Joshua Henry Lipschutz

TitleDirector, Division of Nephrology
InstitutionMedical University of South Carolina
DepartmentNephrology
AddressP.O. Box MSC 629
CSB 822-N
Clinical Science Bldg. - 96 Jonathan Lucas St.
Phone843-792-7659
Fax843-792-8399
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Han SJ, Kim JI, Lipschutz JH, Park KM, Han SJ, Kim JI, Lipschutz JH, Park KM. Hydrogen sulfide, a gaseous signaling molecule, elongates primary cilia on kidney tubular epithelial cells by activating extracellular signal-regulated kinase. Korean J Physiol Pharmacol. 2021 Nov 01; 25(6):593-601. PMID: 34697270; PMCID: PMC8552824.
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    2. Solanki AK, Arif E, Srivastava P, Furcht CM, Rahman B, Wen P, Singh A, Holzman LB, Fitzgibbon WR, Budisavljevic MN, Lobo GP, Kwon SH, Han Z, Lazzara MJ, Lipschutz JH, Nihalani D, Solanki AK, Arif E, Srivastava P, Furcht CM, Rahman B, Wen P, Singh A, Holzman LB, Fitzgibbon WR, Budisavljevic MN, Lobo GP, Kwon SH, Han Z, Lazzara MJ, Lipschutz JH, Nihalani D. Phosphorylation of slit diaphragm proteins NEPHRIN and NEPH1 upon binding of HGF promotes podocyte repair. J Biol Chem. 2021 09; 297(3):101079. PMID: 34391780; PMCID: PMC8429977.
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    3. Rohrer B, Biswal MR, Obert E, Dang Y, Su Y, Zuo X, Fogelgren B, Kondkar AA, Lobo GP, Lipschutz JH, Rohrer B, Biswal MR, Obert E, Dang Y, Su Y, Zuo X, Fogelgren B, Kondkar AA, Lobo GP, Lipschutz JH. Conditional Loss of the Exocyst Component Exoc5 in Retinal Pigment Epithelium (RPE) Results in RPE Dysfunction, Photoreceptor Cell Degeneration, and Decreased Visual Function. Int J Mol Sci. 2021 May 11; 22(10). PMID: 34064901; PMCID: PMC8151988.
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    4. Arif E, Wang C, Swiderska-Syn MK, Solanki AK, Rahman B, Manka PP, Coombes JD, Canbay A, Papa S, Nihalani D, Aspichueta P, Lipschutz JH, Syn WK, Arif E, Wang C, Swiderska-Syn MK, Solanki AK, Rahman B, Manka PP, Coombes JD, Canbay A, Papa S, Nihalani D, Aspichueta P, Lipschutz JH, Syn WK. Targeting myosin 1c inhibits murine hepatic fibrogenesis. Am J Physiol Gastrointest Liver Physiol. 2021 06 01; 320(6):G1044-G1053. PMID: 33908271; PMCID: PMC8285590.
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    5. Solanki AK, Kondkar AA, Fogerty J, Su Y, Kim SH, Lipschutz JH, Nihalani D, Perkins BD, Lobo GP, Solanki AK, Kondkar AA, Fogerty J, Su Y, Kim SH, Lipschutz JH, Nihalani D, Perkins BD, Lobo GP. A Functional Binding Domain in the Rbpr2 Receptor Is Required for Vitamin A Transport, Ocular Retinoid Homeostasis, and Photoreceptor Cell Survival in Zebrafish. Cells. 2020 04 29; 9(5). PMID: 32365517; PMCID: PMC7290320.
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    6. Fulmer D, Toomer KA, Glover J, Guo L, Moore K, Moore R, Stairley R, Gensemer C, Abrol S, Rumph MK, Emetu F, Lipschutz JH, McDowell C, Bian J, Wang C, Beck T, Wessels A, Renault MA, Norris RA, Fulmer D, Toomer KA, Glover J, Guo L, Moore K, Moore R, Stairley R, Gensemer C, Abrol S, Rumph MK, Emetu F, Lipschutz JH, McDowell C, Bian J, Wang C, Beck T, Wessels A, Renault MA, Norris RA. Desert hedgehog-primary cilia cross talk shapes mitral valve tissue by organizing smooth muscle actin. Dev Biol. 2020 07 01; 463(1):26-38. PMID: 32151560; PMCID: PMC7281834.
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    7. Solanki AK, Srivastava P, Rahman B, Lipschutz JH, Nihalani D, Arif E, Solanki AK, Srivastava P, Rahman B, Lipschutz JH, Nihalani D, Arif E. The Use of High-Throughput Transcriptomics to Identify Pathways with Therapeutic Significance in Podocytes. Int J Mol Sci. 2019 Dec 31; 21(1). PMID: 31906131; PMCID: PMC6981397.
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    8. Zuo X, Kwon SH, Janech MG, Dang Y, Lauzon SD, Fogelgren B, Polgar N, Lipschutz JH, Zuo X, Kwon SH, Janech MG, Dang Y, Lauzon SD, Fogelgren B, Polgar N, Lipschutz JH. Primary cilia and the exocyst are linked to urinary extracellular vesicle production and content. J Biol Chem. 2019 12 13; 294(50):19099-19110. PMID: 31694916; PMCID: PMC6916495.
