Gustavo Leone to Mice, Knockout
This is a "connection" page, showing publications Gustavo Leone has written about Mice, Knockout.
Connection Strength
1.496
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Evaluating the efficacy of enzalutamide and the development of resistance in a preclinical mouse model of type-I endometrial carcinoma. Neoplasia. 2020 10; 22(10):484-496.
Score: 0.128
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Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation. Cell Rep. 2019 06 18; 27(12):3547-3560.e5.
Score: 0.118
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Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma. J Clin Invest. 2017 Mar 01; 127(3):830-842.
Score: 0.100
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E2f3 in tumor macrophages promotes lung metastasis. Oncogene. 2016 07 14; 35(28):3636-46.
Score: 0.092
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Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles. Nat Cell Biol. 2015 Aug; 17(8):1036-48.
Score: 0.090
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Atypical E2F repressors and activators coordinate placental development. Dev Cell. 2012 Apr 17; 22(4):849-62.
Score: 0.072
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Cell proliferation in the absence of E2F1-3. Dev Biol. 2011 Mar 01; 351(1):35-45.
Score: 0.066
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E2f1-3 are critical for myeloid development. J Biol Chem. 2011 Feb 11; 286(6):4783-95.
Score: 0.065
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E2f3a and E2f3b contribute to the control of cell proliferation and mouse development. Mol Cell Biol. 2009 Jan; 29(2):414-24.
Score: 0.057
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Mouse development with a single E2F activator. Nature. 2008 Aug 28; 454(7208):1137-41.
Score: 0.055
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E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop. Mol Cell Biol. 2007 Jan; 27(1):65-78.
Score: 0.050
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Rb is critical in a mammalian tissue stem cell population. Genes Dev. 2007 Jan 01; 21(1):85-97.
Score: 0.050
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Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb-deficient mice. Proc Natl Acad Sci U S A. 2003 May 27; 100(11):6546-51.
Score: 0.039
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Inactivation of E2F3 results in centrosome amplification. Cancer Cell. 2003 Apr; 3(4):333-46.
Score: 0.038
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Extra-embryonic function of Rb is essential for embryonic development and viability. Nature. 2003 Feb 27; 421(6926):942-7.
Score: 0.038
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The E2F1-3 transcription factors are essential for cellular proliferation. Nature. 2001 Nov 22; 414(6862):457-62.
Score: 0.035
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Myc requires distinct E2F activities to induce S phase and apoptosis. Mol Cell. 2001 Jul; 8(1):105-13.
Score: 0.034
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Loss of PTEN Accelerates NKX3.1 Degradation to Promote Prostate Cancer Progression. Cancer Res. 2019 08 15; 79(16):4124-4134.
Score: 0.030
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hsa-mir183/EGR1-mediated regulation of E2F1 is required for CML stem/progenitor cell survival. Blood. 2018 04 05; 131(14):1532-1544.
Score: 0.027
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Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway. J Clin Invest. 2018 01 02; 128(1):402-414.
Score: 0.027
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NF-?B regulates GDF-15 to suppress macrophage surveillance during early tumor development. J Clin Invest. 2017 Oct 02; 127(10):3796-3809.
Score: 0.026
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Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia. Neoplasia. 2016 09; 18(9):541-52.
Score: 0.024
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Synergistic functions of E2F7 and E2F8 are critical to suppress stress-induced skin cancer. Oncogene. 2017 02 09; 36(6):829-839.
Score: 0.024
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A retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene-targeted mice. Mol Cell Biol. 2014 Jun; 34(11):2029-45.
Score: 0.021
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Stat5 regulates the phosphatidylinositol 3-kinase/Akt1 pathway during mammary gland development and tumorigenesis. Mol Cell Biol. 2014 Apr; 34(7):1363-77.
Score: 0.020
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Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320. Nat Cell Biol. 2011 Dec 18; 14(2):159-67.
Score: 0.018
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The retinoblastoma tumor suppressor regulates a xenobiotic detoxification pathway. PLoS One. 2011; 6(10):e26019.
Score: 0.017
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Division and apoptosis of E2f-deficient retinal progenitors. Nature. 2009 Dec 17; 462(7275):925-9.
Score: 0.015
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Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis. Blood. 2009 Jul 30; 114(5):1123-30.
Score: 0.015
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Targeted deletion of Prkar1a reveals a role for protein kinase A in mesenchymal-to-epithelial transition. Cancer Res. 2008 Apr 15; 68(8):2671-7.
Score: 0.014
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An imaging workflow for characterizing phenotypical change in large histological mouse model datasets. J Biomed Inform. 2008 Dec; 41(6):863-73.
Score: 0.014
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Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development. Dev Cell. 2008 Jan; 14(1):62-75.
Score: 0.013
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Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis. Blood. 2008 Jan 15; 111(2):816-28.
Score: 0.013
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Intestinal hyperplasia induced by simian virus 40 large tumor antigen requires E2F2. J Virol. 2007 Dec; 81(23):13191-9.
Score: 0.013
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Rb-mediated neuronal differentiation through cell-cycle-independent regulation of E2f3a. PLoS Biol. 2007 Jul; 5(7):e179.
Score: 0.013
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Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions. Mol Cell Biol. 2007 Jul; 27(13):4825-43.
Score: 0.013
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Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages. Nature. 2004 Dec 23; 432(7020):1040-5.
Score: 0.011