Robert E. Notari

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InstitutionMedical University of South Carolina
DepartmentSCCP Drug Discovery and Biomedical Sciences - MUSC Campus
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dyar SC, Notari RE, Dyar SC, Notari RE. A nomogram to evaluate intrinsic absorption rate constants of potential oral prolonged-release candidates. Pharm Dev Technol. 1999 Aug; 4(3):305-12. PMID: 10434276.
      Citations:    Fields:    Translation:Cells
    2. Fubara JO, Notari RE, Fubara JO, Notari RE. Influence of pH, temperature and buffers on cefepime degradation kinetics and stability predictions in aqueous solutions. J Pharm Sci. 1998 Dec; 87(12):1572-6. PMID: 10189269.
      Citations: 4     Fields:    Translation:Cells
    3. Fubara JO, Notari RE, Fubara JO, Notari RE. A kinetic oxymoron: concentration-dependent first-order rate constants for hydrolysis of ceftazidime. J Pharm Sci. 1998 Jan; 87(1):53-8. PMID: 9452968.
      Citations: 3     Fields:    Translation:Cells
    4. Zhou M, Notari RE, Zhou M, Notari RE. A nomogram to predict the best biological half-life values for candidates for oral prolonged-release formulations. J Pharm Sci. 1996 Aug; 85(8):791-5. PMID: 8863265.
      Citations:    Fields:    Translation:Humans
    5. Zhou M, Notari RE, Zhou M, Notari RE. Methodology for using oral dose pharmacokinetic data to select drugs for prolonged release formulations and validation of the method using simulated data. Biopharm Drug Dispos. 1995 May; 16(4):319-31. PMID: 7548781.
      Citations:    Fields:    
    6. Zhou M, Notari RE, Zhou M, Notari RE. Influence of pH, temperature, and buffers on the kinetics of ceftazidime degradation in aqueous solutions. J Pharm Sci. 1995 May; 84(5):534-8. PMID: 7658340.
      Citations: 5     Fields:    Translation:Cells
    7. Wang D, Notari RE, Wang D, Notari RE. Cefuroxime hydrolysis kinetics and stability predictions in aqueous solution. J Pharm Sci. 1994 Apr; 83(4):577-81. PMID: 8046618.
      Citations: 1     Fields:    Translation:Cells
    8. Lam CF, Jiang Q, Notari RE, Lam CF, Jiang Q, Notari RE. An efficient method for computer-aided dosage form design. Comput Biol Med. 1993 Nov; 23(6):475-82. PMID: 8306626.
      Citations:    Fields:    
    9. Orr RK, Hoehn JL, Col NF, Irvin JR, Notari RE. Computer-aided dosage form design. III. Feasibility assessment for an oral prolonged-release phenytoin product. Pharm Res. 1991 Feb; 8(2):232-7. PMID: 2023873.
      Citations:    Fields:    Translation:HumansCells
    10. Orr RK, Hoehn JL, Col NF, Nguyen NA, Notari RE. Substituent effects on degradation rates and pathways of cytosine nucleosides. J Pharm Sci. 1989 Oct; 78(10):802-6. PMID: 2600783.
      Citations:    Fields:    Translation:Cells
    11. Pfeifer RW, Notari RE, Pfeifer RW, Notari RE. Predicting caffeine plasma concentrations resulting from consumption of food or beverages: a simple method and its origin. Drug Intell Clin Pharm. 1988 Dec; 22(12):953-9. PMID: 3243174.
      Citations: 4     Fields:    Translation:Humans
    12. Nguyen NA, Notari RE, Nguyen NA, Notari RE. Potential improvement in shelf life using the prodrug approach. II. A systematic examination of kinetic requirements. Pharm Res. 1988 Oct; 5(10):634-8. PMID: 3244615.
      Citations: 1     Fields:    Translation:Cells
    13. Nguyen NA, Mortada LM, Notari RE, Nguyen NA, Mortada LM, Notari RE. Potential improvement in the shelf life of parenterals using the prodrug approach: bacampicillin and talampicillin hydrolysis kinetics and utilization time. Pharm Res. 1988 May; 5(5):288-96. PMID: 3244638.