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    9. Lipschutz JH, Lipschutz JH. The role of the exocyst in renal ciliogenesis, cystogenesis, tubulogenesis, and development. Kidney Res Clin Pract. 2019 Sep 30; 38(3):260-266. PMID: 31284362; PMCID: PMC6727897.
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    10. Fulmer D, Toomer K, Guo L, Moore K, Glover J, Moore R, Stairley R, Lobo G, Zuo X, Dang Y, Su Y, Fogelgren B, Gerard P, Chung D, Heydarpour M, Mukherjee R, Body SC, Norris RA, Lipschutz JH, Fulmer D, Toomer K, Guo L, Moore K, Glover J, Moore R, Stairley R, Lobo G, Zuo X, Dang Y, Su Y, Fogelgren B, Gerard P, Chung D, Heydarpour M, Mukherjee R, Body SC, Norris RA, Lipschutz JH. Defects in the Exocyst-Cilia Machinery Cause Bicuspid Aortic Valve Disease and Aortic Stenosis. Circulation. 2019 10 15; 140(16):1331-1341. PMID: 31387361; PMCID: PMC6989054.
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    11. Toomer KA, Yu M, Fulmer D, Guo L, Moore KS, Moore R, Drayton KD, Glover J, Peterson N, Ramos-Ortiz S, Drohan A, Catching BJ, Stairley R, Wessels A, Lipschutz JH, Delling FN, Jeunemaitre X, Dina C, Collins RL, Brand H, Talkowski ME, Del Monte F, Mukherjee R, Awgulewitsch A, Body S, Hardiman G, Hazard ES, da Silveira WA, Wang B, Leyne M, Durst R, Markwald RR, Le Scouarnec S, Hagege A, Le Tourneau T, Kohl P, Rog-Zielinska EA, Ellinor PT, Levine RA, Milan DJ, Schott JJ, Bouatia-Naji N, Slaugenhaupt SA, Norris RA, Toomer KA, Yu M, Fulmer D, Guo L, Moore KS, Moore R, Drayton KD, Glover J, Peterson N, Ramos-Ortiz S, Drohan A, Catching BJ, Stairley R, Wessels A, Lipschutz JH, Delling FN, Jeunemaitre X, Dina C, Collins RL, Brand H, Talkowski ME, Del Monte F, Mukherjee R, Awgulewitsch A, Body S, Hardiman G, Hazard ES, da Silveira WA, Wang B, Leyne M, Durst R, Markwald RR, Le Scouarnec S, Hagege A, Le Tourneau T, Kohl P, Rog-Zielinska EA, Ellinor PT, Levine RA, Milan DJ, Schott JJ, Bouatia-Naji N, Slaugenhaupt SA, Norris RA. Primary cilia defects causing mitral valve prolapse. Sci Transl Med. 2019 05 22; 11(493). PMID: 31118289; PMCID: PMC7331025.
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    12. Nihalani D, Solanki AK, Arif E, Srivastava P, Rahman B, Zuo X, Dang Y, Fogelgren B, Fermin D, Gillies CE, Sampson MG, Lipschutz JH, Nihalani D, Solanki AK, Arif E, Srivastava P, Rahman B, Zuo X, Dang Y, Fogelgren B, Fermin D, Gillies CE, Sampson MG, Lipschutz JH. Disruption of the exocyst induces podocyte loss and dysfunction. J Biol Chem. 2019 06 28; 294(26):10104-10119. PMID: 31073028; PMCID: PMC6664173.
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    13. Arif E, Solanki AK, Srivastava P, Rahman B, Tash BR, Holzman LB, Janech MG, Martin R, Knölker HJ, Fitzgibbon WR, Deng P, Budisavljevic MN, Syn WK, Wang C, Lipschutz JH, Kwon SH, Nihalani D, Arif E, Solanki AK, Srivastava P, Rahman B, Tash BR, Holzman LB, Janech MG, Martin R, Kn?lker HJ, Fitzgibbon WR, Deng P, Budisavljevic MN, Syn WK, Wang C, Lipschutz JH, Kwon SH, Nihalani D. The motor protein Myo1c regulates transforming growth factor-?-signaling and fibrosis in podocytes. Kidney Int. 2019 07; 96(1):139-158. PMID: 31097328; PMCID: PMC6589397.
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    14. Zuo X, Lobo G, Fulmer D, Guo L, Dang Y, Su Y, Ilatovskaya DV, Nihalani D, Rohrer B, Body SC, Norris RA, Lipschutz JH, Zuo X, Lobo G, Fulmer D, Guo L, Dang Y, Su Y, Ilatovskaya DV, Nihalani D, Rohrer B, Body SC, Norris RA, Lipschutz JH. The exocyst acting through the primary cilium is necessary for renal ciliogenesis, cystogenesis, and tubulogenesis. J Biol Chem. 2019 04 26; 294(17):6710-6718. PMID: 30824539; PMCID: PMC6497951.
