Connection

Philip Howe to Humans

This is a "connection" page, showing publications Philip Howe has written about Humans.
Connection Strength

0.584
  1. The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression. Oncogene. 2022 03; 41(12):1679-1690.
    View in: PubMed
    Score: 0.030
  2. TGF?-induced expression of long noncoding lincRNA Platr18 controls breast cancer axonogenesis. Life Sci Alliance. 2022 02; 5(2).
    View in: PubMed
    Score: 0.030
  3. Heterogeneous nuclear ribonucleoprotein E1 binds polycytosine DNA and monitors genome integrity. Life Sci Alliance. 2021 09; 4(9).
    View in: PubMed
    Score: 0.029
  4. TGF? promotes breast cancer stem cell self-renewal through an ILEI/LIFR signaling axis. Oncogene. 2019 05; 38(20):3794-3811.
    View in: PubMed
    Score: 0.024
  5. Interleukin-like EMT inducer (ILEI) promotes melanoma invasiveness and is transcriptionally up-regulated by upstream stimulatory factor-1 (USF-1). J Biol Chem. 2018 07 20; 293(29):11401-11414.
    View in: PubMed
    Score: 0.023
  6. TGF-beta signaling in cancer: post-transcriptional regulation of EMT via hnRNP E1. Cytokine. 2019 06; 118:19-26.
    View in: PubMed
    Score: 0.023
  7. EMT does not work regular shifts. Cell Cycle. 2018; 17(2):141-142.
    View in: PubMed
    Score: 0.023
  8. A CREB3-regulated ER-Golgi trafficking signature promotes metastatic progression in breast cancer. Oncogene. 2018 03; 37(10):1308-1325.
    View in: PubMed
    Score: 0.023
  9. A regulated PNUTS mRNA to lncRNA splice switch mediates EMT and tumour progression. Nat Cell Biol. 2017 Sep; 19(9):1105-1115.
    View in: PubMed
    Score: 0.022
  10. Interleukin-like EMT inducer regulates partial phenotype switching in MITF-low melanoma cell lines. PLoS One. 2017; 12(5):e0177830.
    View in: PubMed
    Score: 0.022
  11. Cathepsin-B-mediated cleavage of Disabled-2 regulates TGF-?-induced autophagy. Nat Cell Biol. 2016 08; 18(8):851-63.
    View in: PubMed
    Score: 0.020
  12. PCBP1/HNRNP E1 Protects Chromosomal Integrity by Translational Regulation of CDC27. Mol Cancer Res. 2016 07; 14(7):634-46.
    View in: PubMed
    Score: 0.020
  13. Identification and characterization of an hnRNP E1 translational silencing motif. Nucleic Acids Res. 2016 07 08; 44(12):5892-907.
    View in: PubMed
    Score: 0.020
  14. 3'-UTR-mediated post-transcriptional regulation of cancer metastasis: beginning at the end. RNA Biol. 2011 Jul-Aug; 8(4):595-9.
    View in: PubMed
    Score: 0.014
  15. Discovery of a metastatic pathway: implications for future cancer treatment. Future Oncol. 2011 Jun; 7(6):703-5.
    View in: PubMed
    Score: 0.014
  16. Heterogeneous nuclear ribonucleoproteins (hnRNPs) in cellular processes: Focus on hnRNP E1's multifunctional regulatory roles. RNA. 2010 Aug; 16(8):1449-62.
    View in: PubMed
    Score: 0.013
  17. The tale of transforming growth factor-beta (TGFbeta) signaling: a soign? enigma. IUBMB Life. 2009 Oct; 61(10):929-39.
    View in: PubMed
    Score: 0.013
  18. Runx1 is a co-activator with FOXO3 to mediate transforming growth factor beta (TGFbeta)-induced Bim transcription in hepatic cells. J Biol Chem. 2009 Jul 24; 284(30):20227-39.
    View in: PubMed
    Score: 0.012
  19. Transforming growth factor beta (TGFbeta)-induced apoptosis: the rise & fall of Bim. Cell Cycle. 2009 Jan 01; 8(1):11-7.
