kangarlu A. Computational and experimental optimization of a double-tuned (1)H/(31)P four-ring birdcage head coil for MRS at 3T. J Magn Reson Imaging. 2009 Jan; 29(1):13-22. PMID: 19097097.
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    23. Asllani I, Borogovac A, Brown TR, Asllani I, Borogovac A, Brown TR. Regression algorithm correcting for partial volume effects in arterial spin labeling MRI. Magn Reson Med. 2008 Dec; 60(6):1362-71. PMID: 18828149.
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    24. Louis ED, Brickman AM, DeCarli C, Small SA, Marder K, Schupf N, Brown TR, Louis ED, Brickman AM, DeCarli C, Small SA, Marder K, Schupf N, Brown TR. Quantitative brain measurements in community-dwelling elderly persons with mild parkinsonian signs. Arch Neurol. 2008 Dec; 65(12):1649-54. PMID: 19064753; PMCID: PMC2676900.
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    25. Devanand DP, Tabert MH, Cuasay K, Manly JJ, Schupf N, Brickman AM, Andrews H, Brown TR, DeCarli C, Mayeux R, Devanand DP, Tabert MH, Cuasay K, Manly JJ, Schupf N, Brickman AM, Andrews H, Brown TR, DeCarli C, Mayeux R. Olfactory identification deficits and MCI in a multi-ethnic elderly community sample. Neurobiol Aging. 2010 Sep; 31(9):1593-600. PMID: 18963256; PMCID: PMC2947189.
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    26. Lee WN, Qian Z, Tosti CL, Brown TR, Metaxas DN, Konofagou EE, Lee WN, Qian Z, Tosti CL, Brown TR, Metaxas DN, Konofagou EE. Preliminary validation of angle-independent myocardial elastography using MR tagging in a clinical setting. Ultrasound Med Biol. 2008 Dec; 34(12):1980-97. PMID: 18952364; PMCID: PMC4124643.
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    27. Brickman AM, Schupf N, Manly JJ, Luchsinger JA, Andrews H, Tang MX, Reitz C, Small SA, Mayeux R, DeCarli C, Brown TR, Brickman AM, Schupf N, Manly JJ, Luchsinger JA, Andrews H, Tang MX, Reitz C, Small SA, Mayeux R, DeCarli C, Brown TR. Brain morphology in older African Americans, Caribbean Hispanics, and whites from northern Manhattan. Arch Neurol. 2008 Aug; 65(8):1053-61. PMID: 18695055; PMCID: PMC2692286.
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    28. Choi JJ, Wang S, Brown TR, Small SA, Duff KE, Konofagou EE, Choi JJ, Wang S, Brown TR, Small SA, Duff KE, Konofagou EE. Noninvasive and transient blood-brain barrier opening in the hippocampus of Alzheimer's double transgenic mice using focused ultrasound. Ultrason Imaging. 2008 Jul; 30(3):189-200. PMID: 19149463; PMCID: PMC3919133.
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    29. Hultman KL, Raffo AJ, Grzenda AL, Harris PE, Brown TR, O'Brien S, Hultman KL, Raffo AJ, Grzenda AL, Harris PE, Brown TR, O'Brien S. Magnetic resonance imaging of major histocompatibility class II expression in the renal medulla using immunotargeted superparamagnetic iron oxide nanoparticles. ACS Nano. 2008 Mar; 2(3):477-84. PMID: 19206573.
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    30. Wright CB, Festa JR, Paik MC, Schmiedigen A, Brown TR, Yoshita M, DeCarli C, Sacco R, Stern Y, Wright CB, Festa JR, Paik MC, Schmiedigen A, Brown TR, Yoshita M, DeCarli C, Sacco R, Stern Y. White matter hyperintensities and subclinical infarction: associations with psychomotor speed and cognitive flexibility. Stroke. 2008 Mar; 39(3):800-5. PMID: 18258844; PMCID: PMC2267752.
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    31. Sigmund EE, Cho H, Chen P, Byrnes S, Song YQ, Guo XE, Brown TR, Sigmund EE, Cho H, Chen P, Byrnes S, Song YQ, Guo XE, Brown TR. Diffusion-based MR methods for bone structure and evolution. Magn Reson Med. 2008 Jan; 59(1):28-39. PMID: 18098292.
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    32. Asllani I, Borogovac A, Wright C, Sacco R, Brown TR, Zarahn E, Asllani I, Borogovac A, Wright C, Sacco R, Brown TR, Zarahn E. An investigation of statistical power for continuous arterial spin labeling imaging at 1.5 T. Neuroimage. 2008 Feb 01; 39(3):1246-56. PMID: 18036834; PMCID: PMC2665307.
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    33. Asllani I, Habeck C, Scarmeas N, Borogovac A, Brown TR, Stern Y, Asllani I, Habeck C, Scarmeas N, Borogovac A, Brown TR, Stern Y. Multivariate and univariate analysis of continuous arterial spin labeling perfusion MRI in Alzheimer's disease. J Cereb Blood Flow Metab. 2008 Apr; 28(4):725-36. PMID: 17960142; PMCID: PMC2711077.