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    15. Lee B, Baek JI, Min H, Bae SH, Moon K, Kim MA, Kim YR, Fogelgren B, Lipschutz JH, Lee KY, Bok J, Kim UK, Lee B, Baek JI, Min H, Bae SH, Moon K, Kim MA, Kim YR, Fogelgren B, Lipschutz JH, Lee KY, Bok J, Kim UK. Correction to: Exocyst Complex Member EXOC5 Is Required for Survival of Hair Cells and Spiral Ganglion Neurons and Maintenance of Hearing. Mol Neurobiol. 2019 Mar; 56(3):2300. PMID: 30637586.
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    16. Lee B, Baek JI, Min H, Bae SH, Moon K, Kim MA, Kim YR, Fogelgren B, Lipschutz JH, Lee KY, Bok J, Kim UK, Lee B, Baek JI, Min H, Bae SH, Moon K, Kim MA, Kim YR, Fogelgren B, Lipschutz JH, Lee KY, Bok J, Kim UK. Exocyst Complex Member EXOC5 Is Required for Survival of Hair Cells and Spiral Ganglion Neurons and Maintenance of Hearing. Mol Neurobiol. 2018 Aug; 55(8):6518-6532. PMID: 29327200; PMCID: PMC6984595.
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    17. Noh MR, Jang HS, Song DK, Lee SR, Lipschutz JH, Park KM, Kim JI, Noh MR, Jang HS, Song DK, Lee SR, Lipschutz JH, Park KM, Kim JI. Downregulation of exocyst Sec10 accelerates kidney tubule cell recovery through enhanced cell migration. Biochem Biophys Res Commun. 2018 02 05; 496(2):309-315. PMID: 29326040.
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    18. Lobo GP, Pauer G, Lipschutz JH, Hagstrom SA, Lobo GP, Pauer G, Lipschutz JH, Hagstrom SA. The Retinol-Binding Protein Receptor 2 (Rbpr2) Is Required for Photoreceptor Survival and Visual Function in the Zebrafish. Adv Exp Med Biol. 2018; 1074:569-576. PMID: 29721989.
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    19. Shi Y, Su Y, Lipschutz JH, Lobo GP, Shi Y, Su Y, Lipschutz JH, Lobo GP. Zebrafish as models to study ciliopathies of the eye and kidney. Clin Nephrol Res. 2017 Dec; 1(1):6-9. PMID: 29553143; PMCID: PMC5851006.
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    20. Kwon SH, Oh S, Nacke M, Mostov KE, Lipschutz JH, Kwon SH, Oh S, Nacke M, Mostov KE, Lipschutz JH. Adaptor protein CD2AP and L-type lectin LMAN2 regulate exosome cargo protein trafficking through the Golgi complex. J Biol Chem. 2017 10 06; 292(40):16523. PMID: 28986432; PMCID: PMC5633114.
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    21. Sagar A, Arif E, Solanki AK, Srivastava P, Janech MG, Kim SH, Lipschutz JH, Kwon SH, Nihalani D, Sagar A, Arif E, Solanki AK, Srivastava P, Janech MG, Kim SH, Lipschutz JH, Kwon SH, Nihalani D. Targeting Neph1 and ZO-1 protein-protein interaction in podocytes prevents podocyte injury and preserves glomerular filtration function. Sci Rep. 2017 09 21; 7(1):12047. PMID: 28935902; PMCID: PMC5608913.
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    22. Lobo GP, Fulmer D, Guo L, Zuo X, Dang Y, Kim SH, Su Y, George K, Obert E, Fogelgren B, Nihalani D, Norris RA, Rohrer B, Lipschutz JH, Lobo GP, Fulmer D, Guo L, Zuo X, Dang Y, Kim SH, Su Y, George K, Obert E, Fogelgren B, Nihalani D, Norris RA, Rohrer B, Lipschutz JH. The exocyst is required for photoreceptor ciliogenesis and retinal development. J Biol Chem. 2017 09 08; 292(36):14814-14826. PMID: 28729419; PMCID: PMC5592663.
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    23. Toomer KA, Fulmer D, Guo L, Drohan A, Peterson N, Swanson P, Brooks B, Mukherjee R, Body S, Lipschutz JH, Wessels A, Norris RA, Toomer KA, Fulmer D, Guo L, Drohan A, Peterson N, Swanson P, Brooks B, Mukherjee R, Body S, Lipschutz JH, Wessels A, Norris RA. A role for primary cilia in aortic valve development and disease. Dev Dyn. 2017 08; 246(8):625-634. PMID: 28556366; PMCID: PMC5548133.
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    24. Kwon SH, Oh S, Nacke M, Mostov KE, Lipschutz JH, Kwon SH, Oh S, Nacke M, Mostov KE, Lipschutz JH. Adaptor Protein CD2AP and L-type Lectin LMAN2 Regulate Exosome Cargo Protein Trafficking through the Golgi Complex. J Biol Chem. 2016 Dec 02; 291(49):25462-25475. PMID: 27765817; PMCID: PMC5207247.
