John O'Bryan to ras Proteins
This is a "connection" page, showing publications John O'Bryan has written about ras Proteins.
Connection Strength
5.013
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Probing RAS Function with Monobodies. Methods Mol Biol. 2021; 2262:281-302.
Score: 0.665
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Inhibition of RAS: proven and potential vulnerabilities. Biochem Soc Trans. 2020 10 30; 48(5):1831-1841.
Score: 0.657
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Biology, pathology, and therapeutic targeting of RAS. Adv Cancer Res. 2020; 148:69-146.
Score: 0.643
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Therapeutic targeting of RAS: New hope for drugging the "undruggable". Biochim Biophys Acta Mol Cell Res. 2020 02; 1867(2):118570.
Score: 0.613
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Pharmacological targeting of RAS: Recent success with direct inhibitors. Pharmacol Res. 2019 01; 139:503-511.
Score: 0.572
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Direct inhibition of RAS: Quest for the Holy Grail? Semin Cancer Biol. 2019 02; 54:138-148.
Score: 0.539
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Inhibition of RAS function through targeting an allosteric regulatory site. Nat Chem Biol. 2017 Jan; 13(1):62-68.
Score: 0.499
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A new dimension to Ras function: a novel role for nucleotide-free Ras in Class II phosphatidylinositol 3-kinase beta (PI3KC2?) regulation. PLoS One. 2012; 7(9):e45360.
Score: 0.374
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Intersectin activates Ras but stimulates transcription through an independent pathway involving JNK. J Biol Chem. 2003 Nov 21; 278(47):47038-45.
Score: 0.200
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Targeting the "undruggable" RAS with biologics. Adv Cancer Res. 2022; 153:237-266.
Score: 0.174
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Intersectin can regulate the Ras/MAP kinase pathway independent of its role in endocytosis. J Biol Chem. 2000 Sep 22; 275(38):29894-9.
Score: 0.041
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The src homology 2 and phosphotyrosine binding domains of the ShcC adaptor protein function as inhibitors of mitogenic signaling by the epidermal growth factor receptor. J Biol Chem. 1998 Aug 07; 273(32):20431-7.
Score: 0.035