Connection

Dariusz Pytel to Humans

This is a "connection" page, showing publications Dariusz Pytel has written about Humans.
Connection Strength

0.253
  1. PERK Is a Haploinsufficient Tumor Suppressor: Gene Dose Determines Tumor-Suppressive Versus Tumor Promoting Properties of PERK in Melanoma. PLoS Genet. 2016 Dec; 12(12):e1006518.
    View in: PubMed
    Score: 0.022
  2. Enzymatic Characterization of ER Stress-Dependent Kinase, PERK, and Development of a High-Throughput Assay for Identification of PERK Inhibitors. J Biomol Screen. 2014 Aug; 19(7):1024-34.
    View in: PubMed
    Score: 0.018
  3. Tyrosine kinase blockers: new hope for successful cancer therapy. Anticancer Agents Med Chem. 2009 Jan; 9(1):66-76.
    View in: PubMed
    Score: 0.013
  4. [Uracil-DNA glycosylases]. Postepy Biochem. 2008; 54(4):362-70.
    View in: PubMed
    Score: 0.012
  5. Comparative study of DNA damage, cell cycle and apoptosis in human K562 and CCRF-CEM leukemia cells: role of BCR/ABL in therapeutic resistance. Comp Biochem Physiol C Toxicol Pharmacol. 2006 Sep; 144(1):85-92.
    View in: PubMed
    Score: 0.011
  6. Tumor suppressor mediated ubiquitylation of hnRNPK is a barrier to oncogenic translation. Nat Commun. 2022 11 03; 13(1):6614.
    View in: PubMed
    Score: 0.008
  7. Carbon Monoxide Activates PERK-Regulated Autophagy to Induce Immunometabolic Reprogramming and Boost Antitumor T-cell Function. Cancer Res. 2022 05 16; 82(10):1969-1990.
    View in: PubMed
    Score: 0.008
  8. Small-molecule inhibitors of the PERK-mediated Unfolded Protein Response signaling pathway in targeted therapy for colorectal cancer. Pol Przegl Chir. 2022 Mar 15; 94(6):17-25.
    View in: PubMed
    Score: 0.008
  9. The Potential Role of Small-Molecule PERK Inhibitor LDN-0060609 in Primary Open-Angle Glaucoma Treatment. Int J Mol Sci. 2021 Apr 26; 22(9).
    View in: PubMed
    Score: 0.008
  10. The PERK-Dependent Molecular Mechanisms as a Novel Therapeutic Target for Neurodegenerative Diseases. Int J Mol Sci. 2020 Mar 19; 21(6).
    View in: PubMed
    Score: 0.007
  11. Use of Small-molecule Inhibitory Compound of PERK-dependent Signaling Pathway as a Promising Target-based Therapy for Colorectal Cancer. Curr Cancer Drug Targets. 2020; 20(3):223-238.
    View in: PubMed
    Score: 0.007
  12. Dual role of Endoplasmic Reticulum Stress-Mediated Unfolded Protein Response Signaling Pathway in Carcinogenesis. Int J Mol Sci. 2019 Sep 05; 20(18).
    View in: PubMed
    Score: 0.007
  13. Potential therapeutic application of PERK inhibitors Postepy Biochem. 2019 06 06; 65(2):118-127.
    View in: PubMed
    Score: 0.007
  14. Interplay between Redox Signaling, Oxidative Stress, and Unfolded Protein Response (UPR) in Pathogenesis of Human Diseases. Oxid Med Cell Longev. 2019; 2019:6949347.
    View in: PubMed
    Score: 0.007
  15. [Niskoczasteczkowe inhibitory szlaku adaptacyjnej odpowiedzi na stres zaleznego od kinazy PERK jako nowatorska strategia terapeutyczna w leczeniu choroby Alzheimera]. Pol Merkur Lekarski. 2019 Jan 28; 46(271):9-15.
    View in: PubMed
    Score: 0.006
  16. Breaking the DNA Damage Response via Serine/Threonine Kinase Inhibitors to Improve Cancer Treatment. Curr Med Chem. 2019; 26(8):1425-1445.
    View in: PubMed
    Score: 0.006
  17. Induction of apoptosis in human glioma cell lines of various grades through the ROS-mediated mitochondrial pathway and caspase activation by Rhaponticum carthamoides transformed root extract. Mol Cell Biochem. 2018 Aug; 445(1-2):89-97.
    View in: PubMed
    Score: 0.006
  18. Inhibition of PERK-dependent pro-adaptive signaling pathway as a promising approach for cancer treatment. Pol Przegl Chir. 2017 Jun 30; 89(3):7-10.
    View in: PubMed
    Score: 0.006
  19. Antibacterial, Anti-Inflammatory, Antioxidant, and Antiproliferative Properties of Essential Oils from Hairy and Normal Roots of Leonurus sibiricus L. and Their Chemical Composition. Oxid Med Cell Longev. 2017; 2017:7384061.