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    25. Han SJ, Jang HS, Kim JI, Lipschutz JH, Park KM, Han SJ, Jang HS, Kim JI, Lipschutz JH, Park KM. Unilateral nephrectomy elongates primary cilia in the remaining kidney via reactive oxygen species. Sci Rep. 2016 Feb 29; 6:22281. PMID: 26923764; PMCID: PMC4770282.
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    26. Baek JI, Kwon SH, Zuo X, Choi SY, Kim SH, Lipschutz JH, Baek JI, Kwon SH, Zuo X, Choi SY, Kim SH, Lipschutz JH. Dynamin Binding Protein (Tuba) Deficiency Inhibits Ciliogenesis and Nephrogenesis in Vitro and in Vivo. J Biol Chem. 2016 Apr 15; 291(16):8632-43. PMID: 26895965; PMCID: PMC4861433.
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    27. Seixas C, Choi SY, Polgar N, Umberger NL, East MP, Zuo X, Moreiras H, Ghossoub R, Benmerah A, Kahn RA, Fogelgren B, Caspary T, Lipschutz JH, Barral DC, Seixas C, Choi SY, Polgar N, Umberger NL, East MP, Zuo X, Moreiras H, Ghossoub R, Benmerah A, Kahn RA, Fogelgren B, Caspary T, Lipschutz JH, Barral DC. Arl13b and the exocyst interact synergistically in ciliogenesis. Mol Biol Cell. 2016 Jan 15; 27(2):308-20. PMID: 26582389; PMCID: PMC4713133.
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    28. Fogelgren B, Polgar N, Lui VH, Lee AJ, Tamashiro KK, Napoli JA, Walton CB, Zuo X, Lipschutz JH, Fogelgren B, Polgar N, Lui VH, Lee AJ, Tamashiro KK, Napoli JA, Walton CB, Zuo X, Lipschutz JH. Urothelial Defects from Targeted Inactivation of Exocyst Sec10 in Mice Cause Ureteropelvic Junction Obstructions. PLoS One. 2015; 10(6):e0129346. PMID: 26046524; PMCID: PMC4457632.
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    29. Kim SH, Wu SY, Baek JI, Choi SY, Su Y, Flynn CR, Gamse JT, Ess KC, Hardiman G, Lipschutz JH, Abumrad NN, Rockey DC, Kim SH, Wu SY, Baek JI, Choi SY, Su Y, Flynn CR, Gamse JT, Ess KC, Hardiman G, Lipschutz JH, Abumrad NN, Rockey DC. A post-developmental genetic screen for zebrafish models of inherited liver disease. PLoS One. 2015; 10(5):e0125980. PMID: 25950913; PMCID: PMC4423964.
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    30. Alam A, Dahl NK, Lipschutz JH, Rossetti S, Smith P, Sapir D, Weinstein J, McFarlane P, Bichet DG, Alam A, Dahl NK, Lipschutz JH, Rossetti S, Smith P, Sapir D, Weinstein J, McFarlane P, Bichet DG. Total Kidney Volume in Autosomal Dominant Polycystic Kidney Disease: A Biomarker of Disease Progression and Therapeutic Efficacy. Am J Kidney Dis. 2015 Oct; 66(4):564-76. PMID: 25960302.
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    31. Choi SY, Baek JI, Zuo X, Kim SH, Dunaief JL, Lipschutz JH, Choi SY, Baek JI, Zuo X, Kim SH, Dunaief JL, Lipschutz JH. Cdc42 and sec10 Are Required for Normal Retinal Development in Zebrafish. Invest Ophthalmol Vis Sci. 2015 May; 56(5):3361-70. PMID: 26024121; PMCID: PMC4453986.
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    32. Huang L, Xiao A, Wecker A, McBride DA, Choi SY, Zhou W, Lipschutz JH, Huang L, Xiao A, Wecker A, McBride DA, Choi SY, Zhou W, Lipschutz JH. A possible zebrafish model of polycystic kidney disease: knockdown of wnt5a causes cysts in zebrafish kidneys. J Vis Exp. 2014 Dec 02; (94). PMID: 25489842; PMCID: PMC4354438.
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    33. Huang L, Xiao A, Choi SY, Kan Q, Zhou W, Chacon-Heszele MF, Ryu YK, McKenna S, Zuo X, Kuruvilla R, Lipschutz JH, Huang L, Xiao A, Choi SY, Kan Q, Zhou W, Chacon-Heszele MF, Ryu YK, McKenna S, Zuo X, Kuruvilla R, Lipschutz JH. Wnt5a is necessary for normal kidney development in zebrafish and mice. Nephron Exp Nephrol. 2014; 128(1-2):80-8. PMID: 25412793; PMCID: PMC4382204.
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    34. Fogelgren B, Zuo X, Buonato JM, Vasilyev A, Baek JI, Choi SY, Chacon-Heszele MF, Palmyre A, Polgar N, Drummond I, Park KM, Lazzara MJ, Lipschutz JH, Fogelgren B, Zuo X, Buonato JM, Vasilyev A, Baek JI, Choi SY, Chacon-Heszele MF, Palmyre A, Polgar N, Drummond I, Park KM, Lazzara MJ, Lipschutz JH. Exocyst Sec10 protects renal tubule cells from injury by EGFR/MAPK activation and effects on endocytosis. Am J Physiol Renal Physiol. 2014 Dec 15; 307(12):F1334-41. PMID: 25298525; PMCID: PMC4269694.
