Gustavo Leone to Humans
This is a "connection" page, showing publications Gustavo Leone has written about Humans.
Connection Strength
0.527
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The broken cycle: E2F dysfunction in?cancer. Nat Rev Cancer. 2019 06; 19(6):326-338.
Score: 0.025
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Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation. Dev Cell. 2017 05 22; 41(4):392-407.e6.
Score: 0.022
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annoPeak: a web application to annotate and visualize peaks from ChIP-seq/ChIP-exo-seq. Bioinformatics. 2017 May 15; 33(10):1570-1571.
Score: 0.022
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Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma. J Clin Invest. 2017 Mar 01; 127(3):830-842.
Score: 0.021
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E2f8 mediates tumor suppression in postnatal liver development. J Clin Invest. 2016 08 01; 126(8):2955-69.
Score: 0.021
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The Spectrum of E2F in Liver Disease--Mediated Regulation in Biology and Cancer. J Cell Physiol. 2016 Jul; 231(7):1438-49.
Score: 0.020
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E2f3 in tumor macrophages promotes lung metastasis. Oncogene. 2016 07 14; 35(28):3636-46.
Score: 0.020
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Selective roles of E2Fs for ErbB2- and Myc-mediated mammary tumorigenesis. Oncogene. 2015 Jan 02; 34(1):119-28.
Score: 0.017
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Emerging roles of E2Fs in cancer: an exit from cell cycle control. Nat Rev Cancer. 2009 Nov; 9(11):785-97.
Score: 0.013
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Pten in stromal fibroblasts suppresses mammary epithelial tumours. Nature. 2009 Oct 22; 461(7267):1084-91.
Score: 0.013
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Direct evidence for epithelial-mesenchymal transitions in breast cancer. Cancer Res. 2008 Feb 01; 68(3):937-45.
Score: 0.011
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Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis. Proc Natl Acad Sci U S A. 2007 Sep 25; 104(39):15400-5.
Score: 0.011
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Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation. J Biol Chem. 2005 May 06; 280(18):18211-20.
Score: 0.009
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Origin, activation and heterogeneity of fibroblasts associated with pancreas and breast cancers. Adv Cancer Res. 2022; 154:169-201.
Score: 0.008
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Imaging Mass Spectrometry Reveals Alterations in N-Linked Glycosylation That Are Associated With Histopathological Changes in Nonalcoholic Steatohepatitis in Mouse and Human. Mol Cell Proteomics. 2022 05; 21(5):100225.
Score: 0.008
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Non-phosphorylatable cyclin D1 mutant potentiates endometrial hyperplasia and drives carcinoma with Pten loss. Oncogene. 2022 04; 41(15):2187-2195.
Score: 0.008
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RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site. Cell Rep. 2021 11 02; 37(5):109934.
Score: 0.007
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Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome. Circ Res. 2021 09 17; 129(7):735-750.
Score: 0.007
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Nuclear PFKP promotes CXCR4-dependent infiltration by T cell acute lymphoblastic leukemia. J Clin Invest. 2021 08 16; 131(16).
Score: 0.007
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T-cell apoptosis induced by granulocyte colony-stimulating factor is associated with retinoblastoma protein phosphorylation and reduced expression of cyclin-dependent kinase inhibitors. Exp Hematol. 2001 Apr; 29(4):401-15.
Score: 0.007
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Stromal Platelet-Derived Growth Factor Receptor-? Signaling Promotes Breast Cancer Metastasis in the Brain. Cancer Res. 2021 02 01; 81(3):606-618.
Score: 0.007
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Cyclin D-CDK4/6 functions in cancer. Adv Cancer Res. 2020; 148:147-169.
Score: 0.007
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PTEN in the Stroma. Cold Spring Harb Perspect Med. 2019 10 01; 9(10).
Score: 0.006
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Modeling Human Cancer-induced Cachexia. Cell Rep. 2019 08 06; 28(6):1612-1622.e4.
Score: 0.006
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Abrupt involution induces inflammation, estrogenic signaling, and hyperplasia linking lack of breastfeeding with increased risk of breast cancer. Breast Cancer Res. 2019 07 17; 21(1):80.
Score: 0.006
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Loss of PTEN Accelerates NKX3.1 Degradation to Promote Prostate Cancer Progression. Cancer Res. 2019 08 15; 79(16):4124-4134.
Score: 0.006
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Cyclin F Controls Cell-Cycle Transcriptional Outputs by Directing the Degradation of the Three Activator E2Fs. Mol Cell. 2019 06 20; 74(6):1264-1277.e7.
Score: 0.006
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Expression of p15(INK4B) in hematopoietic progenitors. Haematologica. 1999; 84(E-letters):E01.