    View in: PubMed
    Score: 0.012
  20. Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function. J Biol Chem. 2006 Jan 13; 281(2):813-23.
    View in: PubMed
    Score: 0.010
  21. Disabled-2 (Dab2) mediates transforming growth factor beta (TGFbeta)-stimulated fibronectin synthesis through TGFbeta-activated kinase 1 and activation of the JNK pathway. J Biol Chem. 2005 Jul 08; 280(27):25920-7.
    View in: PubMed
    Score: 0.009
  22. Wnt signaling: physiology and pathology. Growth Factors. 2004 Sep; 22(3):141-50.
    View in: PubMed
    Score: 0.009
  23. Staphylococcus aureus peptidoglycan (PGN) induces pathogenic autoantibody production via autoreactive B cell receptor clonal selection, implications in systemic lupus erythematosus. J Autoimmun. 2022 07; 131:102860.
    View in: PubMed
    Score: 0.008
  24. Smad7 is induced by CD40 and protects WEHI 231 B-lymphocytes from transforming growth factor-beta -induced growth inhibition and apoptosis. J Biol Chem. 2000 Dec 08; 275(49):38363-70.
    View in: PubMed
    Score: 0.007
  25. The role of disabled-2 (Dab2) in diseases. Gene. 2021 Feb 15; 769:145202.
    View in: PubMed
    Score: 0.007
  26. RNA binding protein PCBP1 is an intracellular immune checkpoint for shaping T cell responses in cancer immunity. Sci Adv. 2020 05; 6(22):eaaz3865.
    View in: PubMed
    Score: 0.007
  27. Analysis of TGF-beta-mediated synthesis of extracellular matrix components. Methods Mol Biol. 2000; 142:55-65.
    View in: PubMed
    Score: 0.007
  28. Promoter analysis of TGF-beta responsive genes by transient transfection and deletional/mutational analysis. Methods Mol Biol. 2000; 142:79-95.
    View in: PubMed
    Score: 0.007
  29. Regulation of AP-1 activity by TGF-beta. Methods Mol Biol. 2000; 142:97-108.
    View in: PubMed
    Score: 0.007
  30. Analysis of TGF-beta-inducible apoptosis. Methods Mol Biol. 2000; 142:149-67.
    View in: PubMed
    Score: 0.007
  31. Transforming growth factor beta regulates clusterin gene expression via modulation of transcription factor c-Fos. Eur J Biochem. 1999 Jul; 263(2):534-42.
    View in: PubMed
    Score: 0.006
  32. TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway. EMBO J. 1999 Mar 01; 18(5):1345-56.
    View in: PubMed
    Score: 0.006
  33. The Long (lncRNA) and Short (miRNA) of It: TGF?-Mediated Control of RNA-Binding Proteins and Noncoding RNAs. Mol Cancer Res. 2018 04; 16(4):567-579.
    View in: PubMed
    Score: 0.006
  34. Metabolic Labeling and Profiling of Transfer RNAs Using Macroarrays. J Vis Exp. 2018 01 16; (131).
    View in: PubMed
    Score: 0.006
  35. Mechanisms of TGF-beta-induced cell cycle arrest. Miner Electrolyte Metab. 1998; 24(2-3):131-5.
    View in: PubMed
    Score: 0.006
  36. Fbxo4-mediated degradation of Fxr1 suppresses tumorigenesis in head and neck squamous cell carcinoma. Nat Commun. 2017 11 16; 8(1):1534.
    View in: PubMed
    Score: 0.006
  37. TGF-? receptor I/II trafficking and signaling at primary cilia are inhibited by ceramide to attenuate cell migration and tumor metastasis. Sci Signal. 2017 Oct 24; 10(502).
    View in: PubMed
    Score: 0.006
  38. Regulation of clusterin gene expression by transforming growth factor beta. J Biol Chem. 1997 Oct 17; 272(42):26620-6.