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    35. Chacon-Heszele MF, Choi SY, Zuo X, Baek JI, Ward C, Lipschutz JH, Chacon-Heszele MF, Choi SY, Zuo X, Baek JI, Ward C, Lipschutz JH. The exocyst and regulatory GTPases in urinary exosomes. Physiol Rep. 2014 Aug 01; 2(8). PMID: 25138791; PMCID: PMC4246586.
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    36. Huang L, Lipschutz JH, Huang L, Lipschutz JH. Cilia and polycystic kidney disease, kith and kin. Birth Defects Res C Embryo Today. 2014 Jun; 102(2):174-85. PMID: 24898006; PMCID: PMC4374053.
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    37. Chacon-Heszele MF, Zuo X, Hellman NE, McKenna S, Choi SY, Huang L, Tobias JW, Park KM, Lipschutz JH, Chacon-Heszele MF, Zuo X, Hellman NE, McKenna S, Choi SY, Huang L, Tobias JW, Park KM, Lipschutz JH. Novel MAPK-dependent and -independent tubulogenes identified via microarray analysis of 3D-cultured Madin-Darby canine kidney cells. Am J Physiol Renal Physiol. 2014 May 01; 306(9):F1047-58. PMID: 24573390; PMCID: PMC4010684.
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    38. Baek JI, Choi SY, Chacon-Heszele MF, Zuo X, Lipschutz JH, Baek JI, Choi SY, Chacon-Heszele MF, Zuo X, Lipschutz JH. Expression of Drosophila forkhead transcription factors during kidney development. Biochem Biophys Res Commun. 2014 Mar 28; 446(1):15-7. PMID: 24491558; PMCID: PMC4016985.
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    39. Jang HS, Han SJ, Kim JI, Lee S, Lipschutz JH, Park KM, Jang HS, Han SJ, Kim JI, Lee S, Lipschutz JH, Park KM. Activation of ERK accelerates repair of renal tubular epithelial cells, whereas it inhibits progression of fibrosis following ischemia/reperfusion injury. Biochim Biophys Acta. 2013 Dec; 1832(12):1998-2008. PMID: 23851027.
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    40. Choi SY, Chacon-Heszele MF, Huang L, McKenna S, Wilson FP, Zuo X, Lipschutz JH, Choi SY, Chacon-Heszele MF, Huang L, McKenna S, Wilson FP, Zuo X, Lipschutz JH. Cdc42 deficiency causes ciliary abnormalities and cystic kidneys. J Am Soc Nephrol. 2013 Sep; 24(9):1435-50. PMID: 23766535; PMCID: PMC3752951.
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    41. Orr RK, Hoehn JL, Col NF, Kim JI, Kim J, Jang HS, Noh MR, Lipschutz JH, Park KM. Reduction of oxidative stress during recovery accelerates normalization of primary cilia length that is altered after ischemic injury in murine kidneys. Am J Physiol Renal Physiol. 2013 May 15; 304(10):F1283-94. PMID: 23515720.
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    42. Choi SY, Fogelgren B, Zuo X, Huang L, McKenna S, Lingappa VR, Lipschutz JH, Choi SY, Fogelgren B, Zuo X, Huang L, McKenna S, Lingappa VR, Lipschutz JH. Exocyst Sec10 is involved in basolateral protein translation and translocation in the endoplasmic reticulum. Nephron Exp Nephrol. 2012; 120(4):e134-40. PMID: 23037926; PMCID: PMC3740206.
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    43. Chung DC, Fogelgren B, Park KM, Heidenberg J, Zuo X, Huang L, Bennett J, Lipschutz JH, Chung DC, Fogelgren B, Park KM, Heidenberg J, Zuo X, Huang L, Bennett J, Lipschutz JH. Adeno-Associated Virus-Mediated Gene Transfer to Renal Tubule Cells via a Retrograde Ureteral Approach. Nephron Extra. 2011 Jan; 1(1):217-23. PMID: 22470395; PMCID: PMC3290852.
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    44. Zuo X, Fogelgren B, Lipschutz JH, Zuo X, Fogelgren B, Lipschutz JH. The small GTPase Cdc42 is necessary for primary ciliogenesis in renal tubular epithelial cells. J Biol Chem. 2011 Jun 24; 286(25):22469-77. PMID: 21543338; PMCID: PMC3121392.
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    45. Fogelgren B, Lin SY, Zuo X, Jaffe KM, Park KM, Reichert RJ, Bell PD, Burdine RD, Lipschutz JH, Fogelgren B, Lin SY, Zuo X, Jaffe KM, Park KM, Reichert RJ, Bell PD, Burdine RD, Lipschutz JH. The exocyst protein Sec10 interacts with Polycystin-2 and knockdown causes PKD-phenotypes. PLoS Genet. 2011 Apr; 7(4):e1001361. PMID: 21490950; PMCID: PMC3072367.