Score: 0.006
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Stromal PTEN determines mammary epithelial response to radiotherapy. Nat Commun. 2018 07 17; 9(1):2783.
Score: 0.006
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Crosstalk between PKCa and PI3K/AKT Signaling Is Tumor Suppressive in the Endometrium. Cell Rep. 2018 07 17; 24(3):655-669.
Score: 0.006
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E2F3 activity is regulated during the cell cycle and is required for the induction of S phase. Genes Dev. 1998 Jul 15; 12(14):2120-30.
Score: 0.006
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A hedgehog pathway-dependent gene signature is associated with poor clinical outcomes in Luminal A breast cancer. Breast Cancer Res Treat. 2018 Jun; 169(3):457-467.
Score: 0.006
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hsa-mir183/EGR1-mediated regulation of E2F1 is required for CML stem/progenitor cell survival. Blood. 2018 04 05; 131(14):1532-1544.
Score: 0.006
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IL-18 Drives ILC3 Proliferation and Promotes IL-22 Production via NF-?B. J Immunol. 2017 10 01; 199(7):2333-2342.
Score: 0.006
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Exosome-Derived miR-25-3p and miR-92a-3p Stimulate Liposarcoma Progression. Cancer Res. 2017 07 15; 77(14):3846-3856.
Score: 0.005
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Stromal PDGFR-a Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth. Neoplasia. 2017 Jun; 19(6):496-508.
Score: 0.005
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Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1. Oncogene. 2017 04 20; 36(16):2297-2308.
Score: 0.005
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Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia. Neoplasia. 2016 09; 18(9):541-52.
Score: 0.005
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RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation. J Clin Invest. 2016 10 03; 126(10):3739-3757.
Score: 0.005
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Synergistic functions of E2F7 and E2F8 are critical to suppress stress-induced skin cancer. Oncogene. 2017 02 09; 36(6):829-839.
Score: 0.005
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Effect of all-trans retinoic acid on procoagulant and fibrinolytic activities of cultured blast cells from patients with acute promyelocytic leukemia. Blood. 1995 Nov 01; 86(9):3535-41.
Score: 0.005
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PTEN is a negative regulator of NK cell cytolytic function. J Immunol. 2015 Feb 15; 194(4):1832-40.
Score: 0.005
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CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth. Oncogene. 2015 Jul; 34(28):3651-61.
Score: 0.005
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Allele-specific loss and transcription of the miR-15a/16-1 cluster in chronic lymphocytic leukemia. Leukemia. 2015 Jan; 29(1):86-95.
Score: 0.004
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HO-3867, a safe STAT3 inhibitor, is selectively cytotoxic to ovarian cancer. Cancer Res. 2014 Apr 15; 74(8):2316-27.
Score: 0.004
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Reovirus protein sigma 1: from cell attachment to protein oligomerization and folding mechanisms. Bioessays. 1994 Mar; 16(3):199-206.
Score: 0.004
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Stat5 regulates the phosphatidylinositol 3-kinase/Akt1 pathway during mammary gland development and tumorigenesis. Mol Cell Biol. 2014 Apr; 34(7):1363-77.
Score: 0.004
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QChIPat: a quantitative method to identify distinct binding patterns for two biological ChIP-seq samples in different experimental conditions. BMC Genomics. 2013; 14 Suppl 8:S3.
Score: 0.004
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Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer. PLoS One. 2013; 8(8):e71533.
Score: 0.004
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A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta. PLoS Biol. 2013; 11(4):e1001536.
Score: 0.004
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Opposing regulation of Sox2 by cell-cycle effectors E2f3a and E2f3b in neural stem cells. Cell Stem Cell. 2013 Apr 04; 12(4):440-52.
Score: 0.004
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E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1. EMBO J. 2012 Oct 03; 31(19):3871-84.
Score: 0.004
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Evidence for a stepwise program of extrathymic T cell development within the human tonsil. J Clin Invest. 2012 Apr; 122(4):1403-15.
Score: 0.004
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Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320. Nat Cell Biol. 2011 Dec 18; 14(2):159-67.
Score: 0.004
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S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways. Cancer Res. 2012 Feb 01; 72(3):604-15.
Score: 0.004
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Pten in the breast tumor microenvironment: modeling tumor-stroma coevolution. Cancer Res. 2011 Feb 15; 71(4):1203-7.
Score: 0.004
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Non-parametric population analysis of cellular phenotypes. Med Image Comput Comput Assist Interv. 2011; 14(Pt 2):343-51.
