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    • IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer.
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IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer.

IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer. Gut. 2018 02; 67(2):320-332.

View in: PubMed

subject areas
  • Actins
  • Animals
  • Antineoplastic Agents, Immunological
  • Antineoplastic Combined Chemotherapy Protocols
  • B7-H1 Antigen
  • Carcinoma, Pancreatic Ductal
  • Disease Models, Animal
  • Disease Progression
  • Female
  • Humans
  • Hyaluronan Receptors
  • Interleukin-6
  • Janus Kinases
  • L-Selectin
  • Lymphocytes, Tumor-Infiltrating
  • Mice
  • Mice, Inbred C57BL
  • Pancreatic Neoplasms
  • Pancreatic Stellate Cells
  • STAT Transcription Factors
  • Survival Rate
  • Th1 Cells
  • Tumor Microenvironment
  • Xenograft Model Antitumor Assays

authors with profiles
  • Michael C Ostrowski