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    46. Blosser CD, Ayehu G, Wu S, Lomagro RM, Malone E, Brunelli SM, Itkin M, Golden M, McCombs P, Lipschutz JH, Blosser CD, Ayehu G, Wu S, Lomagro RM, Malone E, Brunelli SM, Itkin M, Golden M, McCombs P, Lipschutz JH. High rate of fistula placement in a cohort of dialysis patients in a single payer system. Hemodial Int. 2010 Oct; 14(4):393-7. PMID: 20812959; PMCID: PMC3082920.
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    47. Park KM, Fogelgren B, Zuo X, Kim J, Chung DC, Lipschutz JH, Park KM, Fogelgren B, Zuo X, Kim J, Chung DC, Lipschutz JH. Exocyst Sec10 protects epithelial barrier integrity and enhances recovery following oxidative stress, by activation of the MAPK pathway. Am J Physiol Renal Physiol. 2010 Mar; 298(3):F818-26. PMID: 20053792; PMCID: PMC2838587.
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    48. Lipschutz JH, Lipschutz JH. Electronic health records in hospitals. N Engl J Med. 2009 Jul 23; 361(4):421; author reply 422. PMID: 19625724.
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    49. Zuo X, Guo W, Lipschutz JH, Zuo X, Guo W, Lipschutz JH. The exocyst protein Sec10 is necessary for primary ciliogenesis and cystogenesis in vitro. Mol Biol Cell. 2009 May; 20(10):2522-9. PMID: 19297529; PMCID: PMC2682593.
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    50. Lipschutz JH, Lipschutz JH. Tubule and cyst formation: lightning strikes twice. Am J Physiol Renal Physiol. 2009 Mar; 296(3):F477. PMID: 19129261.
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    51. Berman E, Lipschutz JM, Bloom RD, Lipschutz JH, Berman E, Lipschutz JM, Bloom RD, Lipschutz JH. The bioethics and utility of selling kidneys for renal transplantation. Transplant Proc. 2008 Jun; 40(5):1264-70. PMID: 18589084; PMCID: PMC2504358.
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    52. Hellman NE, Spector J, Robinson J, Zuo X, Saunier S, Antignac C, Tobias JW, Lipschutz JH, Hellman NE, Spector J, Robinson J, Zuo X, Saunier S, Antignac C, Tobias JW, Lipschutz JH. Matrix metalloproteinase 13 (MMP13) and tissue inhibitor of matrix metalloproteinase 1 (TIMP1), regulated by the MAPK pathway, are both necessary for Madin-Darby canine kidney tubulogenesis. J Biol Chem. 2008 Feb 15; 283(7):4272-82. PMID: 18039671.
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    53. Lipschutz JH, Lipschutz JH. Branching out. Am J Physiol Renal Physiol. 2007 Oct; 293(4):F985-6. PMID: 17652369.
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    54. Orr RK, Hoehn JL, Col NF, Huber WG, Dahman MH, Thomas D, Lipschutz JH. Practical advance in obtaining an emergency airway via cricothyroidotomy. Mil Med. 2007 May; 172(5):504-6. PMID: 17521098.
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    55. Orr RK, Hoehn JL, Col NF, Liu Z, Greco AJ, Hellman NE, Spector J, Robinson J, Tang OT, Lipschutz JH. Intracellular signaling via ERK/MAPK completes the pathway for tubulogenic fibronectin in MDCK cells. Biochem Biophys Res Commun. 2007 Feb 16; 353(3):793-8. PMID: 17196167; PMCID: PMC1839983.
      Citations:    
    56. Christensen M, Su AW, Snyder RW, Greco A, Lipschutz JH, Madaio MP, Christensen M, Su AW, Snyder RW, Greco A, Lipschutz JH, Madaio MP. Simvastatin protection against acute immune-mediated glomerulonephritis in mice. Kidney Int. 2006 Feb; 69(3):457-63. PMID: 16407885.
      Citations:    
    57. Hellman NE, Greco AJ, Rogers KK, Kanchagar C, Balkovetz DF, Lipschutz JH, Hellman NE, Greco AJ, Rogers KK, Kanchagar C, Balkovetz DF, Lipschutz JH. Activated extracellular signal-regulated kinases are necessary and sufficient to initiate tubulogenesis in renal tubular MDCK strain I cell cysts. Am J Physiol Renal Physiol. 2005 Oct; 289(4):F777-85. PMID: 15900019.
      Citations:    
    58. Lipschutz JH, Li S, Arisco A, Balkovetz DF, Lipschutz JH, Li S, Arisco A, Balkovetz DF. Extracellular signal-regulated kinases 1/2 control claudin-2 expression in Madin-Darby canine kidney strain I and II cells. J Biol Chem. 2005 Feb 04; 280(5):3780-8. PMID: 15569684.
      Citations:    
    59. Berman E, Merz JF, Rudnick M, Snyder RW, Rogers KK, Lee J, Johnson D, Mosenkis A, Israni A, Wolpe PR, Lipschutz JH, Berman E, Merz JF, Rudnick M, Snyder RW, Rogers KK, Lee J, Johnson D, Mosenkis A, Israni A, Wolpe PR, Lipschutz JH. Religiosity in a hemodialysis population and its relationship to satisfaction with medical care, satisfaction with life, and adherence. Am J Kidney Dis. 2004 Sep; 44(3):488-97. PMID: 15332222.
