Connection

Joshua Lipschutz to Animals

This is a "connection" page, showing publications Joshua Lipschutz has written about Animals.
Connection Strength

1.330
  1. Conditional Loss of the Exocyst Component Exoc5 in Retinal Pigment Epithelium (RPE) Results in RPE Dysfunction, Photoreceptor Cell Degeneration, and Decreased Visual Function. Int J Mol Sci. 2021 May 11; 22(10).
    View in: PubMed
    Score: 0.055
  2. Primary cilia and the exocyst are linked to urinary extracellular vesicle production and content. J Biol Chem. 2019 12 13; 294(50):19099-19110.
    View in: PubMed
    Score: 0.050
  3. Defects in the Exocyst-Cilia Machinery Cause Bicuspid Aortic Valve Disease and Aortic Stenosis. Circulation. 2019 10 15; 140(16):1331-1341.
    View in: PubMed
    Score: 0.049
  4. Disruption of the exocyst induces podocyte loss and dysfunction. J Biol Chem. 2019 06 28; 294(26):10104-10119.
    View in: PubMed
    Score: 0.048
  5. The exocyst acting through the primary cilium is necessary for renal ciliogenesis, cystogenesis, and tubulogenesis. J Biol Chem. 2019 04 26; 294(17):6710-6718.
    View in: PubMed
    Score: 0.047
  6. The exocyst is required for photoreceptor ciliogenesis and retinal development. J Biol Chem. 2017 09 08; 292(36):14814-14826.
    View in: PubMed
    Score: 0.042
  7. Adaptor Protein CD2AP and L-type Lectin LMAN2 Regulate Exosome Cargo Protein Trafficking through the Golgi Complex. J Biol Chem. 2016 Dec 02; 291(49):25462-25475.
    View in: PubMed
    Score: 0.040
  8. Dynamin Binding Protein (Tuba) Deficiency Inhibits Ciliogenesis and Nephrogenesis in Vitro and in Vivo. J Biol Chem. 2016 Apr 15; 291(16):8632-43.
    View in: PubMed
    Score: 0.038
  9. Urothelial Defects from Targeted Inactivation of Exocyst Sec10 in Mice Cause Ureteropelvic Junction Obstructions. PLoS One. 2015; 10(6):e0129346.
    View in: PubMed
    Score: 0.037
  10. Cdc42 and sec10 Are Required for Normal Retinal Development in Zebrafish. Invest Ophthalmol Vis Sci. 2015 May; 56(5):3361-70.
    View in: PubMed
    Score: 0.036
  11. A possible zebrafish model of polycystic kidney disease: knockdown of wnt5a causes cysts in zebrafish kidneys. J Vis Exp. 2014 Dec 02; (94).
    View in: PubMed
    Score: 0.035
  12. Wnt5a is necessary for normal kidney development in zebrafish and mice. Nephron Exp Nephrol. 2014; 128(1-2):80-8.
    View in: PubMed
    Score: 0.035
  13. Exocyst Sec10 protects renal tubule cells from injury by EGFR/MAPK activation and effects on endocytosis. Am J Physiol Renal Physiol. 2014 Dec 15; 307(12):F1334-41.
    View in: PubMed
    Score: 0.035
  14. Cilia and polycystic kidney disease, kith and kin. Birth Defects Res C Embryo Today. 2014 Jun; 102(2):174-85.
    View in: PubMed
    Score: 0.034
  15. Novel MAPK-dependent and -independent tubulogenes identified via microarray analysis of 3D-cultured Madin-Darby canine kidney cells. Am J Physiol Renal Physiol. 2014 May 01; 306(9):F1047-58.
    View in: PubMed
    Score: 0.034
  16. Expression of Drosophila forkhead transcription factors during kidney development. Biochem Biophys Res Commun. 2014 Mar 28; 446(1):15-7.
    View in: PubMed
    Score: 0.033
  17. Cdc42 deficiency causes ciliary abnormalities and cystic kidneys. J Am Soc Nephrol. 2013 Sep; 24(9):1435-50.
    View in: PubMed
    Score: 0.032
  18. Exocyst Sec10 is involved in basolateral protein translation and translocation in the endoplasmic reticulum. Nephron Exp Nephrol. 2012; 120(4):e134-40.
    View in: PubMed
    Score: 0.030
  19. The small GTPase Cdc42 is necessary for primary ciliogenesis in renal tubular epithelial cells. J Biol Chem. 2011 Jun 24; 286(25):22469-77.
    View in: PubMed
    Score: 0.028
  20. The exocyst protein Sec10 interacts with Polycystin-2 and knockdown causes PKD-phenotypes. PLoS Genet. 2011 Apr; 7(4):e1001361.