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    34. Moreno H, Wu WE, Lee T, Brickman A, Mayeux R, Brown TR, Small SA, Moreno H, Wu WE, Lee T, Brickman A, Mayeux R, Brown TR, Small SA. Imaging the Abeta-related neurotoxicity of Alzheimer disease. Arch Neurol. 2007 Oct; 64(10):1467-77. PMID: 17923630.
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    35. Choi JJ, Pernot M, Brown TR, Small SA, Konofagou EE, Choi JJ, Pernot M, Brown TR, Small SA, Konofagou EE. Spatio-temporal analysis of molecular delivery through the blood-brain barrier using focused ultrasound. Phys Med Biol. 2007 Sep 21; 52(18):5509-30. PMID: 17804879.
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    36. Pereira AC, Huddleston DE, Brickman AM, Sosunov AA, Hen R, McKhann GM, Sloan R, Gage FH, Brown TR, Small SA, Pereira AC, Huddleston DE, Brickman AM, Sosunov AA, Hen R, McKhann GM, Sloan R, Gage FH, Brown TR, Small SA. An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus. Proc Natl Acad Sci U S A. 2007 Mar 27; 104(13):5638-43. PMID: 17374720; PMCID: PMC1838482.
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    37. Tabert MH, Steffener J, Albers MW, Kern DW, Michael M, Tang H, Brown TR, Devanand DP, Tabert MH, Steffener J, Albers MW, Kern DW, Michael M, Tang H, Brown TR, Devanand DP. Validation and optimization of statistical approaches for modeling odorant-induced fMRI signal changes in olfactory-related brain areas. Neuroimage. 2007 Feb 15; 34(4):1375-90. PMID: 17196831.
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    38. Zhao Q, Stoyanova R, Du S, Sajda P, Brown TR, Zhao Q, Stoyanova R, Du S, Sajda P, Brown TR. HiRes--a tool for comprehensive assessment and interpretation of metabolomic data. Bioinformatics. 2006 Oct 15; 22(20):2562-4. PMID: 16895927.
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    39. Arias-Mendoza F, Payne GS, Zakian KL, Schwarz AJ, Stubbs M, Stoyanova R, Ballon D, Howe FA, Koutcher JA, Leach MO, Griffiths JR, Heerschap A, Glickson JD, Nelson SJ, Evelhoch JL, Charles HC, Brown TR, Arias-Mendoza F, Payne GS, Zakian KL, Schwarz AJ, Stubbs M, Stoyanova R, Ballon D, Howe FA, Koutcher JA, Leach MO, Griffiths JR, Heerschap A, Glickson JD, Nelson SJ, Evelhoch JL, Charles HC, Brown TR. In vivo 31P MR spectral patterns and reproducibility in cancer patients studied in a multi-institutional trial. NMR Biomed. 2006 Jun; 19(4):504-12. PMID: 16763965.
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    40. Coon AL, Arias-Mendoza F, Colby GP, Cruz-Lobo J, Mocco J, Mack WJ, Komotar RJ, Brown TR, Connolly ES, Coon AL, Arias-Mendoza F, Colby GP, Cruz-Lobo J, Mocco J, Mack WJ, Komotar RJ, Brown TR, Connolly ES. Correlation of cerebral metabolites with functional outcome in experimental primate stroke using in vivo 1H-magnetic resonance spectroscopy. AJNR Am J Neuroradiol. 2006 May; 27(5):1053-8. PMID: 16687542; PMCID: PMC7975755.
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    41. Wright CB, Paik MC, Brown TR, Stabler SP, Allen RH, Sacco RL, DeCarli C, Wright CB, Paik MC, Brown TR, Stabler SP, Allen RH, Sacco RL, DeCarli C. Total homocysteine is associated with white matter hyperintensity volume: the Northern Manhattan Study. Stroke. 2005 Jun; 36(6):1207-11. PMID: 15879345; PMCID: PMC1352322.
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    42. Sheth S, Tang H, Jensen JH, Altmann K, Prakash A, Printz BF, Hordof AJ, Tosti CL, Azabagic A, Swaminathan S, Brown TR, Olivieri NF, Brittenham GM, Sheth S, Tang H, Jensen JH, Altmann K, Prakash A, Printz BF, Hordof AJ, Tosti CL, Azabagic A, Swaminathan S, Brown TR, Olivieri NF, Brittenham GM. Methods for noninvasive measurement of tissue iron in Cooley's anemia. Ann N Y Acad Sci. 2005; 1054:358-72. PMID: 16339684.