    View in: PubMed
    Score: 0.006
  39. Membrane-organizing protein moesin controls Treg differentiation and antitumor immunity via TGF-? signaling. J Clin Invest. 2017 Apr 03; 127(4):1321-1337.
    View in: PubMed
    Score: 0.005
  40. S.?pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity. Mol Cell. 2017 Feb 16; 65(4):699-714.e6.
    View in: PubMed
    Score: 0.005
  41. Repression of caspase-3 and RNA-binding protein HuR cleavage by cyclooxygenase-2 promotes drug resistance in oral squamous cell carcinoma. Oncogene. 2017 06 01; 36(22):3137-3148.
    View in: PubMed
    Score: 0.005
  42. Surface Expression of TGF? Docking Receptor GARP Promotes Oncogenesis and Immune Tolerance in Breast Cancer. Cancer Res. 2016 12 15; 76(24):7106-7117.
    View in: PubMed
    Score: 0.005
  43. Isolation and characterization of mutant cell lines defective in transforming growth factor beta signaling. Proc Natl Acad Sci U S A. 1996 Jul 23; 93(15):7655-60.
    View in: PubMed
    Score: 0.005
  44. The La protein counteracts cisplatin-induced cell death by stimulating protein synthesis of anti-apoptotic factor Bcl2. Oncotarget. 2016 May 17; 7(20):29664-76.
    View in: PubMed
    Score: 0.005
  45. Transforming growth factor beta (TGF beta)-induced nuclear localization of apolipoprotein J/clusterin in epithelial cells. Biochemistry. 1996 May 14; 35(19):6157-63.
    View in: PubMed
    Score: 0.005
  46. Transforming Growth Factor-? Is an Upstream Regulator of Mammalian Target of Rapamycin Complex 2-Dependent Bladder Cancer Cell Migration and Invasion. Am J Pathol. 2016 05; 186(5):1351-60.
    View in: PubMed
    Score: 0.005
  47. Interaction of transforming growth factor beta receptors with apolipoprotein J/clusterin. Biochemistry. 1996 Jan 09; 35(1):309-14.
    View in: PubMed
    Score: 0.005
  48. Neuropilin-2 Is upregulated in lung cancer cells during TGF-?1-induced epithelial-mesenchymal transition. Cancer Res. 2013 Dec 01; 73(23):7111-21.
    View in: PubMed
    Score: 0.004
  49. Transforming growth factor beta 1-mediated inhibition of smooth muscle cell proliferation is associated with a late G1 cell cycle arrest. J Cell Physiol. 1993 Jul; 156(1):48-55.
    View in: PubMed
    Score: 0.004
  50. HOXA9 participates in the transcriptional activation of E-selectin in endothelial cells. Mol Cell Biol. 2007 Jun; 27(12):4207-16.
    View in: PubMed
    Score: 0.003
  51. Role of CL-100, a dual specificity phosphatase, in thrombin-induced endothelial cell activation. J Biol Chem. 2004 Nov 05; 279(45):46678-85.
    View in: PubMed
    Score: 0.002
  52. The retinoid antagonist MX781 induces clusterin expression in prostate cancer cells via heat shock factor-1 and activator protein-1 transcription factors. Cancer Res. 2004 Aug 15; 64(16):5905-12.
    View in: PubMed
    Score: 0.002
  53. Secreted transforming growth factor beta2 activates NF-kappaB, blocks apoptosis, and is essential for the survival of some tumor cells. Proc Natl Acad Sci U S A. 2004 May 04; 101(18):7112-7.
    View in: PubMed
    Score: 0.002
  54. TGF-beta suppresses IFN-gamma induction of class II MHC gene expression by inhibiting class II transactivator messenger RNA expression. J Immunol. 1997 Mar 01; 158(5):2065-75.
    View in: PubMed
    Score: 0.001
  55. Inhibition of interferon-gamma-induced major histocompatibility complex class II gene transcription by interferon-beta and type beta 1 transforming growth factor in human astrocytoma cells. Definition of cis-element. J Biol Chem. 1993 Sep 05; 268(25):18794-800.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.