    View in: PubMed
    Score: 0.027
  21. Exocyst Sec10 protects epithelial barrier integrity and enhances recovery following oxidative stress, by activation of the MAPK pathway. Am J Physiol Renal Physiol. 2010 Mar; 298(3):F818-26.
    View in: PubMed
    Score: 0.025
  22. The exocyst protein Sec10 is necessary for primary ciliogenesis and cystogenesis in vitro. Mol Biol Cell. 2009 May; 20(10):2522-9.
    View in: PubMed
    Score: 0.024
  23. Tubule and cyst formation: lightning strikes twice. Am J Physiol Renal Physiol. 2009 Mar; 296(3):F477.
    View in: PubMed
    Score: 0.023
  24. Matrix metalloproteinase 13 (MMP13) and tissue inhibitor of matrix metalloproteinase 1 (TIMP1), regulated by the MAPK pathway, are both necessary for Madin-Darby canine kidney tubulogenesis. J Biol Chem. 2008 Feb 15; 283(7):4272-82.
    View in: PubMed
    Score: 0.022
  25. Branching out. Am J Physiol Renal Physiol. 2007 Oct; 293(4):F985-6.
    View in: PubMed
    Score: 0.021
  26. Intracellular signaling via ERK/MAPK completes the pathway for tubulogenic fibronectin in MDCK cells. Biochem Biophys Res Commun. 2007 Feb 16; 353(3):793-8.
    View in: PubMed
    Score: 0.020
  27. Activated extracellular signal-regulated kinases are necessary and sufficient to initiate tubulogenesis in renal tubular MDCK strain I cell cysts. Am J Physiol Renal Physiol. 2005 Oct; 289(4):F777-85.
    View in: PubMed
    Score: 0.018
  28. Extracellular signal-regulated kinases 1/2 control claudin-2 expression in Madin-Darby canine kidney strain I and II cells. J Biol Chem. 2005 Feb 04; 280(5):3780-8.
    View in: PubMed
    Score: 0.018
  29. The exocyst localizes to the primary cilium in MDCK cells. Biochem Biophys Res Commun. 2004 Jun 18; 319(1):138-43.
    View in: PubMed
    Score: 0.017
  30. Gene expression alterations during HGF-induced dedifferentiation of a renal tubular epithelial cell line (MDCK) using a novel canine DNA microarray. Am J Physiol Renal Physiol. 2004 Apr; 286(4):F702-10.
    View in: PubMed
    Score: 0.017
  31. The Rho family of small GTPases is involved in epithelial cystogenesis and tubulogenesis. Kidney Int. 2003 May; 63(5):1632-44.
    View in: PubMed
    Score: 0.016
  32. The exocyst affects protein synthesis by acting on the translocation machinery of the endoplasmic reticulum. J Biol Chem. 2003 Jun 06; 278(23):20954-60.
    View in: PubMed
    Score: 0.016
  33. Recent advances in the cell biology of polycystic kidney disease. Int Rev Cytol. 2003; 231:51-89.
    View in: PubMed
    Score: 0.015
  34. Exocytosis: the many masters of the exocyst. Curr Biol. 2002 Mar 19; 12(6):R212-4.
    View in: PubMed
    Score: 0.015
  35. Analysis of membrane traffic in polarized epithelial cells. Curr Protoc Cell Biol. 2001 Nov; Chapter 15:15.5.1-15.5.18.
    View in: PubMed
    Score: 0.014
  36. Phosphorylation of slit diaphragm proteins NEPHRIN and NEPH1 upon binding of HGF promotes podocyte repair. J Biol Chem. 2021 09; 297(3):101079.
    View in: PubMed
    Score: 0.014
  37. Targeting myosin 1c inhibits murine hepatic fibrogenesis. Am J Physiol Gastrointest Liver Physiol. 2021 06 01; 320(6):G1044-G1053.
    View in: PubMed
    Score: 0.014
  38. Exocyst is involved in cystogenesis and tubulogenesis and acts by modulating synthesis and delivery of basolateral plasma membrane and secretory proteins. Mol Biol Cell. 2000 Dec; 11(12):4259-75.
    View in: PubMed
    Score: 0.013
  39. A Functional Binding Domain in the Rbpr2 Receptor Is Required for Vitamin A Transport, Ocular Retinoid Homeostasis, and Photoreceptor Cell Survival in Zebrafish. Cells. 2020 04 29; 9(5).
    View in: PubMed
    Score: 0.013
  40. Desert hedgehog-primary cilia cross talk shapes mitral valve tissue by organizing smooth muscle actin. Dev Biol. 2020 07 01; 463(1):26-38.
    View in: PubMed
    Score: 0.013
  41. The Use of High-Throughput Transcriptomics to Identify Pathways with Therapeutic Significance in Podocytes. Int J Mol Sci. 2019 Dec 31; 21(1).