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    43. Sajda P, Du S, Brown TR, Stoyanova R, Shungu DC, Mao X, Parra LC, Sajda P, Du S, Brown TR, Stoyanova R, Shungu DC, Mao X, Parra LC. Nonnegative matrix factorization for rapid recovery of constituent spectra in magnetic resonance chemical shift imaging of the brain. IEEE Trans Med Imaging. 2004 Dec; 23(12):1453-65. PMID: 15575404.
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    44. Robinson JN, Cleary-Goldman J, Arias-Mendoza F, Cruz-Lobo J, Tempany C, Mulkern RV, Feinberg BB, Brown TR, Robinson JN, Cleary-Goldman J, Arias-Mendoza F, Cruz-Lobo J, Tempany C, Mulkern RV, Feinberg BB, Brown TR. Detection of fetal lactate with two-dimensional-localized proton magnetic resonance spectroscopy. Obstet Gynecol. 2004 Nov; 104(5 Pt 2):1208-10. PMID: 15516455.
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    45. Arias-Mendoza F, Zakian K, Schwartz A, Howe FA, Koutcher JA, Leach MO, Griffiths JR, Heerschap A, Glickson JD, Nelson SJ, Evelhoch JL, Charles HC, Brown TR, Arias-Mendoza F, Zakian K, Schwartz A, Howe FA, Koutcher JA, Leach MO, Griffiths JR, Heerschap A, Glickson JD, Nelson SJ, Evelhoch JL, Charles HC, Brown TR, Cooperative Group on MRS Applications in Cancer. Methodological standardization for a multi-institutional in vivo trial of localized 31P MR spectroscopy in human cancer research. In vitro and normal volunteer studies. NMR Biomed. 2004 Oct; 17(6):382-91. PMID: 15386624.
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    46. Stoyanova R, Nicholls AW, Nicholson JK, Lindon JC, Brown TR, Stoyanova R, Nicholls AW, Nicholson JK, Lindon JC, Brown TR. Automatic alignment of individual peaks in large high-resolution spectral data sets. J Magn Reson. 2004 Oct; 170(2):329-35. PMID: 15388097.
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    47. Stoyanova R, Nicholson JK, Lindon JC, Brown TR, Stoyanova R, Nicholson JK, Lindon JC, Brown TR. Sample classification based on Bayesian spectral decomposition of metabonomic NMR data sets. Anal Chem. 2004 Jul 01; 76(13):3666-74. PMID: 15228339.
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    48. Arias-Mendoza F, Smith MR, Brown TR, Arias-Mendoza F, Smith MR, Brown TR. Predicting treatment response in non-Hodgkin's lymphoma from the pretreatment tumor content of phosphoethanolamine plus phosphocholine. Acad Radiol. 2004 Apr; 11(4):368-76. PMID: 15109009.
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    49. Stoyanova R, Querec TD, Brown TR, Patriotis C, Stoyanova R, Querec TD, Brown TR, Patriotis C. Normalization of single-channel DNA array data by principal component analysis. Bioinformatics. 2004 Jul 22; 20(11):1772-84. PMID: 15037508.
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    50. Orr RK, Hoehn JL, Col NF, Brown TR, Su B, Brown KA, Schwartz MA, Tobia AM, Kappler F. Modulation of in vivo 3-deoxyglucosone levels. Biochem Soc Trans. 2003 Dec; 31(Pt 6):1433-7. PMID: 14641082.
      Citations: 3     Fields:    Translation:Animals
    51. Arias-Mendoza F, Brown TR, Arias-Mendoza F, Brown TR. In vivo measurement of phosphorous markers of disease. Dis Markers. 2003-2004; 19(2-3):49-68. PMID: 15096705; PMCID: PMC3851420.
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    52. Franks SE, Smith MR, Arias-Mendoza F, Shaller C, Padavic-Shaller K, Kappler F, Zhang Y, Negendank WG, Brown TR, Franks SE, Smith MR, Arias-Mendoza F, Shaller C, Padavic-Shaller K, Kappler F, Zhang Y, Negendank WG, Brown TR. Phosphomonoester concentrations differ between chronic lymphocytic leukemia cells and normal human lymphocytes. Leuk Res. 2002 Oct; 26(10):919-26. PMID: 12163053.
      Citations: 12     Fields:    Translation:HumansCells
    53. Shukla-Dave A, Poptani H, Loevner LA, Mancuso A, Serrai H, Rosenthal DI, Kilger AM, Nelson DS, Zakian KL, Arias-Mendoza F, Rijpkema M, Koutcher JA, Brown TR, Heerschap A, Glickson JD, Shukla-Dave A, Poptani H, Loevner LA, Mancuso A, Serrai H, Rosenthal DI, Kilger AM, Nelson DS, Zakian KL, Arias-Mendoza F, Rijpkema M, Koutcher JA, Brown TR, Heerschap A, Glickson JD. Prediction of treatment response of head and neck cancers with P-31 MR spectroscopy from pretreatment relative phosphomonoester levels. Acad Radiol. 2002 Jun; 9(6):688-94. PMID: 12061743.
      Citations:    
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