      Citations: 3     Fields:    Translation:Cells
    14. Lee TY, Notari RE, Lee TY, Notari RE. Computer-aided dosage form design. II. Methods for defining a zero-order sustained-release delivery system of maximum formulating flexibility. Pharm Res. 1987 Oct; 4(5):385-91. PMID: 3508547.
      Citations: 1     Fields:    Translation:Humans
    15. Lee TY, Notari RE, Lee TY, Notari RE. Computer-aided dosage form design. I. Methods for defining a long-acting first-order delivery system of maximum formulating flexibility. Pharm Res. 1987 Aug; 4(4):311-6. PMID: 3508537.
      Citations: 2     Fields:    Translation:Humans
    16. Lee TY, Notari RE, Lee TY, Notari RE. Kinetics and mechanism of captopril oxidation in aqueous solution under controlled oxygen partial pressure. Pharm Res. 1987 Apr; 4(2):98-103. PMID: 3334413.
      Citations: 2     Fields:    Translation:Cells
    17. Pejaver SK, Notari RE, Pejaver SK, Notari RE. Decreased stability in liposomal suspensions: accelerated loss of p-nitrophenyl acetate. J Pharm Sci. 1985 Nov; 74(11):1167-71. PMID: 4087176.
      Citations:    Fields:    Translation:Cells
    18. Notari RE, Notari RE. Theory and practice of prodrug kinetics. Methods Enzymol. 1985; 112:309-23. PMID: 4046852.
      Citations: 1     Fields:    Translation:HumansAnimals
    19. Kirsch LE, Notari RE, Kirsch LE, Notari RE. Aqueous conversion kinetics and mechanisms of ancitabine, a prodrug of the antileukemic agent cytarabine. J Pharm Sci. 1984 Jul; 73(7):896-902. PMID: 6206222.
      Citations: 2     Fields:    Translation:Cells
    20. Kirsch LE, Notari RE, Kirsch LE, Notari RE. Pharmacokinetic prodrug modeling: in vitro and in vivo kinetics and mechanisms of ancitabine bioconversion to cytarabine. J Pharm Sci. 1984 Jun; 73(6):728-32. PMID: 6204036.
      Citations:    Fields:    Translation:HumansAnimalsCells
    21. Kirsch LE, Notari RE, Kirsch LE, Notari RE. Theoretical basis for the detection of general-base catalysis in the presence of predominating hydroxide catalysis. J Pharm Sci. 1984 Jun; 73(6):724-7. PMID: 6737254.
      Citations: 1     Fields:    Translation:Cells
    22. Orr RK, Hoehn JL, Col NF, D'Silva JB, Notari RE. Drug stability in liposomal suspensions: hydrolysis of indomethacin, cyclocytidine, and p-nitrophenyl acetate. J Pharm Sci. 1982 Dec; 71(12):1394-8. PMID: 6185667.
      Citations: 3     Fields:    Translation:Cells
    23. Byron PR, Guest RT, Notari RE, Byron PR, Guest RT, Notari RE. Thermodynamic dependence of interfacial transfer kinetics of nonionized barbituric acid derivatives in two-phase transfer cell. J Pharm Sci. 1981 Nov; 70(11):1265-9. PMID: 7299674.
      Citations: 1     Fields:    Translation:Cells
    24. Notari RE, Notari RE. Prodrug design. Pharmacol Ther. 1981; 14(1):25-53. PMID: 7033999.
      Citations: 6     Fields:    Translation:Cells
    25. Tomlinson E, Notari RE, Byron PR, Tomlinson E, Notari RE, Byron PR. Simultaneous partitioning and hydrolysis kinetics of amoxicillin and ampicillin. J Pharm Sci. 1980 Jun; 69(6):655-8. PMID: 7205576.
      Citations:    Fields:    Translation:Cells
    26. Byron PR, Notari RE, Tomlinson E, Byron PR, Notari RE, Tomlinson E. Calculation of partition coefficient of an unstable compound using kinetic methods. J Pharm Sci. 1980 May; 69(5):527-31. PMID: 7381736.
      Citations: 1     Fields:    Translation:PHPublic Health
    27. D'Silva JB, Notari RE, D'Silva JB, Notari RE. Stability-indicating colorimetric assay for indicine N-oxide using TLC. J Pharm Sci. 1980 Apr; 69(4):471-2. PMID: 7373551.