Score: 0.003
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The Ras oncogene signals centrosome amplification in mammary epithelial cells through cyclin D1/Cdk4 and Nek2. Oncogene. 2010 Sep 09; 29(36):5103-12.
Score: 0.003
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An ets2-driven transcriptional program in tumor-associated macrophages promotes tumor metastasis. Cancer Res. 2010 Feb 15; 70(4):1323-33.
Score: 0.003
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E2F3 is a mediator of DNA damage-induced apoptosis. Mol Cell Biol. 2010 Jan; 30(2):524-36.
Score: 0.003
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Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer. Mol Cancer Ther. 2009 Nov; 8(11):3117-29.
Score: 0.003
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Genomic alterations in tumor stroma. Cancer Res. 2009 Sep 01; 69(17):6759-64.
Score: 0.003
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Atypical E2Fs: new players in the E2F transcription factor family. Trends Cell Biol. 2009 Mar; 19(3):111-8.
Score: 0.003
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Targeted deletion of Prkar1a reveals a role for protein kinase A in mesenchymal-to-epithelial transition. Cancer Res. 2008 Apr 15; 68(8):2671-7.
Score: 0.003
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Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis. Blood. 2008 Jan 15; 111(2):816-28.
Score: 0.003
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CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells. PLoS Genet. 2007 Sep; 3(9):1757-69.
Score: 0.003
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E2F-8: an E2F family member with a similar organization of DNA-binding domains to E2F-7. Oncogene. 2005 Jul 21; 24(31):5000-4.
Score: 0.002
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Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages. Nature. 2004 Dec 23; 432(7020):1040-5.
Score: 0.002
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A NotI-EcoRV promoter library for studies of genetic and epigenetic alterations in mouse models of human malignancies. Genomics. 2004 Oct; 84(4):647-60.
Score: 0.002
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Aberrant regulation of survivin by the RB/E2F family of proteins. J Biol Chem. 2004 Sep 24; 279(39):40511-20.
Score: 0.002
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Bone morphogenetic protein 3B silencing in non-small-cell lung cancer. Oncogene. 2004 Apr 29; 23(20):3521-9.
Score: 0.002
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Distinct capacities of individual E2Fs to induce cell cycle re-entry in postmitotic lens fiber cells of transgenic mice. Dev Neurosci. 2004; 26(5-6):435-45.
Score: 0.002
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Hypermethylation of GpG islands in the promoter region of p15(INK4b) in acute promyelocytic leukemia represses p15(INK4b) expression and correlates with poor prognosis. Leukemia. 2003 May; 17(5):919-24.
Score: 0.002
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Structural characterization of Rasgrf1 and a novel linked imprinted locus. Gene. 2002 May 29; 291(1-2):287-97.
Score: 0.002
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BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia. Proc Natl Acad Sci U S A. 2001 Nov 20; 98(24):13901-6.
Score: 0.002
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Expression of p15(ink4b) gene during megakaryocytic differentiation of normal and myelodysplastic hematopoietic progenitors. Blood. 2001 Jul 15; 98(2):495-7.
Score: 0.002
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Expression of the c-met proto-oncogene and its ligand, hepatocyte growth factor, in Hodgkin disease. Blood. 2001 Feb 15; 97(4):1063-9.
Score: 0.002
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Transient ectopic expression of PTEN in thyroid cancer cell lines induces cell cycle arrest and cell type-dependent cell death. Hum Mol Genet. 2001 Feb 01; 10(3):251-8.
Score: 0.002
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High cyclin-dependent kinase inhibitors in Bcl-2 and Bcl-xL-expressing CD34+-proliferating haematopoietic progenitors. Br J Haematol. 2000 Sep; 110(3):654-62.
Score: 0.002
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Modulation of bcl-2 and p27 in human primitive proliferating hematopoietic progenitors by autocrine TGF-beta1 is a cell cycle-independent effect and influences their hematopoietic potential. Blood. 2000 May 15; 95(10):3001-9.
Score: 0.002
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Expression of cyclin-dependent kinase inhibitor p15(INK4B) during normal and leukemic myeloid differentiation. Exp Hematol. 2000 May; 28(5):519-26.
Score: 0.002
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Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells. Proc Natl Acad Sci U S A. 1998 Mar 31; 95(7):3603-8.
Score: 0.001
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Role of the Rb/E2F pathway in cell growth control. J Cell Physiol. 1997 Nov; 173(2):233-6.
Score: 0.001
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Expression of the HsOrc1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factor. Mol Cell Biol. 1996 Dec; 16(12):6977-84.
Score: 0.001
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[The relationship between immunological defence and the development of tumours]. Arch Sci Med (Torino). 1973 Oct-Dec; 130(4):273-82.
Score: 0.001