      Citations:    
    60. Snyder RW, Ruhe J, Kobrin S, Wasserstein A, Doline C, Nachamkin I, Lipschutz JH, Snyder RW, Ruhe J, Kobrin S, Wasserstein A, Doline C, Nachamkin I, Lipschutz JH. Asaia bogorensis peritonitis identified by 16S ribosomal RNA sequence analysis in a patient receiving peritoneal dialysis. Am J Kidney Dis. 2004 Aug; 44(2):e15-7. PMID: 15264206.
      Citations:    
    61. O'Brien LE, Tang K, Kats ES, Schutz-Geschwender A, Lipschutz JH, Mostov KE, O'Brien LE, Tang K, Kats ES, Schutz-Geschwender A, Lipschutz JH, Mostov KE. ERK and MMPs sequentially regulate distinct stages of epithelial tubule development. Dev Cell. 2004 Jul; 7(1):21-32. PMID: 15239951.
      Citations:    
    62. Rogers KK, Wilson PD, Snyder RW, Zhang X, Guo W, Burrow CR, Lipschutz JH, Rogers KK, Wilson PD, Snyder RW, Zhang X, Guo W, Burrow CR, Lipschutz JH. The exocyst localizes to the primary cilium in MDCK cells. Biochem Biophys Res Commun. 2004 Jun 18; 319(1):138-43. PMID: 15158452.
      Citations:    
    63. Orr RK, Hoehn JL, Col NF, Balkovetz DF, Gerrard ER, Li S, Johnson D, Lee J, Tobias JW, Rogers KK, Snyder RW, Lipschutz JH. Gene expression alterations during HGF-induced dedifferentiation of a renal tubular epithelial cell line (MDCK) using a novel canine DNA microarray. Am J Physiol Renal Physiol. 2004 Apr; 286(4):F702-10. PMID: 14665430.
      Citations: 13     Fields:    Translation:AnimalsCells
    64. Rogers KK, Jou TS, Guo W, Lipschutz JH, Rogers KK, Jou TS, Guo W, Lipschutz JH. The Rho family of small GTPases is involved in epithelial cystogenesis and tubulogenesis. Kidney Int. 2003 May; 63(5):1632-44. PMID: 12675838.
      Citations: 32     Fields:    Translation:AnimalsCells
    65. Lipschutz JH, Lingappa VR, Mostov KE, Lipschutz JH, Lingappa VR, Mostov KE. The exocyst affects protein synthesis by acting on the translocation machinery of the endoplasmic reticulum. J Biol Chem. 2003 Jun 06; 278(23):20954-60. PMID: 12665531.
      Citations: 47     Fields:    Translation:AnimalsCells
    66. Smyth BJ, Snyder RW, Balkovetz DF, Lipschutz JH, Smyth BJ, Snyder RW, Balkovetz DF, Lipschutz JH. Recent advances in the cell biology of polycystic kidney disease. Int Rev Cytol. 2003; 231:51-89. PMID: 14713003.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    67. Lipschutz JH, Mostov KE, Lipschutz JH, Mostov KE. Exocytosis: the many masters of the exocyst. Curr Biol. 2002 Mar 19; 12(6):R212-4. PMID: 11909549.
      Citations: 86     Fields:    Translation:HumansAnimals
    68. Lipschutz JH, O'Brien LE, Altschuler Y, Avrahami D, Nguyen Y, Tang K, Mostov KE, Lipschutz JH, O'Brien LE, Altschuler Y, Avrahami D, Nguyen Y, Tang K, Mostov KE. Analysis of membrane traffic in polarized epithelial cells. Curr Protoc Cell Biol. 2001 Nov; Chapter 15:15.5.1-15.5.18. PMID: 18228332.
      Citations:    
    69. Orr RK, Hoehn JL, Col NF, Mangravite LM, Lipschutz JH, Mostov KE, Giacomini KM. Localization of GFP-tagged concentrative nucleoside transporters in a renal polarized epithelial cell line. Am J Physiol Renal Physiol. 2001 May; 280(5):F879-85. PMID: 11292631.
      Citations: 10     Fields:    Translation:AnimalsCells
    70. Lipschutz JH, Guo W, O'Brien LE, Nguyen YH, Novick P, Mostov KE, Lipschutz JH, Guo W, O'Brien LE, Nguyen YH, Novick P, Mostov KE. Exocyst is involved in cystogenesis and tubulogenesis and acts by modulating synthesis and delivery of basolateral plasma membrane and secretory proteins. Mol Biol Cell. 2000 Dec; 11(12):4259-75. PMID: 11102522; PMCID: PMC15071.
      Citations: 58     Fields:    Translation:AnimalsCells
    71. Lipschutz JH, Lipschutz JH. To clone or not to clone--a Jewish perspective. J Med Ethics. 1999 Apr; 25(2):105-7. PMID: 10226913; PMCID: PMC479191.