      Citations:    Fields:    
    28. Byron PR, Notari RE, Tomlinson E, Byron PR, Notari RE, Tomlinson E. Calculation of the partition coefficient of an unstable compound using kinetic methods [proceedings]. J Pharm Pharmacol. 1978 Dec; 30 Suppl:7P. PMID: 32328.
      Citations:    Fields:    
    29. Byron PR, Notari RE, Byron PR, Notari RE. Critical analysis of "flip-flop" phenomenon in two-compartment pharmacokinetic model. J Pharm Sci. 1976 Aug; 65(8):1140-4. PMID: 978432.
      Citations: 10     Fields:    Translation:Cells
    30. Reuning RH, Malspeis L, Frank S, Notari RE, Reuning RH, Malspeis L, Frank S, Notari RE. Testing of drug delivery systems for use in the treatment of narcotic addiction. Natl Inst Drug Abuse Res Monogr Ser. 1976 Jan; (4):43-5. PMID: 823438.
      Citations:    Fields:    Translation:HumansAnimals
    31. Notari RE, DeYoung JL, Notari RE, DeYoung JL. Kinetics and mechanisms of degradation of the antileukemic agent 5-azacytidine in aqueous solutions. J Pharm Sci. 1975 Jul; 64(7):1148-57. PMID: 50433.
      Citations: 31     Fields:    Translation:Cells
    32. Reuning RH, Malspeis L, Frank S, Notari RE, Reuning RH, Malspeis L, Frank S, Notari RE. Testing of drug delivery systems for use in the treatment of narcotic addiction. Natl Inst Drug Abuse Res Monogr Ser. 1975; (4):43-5. PMID: 827709.
      Citations:    Fields:    Translation:HumansAnimalsCells
    33. Notari RE, Kavaliunas DR, Bockbrader HN, Notari RE, Kavaliunas DR, Bockbrader HN. Proceedings: Apparent biological half-life values determined by administration of drug by methods other than rapid intravenous injection. J Pharm Pharmacol. 1974 Dec; 26 Suppl:62P-63P. PMID: 4156741.
      Citations:    Fields:    
    34. Notari RE, Notari RE. Proceedings: Structural effects in pharmacokinetics and drug response. Acta Pharm Suec. 1974 Dec; 11(6):633-5. PMID: 1136785.
      Citations:    Fields:    Translation:HumansAnimals
    35. DeYoung JL, Notari RE, Feller DR, DeYoung JL, Notari RE, Feller DR. Comparative reactivity of cytidine and arabinosylcytosine to their 6-methyl derivatives in the presence of cytidine deaminase. Res Commun Chem Pathol Pharmacol. 1974 Sep; 9(1):163-72. PMID: 4474681.
      Citations:    Fields:    Translation:Animals
    36. Garry PJ, Prince LC, Notari RE, Garry PJ, Prince LC, Notari RE. Half-life of human serum cholinesterase following blood transfusion. Res Commun Chem Pathol Pharmacol. 1974 Jun; 8(2):371-80. PMID: 4852217.
      Citations:    Fields:    Translation:Humans
    37. Notari RE, Notari RE. Pharmacokinetics and molecular modification: implications in drug design and evaluation. J Pharm Sci. 1973 Jun; 62(6):865-81. PMID: 4576424.
      Citations: 10     Fields:    Translation:Animals
    38. Reuning RH, Sams RA, Notari RE, Reuning RH, Sams RA, Notari RE. Role of pharmacokinetics in drug dosage adjustment. I. Pharmacologic effect kinetics and apparent volume of distribution of digoxin. J Clin Pharmacol New Drugs. 1973 Apr; 13(4):127-41. PMID: 4487163.
      Citations: 62     Fields:    Translation:Humans
    39. Notari RE, Witiak DT, DeYoung JL, Lin AJ, Notari RE, Witiak DT, DeYoung JL, Lin AJ. Comparative kinetics of cytosine nucleosides. Influence of a 6-methyl substituent on degradation rates and pathways in aqueous buffers. J Med Chem. 1972 Dec; 15(12):1207-14. PMID: 4635962.