    View in: PubMed
    Score: 0.006
  20. Nucleotide Excision Repair Capacity and XPC and XPD Gene Polymorphism Modulate Colorectal Cancer Risk. Clin Colorectal Cancer. 2018 06; 17(2):e435-e441.
    View in: PubMed
    Score: 0.006
  21. The Essential Oils of Rhaponticum carthamoides Hairy Roots and Roots of Soil-Grown Plants: Chemical Composition and Antimicrobial, Anti-Inflammatory, and Antioxidant Activities. Oxid Med Cell Longev. 2016; 2016:8505384.
    View in: PubMed
    Score: 0.006
  22. [Small molecule inhibitors of PERK-dependent signaling pathway as a novel, therapeutic molecular strategy in Alzheimer's disease treatment]. Pol Merkur Lekarski. 2016 Jul 29; 41(241):5-10.
    View in: PubMed
    Score: 0.005
  23. [The role of the adaptive stress response in the pathogenesis of neurodegenerative diseases, cancer and diabetes mellitus type 2]. Pol Merkur Lekarski. 2015 Dec; 39(234):393-7.
    View in: PubMed
    Score: 0.005
  24. The role of base excision repair in pathogenesis of breast cancer in the Polish population. Mol Carcinog. 2016 12; 55(12):1899-1914.
    View in: PubMed
    Score: 0.005
  25. The role of base excision repair in the development of primary open angle glaucoma in the Polish population. Mutat Res. 2015 Aug; 778:26-40.
    View in: PubMed
    Score: 0.005
  26. Altered Expression Levels of MMP1, MMP9, MMP12, TIMP1, and IL-1? as a Risk Factor for the Elevated IOP and Optic Nerve Head Damage in the Primary Open-Angle Glaucoma Patients. Biomed Res Int. 2015; 2015:812503.
    View in: PubMed
    Score: 0.005
  27. Analysis of the expression and polymorphism of APOE, HSP, BDNF, and GRIN2B genes associated with the neurodegeneration process in the pathogenesis of primary open angle glaucoma. Biomed Res Int. 2015; 2015:258281.
    View in: PubMed
    Score: 0.005
  28. Unfolded Protein Response and PERK Kinase as a New Therapeutic Target in the Pathogenesis of Alzheimer's Disease. Curr Med Chem. 2015; 22(27):3169-84.
    View in: PubMed
    Score: 0.005
  29. The ? isoform of diacylglycerol kinase plays a predominant role in regulatory T cell development and TCR-mediated ras signaling. Sci Signal. 2013 Nov 26; 6(303):ra102.
    View in: PubMed
    Score: 0.004
  30. The FBXO4 tumor suppressor functions as a barrier to BRAFV600E-dependent metastatic melanoma. Mol Cell Biol. 2013 Nov; 33(22):4422-33.
    View in: PubMed
    Score: 0.004
  31. UPR-inducible miRNAs contribute to stressful situations. Trends Biochem Sci. 2013 Sep; 38(9):447-52.
    View in: PubMed
    Score: 0.004
  32. miR-211 is a prosurvival microRNA that regulates chop expression in a PERK-dependent manner. Mol Cell. 2012 Nov 09; 48(3):353-64.
    View in: PubMed
    Score: 0.004
  33. BCR/ABL stimulates WRN to promote survival and genomic instability. Cancer Res. 2011 Feb 01; 71(3):842-51.
    View in: PubMed
    Score: 0.004
  34. DNA damage and repair of head and neck cancer cells after radio- and chemotherapy. Z Naturforsch C J Biosci. 2009 Jul-Aug; 64(7-8):601-10.
    View in: PubMed
    Score: 0.003
  35. [The role of oncogenic tyrosine kinases in the cellular response to anticancer therapy]. Postepy Hig Med Dosw (Online). 2007 Dec 14; 61:819-27.
    View in: PubMed
    Score: 0.003
  36. Imatinib (STI571) inhibits DNA repair in human leukemia oncogenic tyrosine kinase-expressing cells. Z Naturforsch C J Biosci. 2006 Nov-Dec; 61(11-12):896-902.
    View in: PubMed
    Score: 0.003
  37. Imatinib mesylate (STI571) abrogates the resistance to doxorubicin in human K562 chronic myeloid leukemia cells by inhibition of BCR/ABL kinase-mediated DNA repair. Mutat Res. 2006 Jan 31; 603(1):74-82.
    View in: PubMed
    Score: 0.003
  38. [Tyrosine kinases. New target of anticancer therapy]. Postepy Biochem. 2005; 51(3):251-60.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.