      Citations:    Fields:    Translation:Humans
    72. Lipschutz JH, Fukami H, Yamamoto M, Tatematsu M, Sugimura Y, Kusakabe M, Cunha G, Lipschutz JH, Fukami H, Yamamoto M, Tatematsu M, Sugimura Y, Kusakabe M, Cunha G. Clonality of urogenital organs as determined by analysis of chimeric mice. Cells Tissues Organs. 1999; 165(2):57-66. PMID: 10516418.
      Citations: 2     Fields:    Translation:Animals
    73. Balkovetz DF, Lipschutz JH, Balkovetz DF, Lipschutz JH. Hepatocyte growth factor and the kidney: it is not just for the liver. Int Rev Cytol. 1999; 186:225-60. PMID: 9770301.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    74. Lipschutz JH, Kissil JL, Lipschutz JH, Kissil JL. Expression of beta-catenin and gamma-catenin in epithelial tumor cell lines and characterization of a unique cell line. Cancer Lett. 1998 Apr 10; 126(1):33-41. PMID: 9563646.
      Citations: 2     Fields:    Translation:HumansCells
    75. Lipschutz JH, Lipschutz JH. Molecular development of the kidney: a review of the results of gene disruption studies. Am J Kidney Dis. 1998 Mar; 31(3):383-97. PMID: 9506676.
      Citations: 25     Fields:    Translation:HumansAnimals
    76. Baskin LS, Sutherland RS, DiSandro MJ, Hayward SW, Lipschutz J, Cunha GR, Baskin LS, Sutherland RS, DiSandro MJ, Hayward SW, Lipschutz J, Cunha GR. The effect of testosterone on androgen receptors and human penile growth. J Urol. 1997 Sep; 158(3 Pt 2):1113-8. PMID: 9258152.
      Citations: 16     Fields:    Translation:Humans
    77. Lipschutz JH, Foster BA, Cunha GR, Lipschutz JH, Foster BA, Cunha GR. Differentiation of rat neonatal ventral prostates grown in a serum-free organ culture system. Prostate. 1997 Jun 15; 32(1):35-42. PMID: 9207955.
      Citations: 10     Fields:    Translation:Animals
    78. Sugimura Y, Foster BA, Hom YK, Lipschutz JH, Rubin JS, Finch PW, Aaronson SA, Hayashi N, Kawamura J, Cunha GR, Sugimura Y, Foster BA, Hom YK, Lipschutz JH, Rubin JS, Finch PW, Aaronson SA, Hayashi N, Kawamura J, Cunha GR. Keratinocyte growth factor (KGF) can replace testosterone in the ductal branching morphogenesis of the rat ventral prostate. Int J Dev Biol. 1996 Oct; 40(5):941-51. PMID: 8946242.
      Citations: 27     Fields:    Translation:AnimalsCells
    79. Lipschutz JH, Samid D, Cunha GR, Lipschutz JH, Samid D, Cunha GR. Phenylacetate is an inhibitor of prostatic growth and development in organ culture. J Urol. 1996 May; 155(5):1762-70. PMID: 8627880.
      Citations: 2     Fields:    Translation:Animals
    80. Lipschutz JH, Young P, Taguchi O, Cunha GR, Lipschutz JH, Young P, Taguchi O, Cunha GR. Urothelial transformation into functional glandular tissue in situ by instructive mesenchymal induction. Kidney Int. 1996 Jan; 49(1):59-66. PMID: 8770949.
      Citations: 5     Fields:    Translation:AnimalsCells
    81. Lipschutz JH, Miller T, Yen TS, Vartanian RK, Graber ML, Damon L, Lipschutz JH, Miller T, Yen TS, Vartanian RK, Graber ML, Damon L. Unreliability of the abdominal fat pad biopsy in the evaluation of nephrosis: report of 3 consecutive cases. Am J Nephrol. 1995; 15(5):431-5. PMID: 7503144.
      Citations:    Fields:    Translation:Humans
    82. Lipschutz JH, Arieff AI, Lipschutz JH, Arieff AI. Reset osmostat in a healthy patient. Ann Intern Med. 1994 Apr 01; 120(7):574-6. PMID: 8116995.
      Citations: 1     Fields:    Translation:Humans
    83. Lipschutz JH, Canal DF, Hawes RH, Ruffolo TA, Besold MA, Lehman GA, Lipschutz JH, Canal DF, Hawes RH, Ruffolo TA, Besold MA, Lehman GA. Laparoscopic cholecystectomy and ERCP with sphincterotomy in an elderly patient with situs inversus. Am J Gastroenterol. 1992 Feb; 87(2):218-20. PMID: 1531164.
      Citations: 9     Fields:    Translation:Humans
    84. Lipschutz JH, Pascuzzi RM, Bognanno J, Putty T, Lipschutz JH, Pascuzzi RM, Bognanno J, Putty T. Bilateral anterior cerebral artery infarction resulting from explosion-type injury to the head and neck. Stroke. 1991 Jun; 22(6):813-5. PMID: 2057983.
      Citations:    Fields:    Translation:Humans
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