      Citations: 3     Fields:    Translation:Cells
    40. Notari RE, Chin ML, Wittebort R, Notari RE, Chin ML, Wittebort R. Arabinosylcytosine stability in aqueous solutions: pH profile and shelflife predictions. J Pharm Sci. 1972 Aug; 61(8):1189-96. PMID: 5050364.
      Citations: 4     Fields:    Translation:Cells
    41. Notari RE, Baker T, Notari RE, Baker T. Hydroxamic acids. IV. Hydroxide effect in hydroxylaminolysis of ethyl acetate. J Pharm Sci. 1972 Feb; 61(2):244-8. PMID: 5059791.
      Citations:    Fields:    Translation:Cells
    42. Notari RE, DeYoung JL, Reuning RH, Notari RE, DeYoung JL, Reuning RH. Effect of parallel first-order loss from site of administration on calculated values for absorption rate constants. J Pharm Sci. 1972 Jan; 61(1):135-8. PMID: 5058633.
      Citations: 12     Fields:    
    43. Notari RE, Chin ML, Cardoni A, Notari RE, Chin ML, Cardoni A. Intermolecular and intramolecular catalysis in deamination of cytosine nucleosides. J Pharm Sci. 1970 Jan; 59(1):27-32. PMID: 5411321.
      Citations: 4     Fields:    Translation:Cells
    44. Notari RE, Caiola SM, Notari RE, Caiola SM. Catalysis of streptovitacin A dehydration: kinetics and mechanisms. J Pharm Sci. 1969 Oct; 58(10):1203-8. PMID: 5349103.
      Citations: 1     Fields:    Translation:Cells
    45. Notari RE, Notari RE. Hydroxamic acids. 3. Kinetics of acetohydroxamic acid formation from ethyl acetate. J Pharm Sci. 1969 Sep; 58(9):1069-73. PMID: 5346067.
      Citations:    Fields:    
    46. Notari RE, Chin ML, Cardoni A, Notari RE, Chin ML, Cardoni A. Intramolecular participation in the hydrolytic deamination of 1-beta-D-arabinosylcytosine. Tetrahedron Lett. 1969 Sep; (40):3499-502. PMID: 5820945.
      Citations: 1     Fields:    Translation:Cells
    47. Notari RE, Munson JW, Notari RE, Munson JW. Hydroxamic acids. I. Factors affecting the stability of the hydroxamic acid-iron complex. J Pharm Sci. 1969 Sep; 58(9):1060-4. PMID: 5346065.
      Citations: 3     Fields:    
    48. Notari RE, Notari RE. Hydroxamic acids. II. Kinetics and mechanisms of hydroxyaminolysis of succinimide. J Pharm Sci. 1969 Sep; 58(9):1064-8. PMID: 5346066.
      Citations: 1     Fields:    
    49. Notari RE, Notari RE. A mechanism for the hydrolytic deamination of cytosine arabinoside in aqueous buffer. J Pharm Sci. 1967 Jul; 56(7):804-9. PMID: 6034820.
      Citations: 4     Fields:    
    50. Garrett ER, Notari RE, Garrett ER, Notari RE. Cycloheximide transformations. I. Kinetics and mechanisms in aqueous acid. J Org Chem. 1966 Feb; 31(2):425-34. PMID: 5902474.
      Citations:    Fields:    
    51. Notari RE, Sokoloski TD, Notari RE, Sokoloski TD. Kinetics of calcium carbonate neutralization. First-order case of the cube-root law. J Pharm Sci. 1965 Oct; 54(10):1500-4. PMID: 5883225.
      Citations:    Fields:    
    52. Garrett ER, Notari RE, Garrett ER, Notari RE. Determination of cycloheximide and its degradiation products alone and in mixtures. J Pharm Sci. 1965 Apr; 54(4):561-4. PMID: 5842339.
      Citations:    Fields:    
    53. GARRETT ER, NOTARI RE, GARRETT ER, NOTARI RE. CYCOLHEXIMIDE TRANSFORMATIONS. II. KINETICS AND STABILITY IN A PHARMACEUTICALLY USEFUL PH RANGE. J Pharm Sci. 1965 Feb; 54:209-15. PMID: 14301000.
      Citations:    Fields:    
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