    View in: PubMed
    Score: 0.013
  42. Primary cilia defects causing mitral valve prolapse. Sci Transl Med. 2019 05 22; 11(493).
    View in: PubMed
    Score: 0.012
  43. The motor protein Myo1c regulates transforming growth factor-?-signaling and fibrosis in podocytes. Kidney Int. 2019 07; 96(1):139-158.
    View in: PubMed
    Score: 0.012
  44. Hepatocyte growth factor and the kidney: it is not just for the liver. Int Rev Cytol. 1999; 186:225-60.
    View in: PubMed
    Score: 0.012
  45. Clonality of urogenital organs as determined by analysis of chimeric mice. Cells Tissues Organs. 1999; 165(2):57-66.
    View in: PubMed
    Score: 0.012
  46. Molecular development of the kidney: a review of the results of gene disruption studies. Am J Kidney Dis. 1998 Mar; 31(3):383-97.
    View in: PubMed
    Score: 0.011
  47. Exocyst Complex Member EXOC5 Is Required for Survival of Hair Cells and Spiral Ganglion Neurons and Maintenance of Hearing. Mol Neurobiol. 2018 Aug; 55(8):6518-6532.
    View in: PubMed
    Score: 0.011
  48. Downregulation of exocyst Sec10 accelerates kidney tubule cell recovery through enhanced cell migration. Biochem Biophys Res Commun. 2018 02 05; 496(2):309-315.
    View in: PubMed
    Score: 0.011
  49. The Retinol-Binding Protein Receptor 2 (Rbpr2) Is Required for Photoreceptor Survival and Visual Function in the Zebrafish. Adv Exp Med Biol. 2018; 1074:569-576.
    View in: PubMed
    Score: 0.011
  50. Targeting Neph1 and ZO-1 protein-protein interaction in podocytes prevents podocyte injury and preserves glomerular filtration function. Sci Rep. 2017 09 21; 7(1):12047.
    View in: PubMed
    Score: 0.011
  51. A role for primary cilia in aortic valve development and disease. Dev Dyn. 2017 08; 246(8):625-634.
    View in: PubMed
    Score: 0.011
  52. Differentiation of rat neonatal ventral prostates grown in a serum-free organ culture system. Prostate. 1997 Jun 15; 32(1):35-42.
    View in: PubMed
    Score: 0.011
  53. Phenylacetate is an inhibitor of prostatic growth and development in organ culture. J Urol. 1996 May; 155(5):1762-70.
    View in: PubMed
    Score: 0.010
  54. Unilateral nephrectomy elongates primary cilia in the remaining kidney via reactive oxygen species. Sci Rep. 2016 Feb 29; 6:22281.
    View in: PubMed
    Score: 0.010
  55. Urothelial transformation into functional glandular tissue in situ by instructive mesenchymal induction. Kidney Int. 1996 Jan; 49(1):59-66.
    View in: PubMed
    Score: 0.010
  56. Arl13b and the exocyst interact synergistically in ciliogenesis. Mol Biol Cell. 2016 Jan 15; 27(2):308-20.
    View in: PubMed
    Score: 0.009
  57. A post-developmental genetic screen for zebrafish models of inherited liver disease. PLoS One. 2015; 10(5):e0125980.
    View in: PubMed
    Score: 0.009
  58. Activation of ERK accelerates repair of renal tubular epithelial cells, whereas it inhibits progression of fibrosis following ischemia/reperfusion injury. Biochim Biophys Acta. 2013 Dec; 1832(12):1998-2008.
    View in: PubMed
    Score: 0.008
  59. Reduction of oxidative stress during recovery accelerates normalization of primary cilia length that is altered after ischemic injury in murine kidneys. Am J Physiol Renal Physiol. 2013 May 15; 304(10):F1283-94.
    View in: PubMed
    Score: 0.008
  60. Simvastatin protection against acute immune-mediated glomerulonephritis in mice. Kidney Int. 2006 Feb; 69(3):457-63.
    View in: PubMed
    Score: 0.005
  61. ERK and MMPs sequentially regulate distinct stages of epithelial tubule development. Dev Cell. 2004 Jul; 7(1):21-32.
    View in: PubMed
    Score: 0.004
  62. Localization of GFP-tagged concentrative nucleoside transporters in a renal polarized epithelial cell line. Am J Physiol Renal Physiol. 2001 May; 280(5):F879-85.
    View in: PubMed
    Score: 0.003
  63. Keratinocyte growth factor (KGF) can replace testosterone in the ductal branching morphogenesis of the rat ventral prostate. Int J Dev Biol. 1996 Oct; 40(5):941-51.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.