Connection

David Priest to Folic Acid

This is a "connection" page, showing publications David Priest has written about Folic Acid.
Connection Strength

1.908
  1. Modulation of fluorouracil antitumor activity by folic acid in a murine model system. Biochem Pharmacol. 1999 Sep 01; 58(5):835-9.
    View in: PubMed
    Score: 0.154
  2. Accumulation of plasma reduced folates after folic acid administration. Semin Oncol. 1999 Apr; 26(2 Suppl 6):38-41.
    View in: PubMed
    Score: 0.149
  3. Effects of antisense-based folypoly-gamma-glutamate synthetase down-regulation on reduced folates and cellular proliferation in CCRF-CEM cells. Biochem Pharmacol. 1998 Jun 15; 55(12):2031-7.
    View in: PubMed
    Score: 0.141
  4. Impact of dietary folic acid on reduced folates in mouse plasma and tissues. Relationship to dideazatetrahydrofolate sensitivity. Biochem Pharmacol. 1994 Jul 19; 48(2):319-25.
    View in: PubMed
    Score: 0.108
  5. Disposition of folic acid and its metabolites: a comparison with leucovorin. Clin Pharmacol Ther. 1994 May; 55(5):501-8.
    View in: PubMed
    Score: 0.106
  6. Folate metabolites as modulators of antitumor drug activity. Adv Exp Med Biol. 1993; 338:693-8.
    View in: PubMed
    Score: 0.097
  7. Relationship of reduced folate changes to inhibition of DNA synthesis induced by methotrexate in L1210 cells in vivo. Cancer Res. 1989 Aug 01; 49(15):4204-9.
    View in: PubMed
    Score: 0.076
  8. The role of cellular folates in the enhancement of activity of the thymidylate synthase inhibitor 10-propargyl-5,8-dideazafolate against hepatoma cells in vitro by inhibitors of dihydrofolate reductase. J Biol Chem. 1989 Jun 25; 264(18):10685-92.
    View in: PubMed
    Score: 0.076
  9. The enhancement of the activity of 10-propargyl-5,8-dideazafolate and 5,10-dideazatetrahydrofolate by inhibitors of dihydrofolate reductase. Adv Enzyme Regul. 1989; 28:13-21.
    View in: PubMed
    Score: 0.073
  10. Biochemical basis for cisplatin and 5-fluorouracil synergism in human ovarian carcinoma cells. Proc Natl Acad Sci U S A. 1986 Dec; 83(23):8923-5.
    View in: PubMed
    Score: 0.064
  11. Tissue folate polyglutamate chain length determination by electrophoresis as thymidylate synthase-fluorodeoxyuridylate ternary complexes. Methods Enzymol. 1986; 122:313-9.
    View in: PubMed
    Score: 0.060
  12. Effects of methotrexate on folates in Krebs ascites and L1210 murine leukemia cells. Cancer Lett. 1986 Jan; 30(1):55-9.
    View in: PubMed
    Score: 0.060
  13. Determination of mouse liver 5-methyltetrahydrofolate concentration and polyglutamate forms. J Biochem Biophys Methods. 1985 Mar; 10(5-6):287-94.
    View in: PubMed
    Score: 0.056
  14. Response of mouse hepatoma cell methylenetetrahydrofolate polyglutamates to folate deprivation. Biochim Biophys Acta. 1983 Apr 20; 756(3):253-7.
    View in: PubMed
    Score: 0.049
  15. The role of multidrug resistance proteins MRP1, MRP2 and MRP3 in cellular folate homeostasis. Biochem Pharmacol. 2003 Mar 01; 65(5):765-71.
    View in: PubMed
    Score: 0.049
  16. Evaluation of folylpolyglutamates by electrophoretic separation of fluorodeoxyuridylate-thymidylate synthase-methylenetetrahydrofolate complexes. Adv Exp Med Biol. 1983; 163:139-48.
    View in: PubMed
    Score: 0.048
  17. Cell cycle patterns of thymidylate synthetase and 5,10-methylenetetrahydrofolate polyglutamates in cultured mouse hepatoma cells. Experientia. 1982 Jan 15; 38(1):88-9.
    View in: PubMed
    Score: 0.045
  18. Tissue folylpolyglutamate chain-length characterization by electrophoresis as thymidylate synthetase-fluorodeoxyuridylate ternary complexes. Anal Biochem. 1981 Jul 15; 115(1):163-9.
    View in: PubMed
    Score: 0.044
  19. Modulation of both endogenous folates and thymidine enhance the therapeutic efficacy of thymidylate synthase inhibitors. Cancer Res. 2001 May 01; 61(9):3675-81.
    View in: PubMed
    Score: 0.043
  20. Purification of mouse liver thymidylate synthetase by affinity chromatography using 10-methyl-5,8-dideazafolate as the affinant. Experientia. 1981 Feb 15; 37(2):119-20.
    View in: PubMed
    Score: 0.043
  21. Electrophoretic identification of poly-gamma-glutamate chain-lengths of 5,10-methylenetetrahydrofolate using thymidylate synthetase complexes. J Biochem Biophys Methods. 1980 Oct; 3(4):201-6.
    View in: PubMed
    Score: 0.041
  22. Multiple mechanisms of resistance to polyglutamatable and lipophilic antifolates in mammalian cells: role of increased folylpolyglutamylation, expanded folate pools, and intralysosomal drug sequestration. Mol Pharmacol. 1999 Apr; 55(4):761-9.
    View in: PubMed
    Score: 0.037
  23. A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance. J Biol Chem. 1998 Nov 13; 273(46):30189-98.
    View in: PubMed
    Score: 0.036
  24. Disposition of leucovorin and its metabolites in dietary folic acid-deplete mice - comparison between tumor, liver, and plasma. Cancer Chemother Pharmacol. 1997; 40(2):126-30.
    View in: PubMed
    Score: 0.032
  25. Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and-resistant leukemia cells. Adv Enzyme Regul. 1997; 37:59-76.
    View in: PubMed
    Score: 0.032
  26. Growth of ovarian-carcinoma cell lines at physiological folate concentration: effect on folate-binding protein expression in vitro and in vivo. Int J Cancer. 1995 Nov 03; 63(3):395-401.
    View in: PubMed
    Score: 0.029
  27. Disposition of leucovorin and its metabolites in the plasma, intestinal epithelium, and intraperitoneal L1210 cells of methotrexate-pretreated mice. Cancer Chemother Pharmacol. 1994; 34(6):455-8.
    View in: PubMed
    Score: 0.026
  28. Altered transport of folic acid and antifolates through the carrier mediated reduced folate transport system in a human leukemia cell line resistant to (6R) 5,10-dideazatetrahydrofolic acid (DDATHF). Adv Exp Med Biol. 1993; 338:775-8.
    View in: PubMed
    Score: 0.024
  29. The effect of methotrexate on the folate coenzyme pools in human hepatoma cells in culture. Adv Exp Med Biol. 1991; 309A:75-8.
    View in: PubMed
    Score: 0.021
  30. Role of substrate depletion in the inhibition of thymidylate biosynthesis by the dihydrofolate reductase inhibitor trimetrexate in cultured hepatoma cells. Cancer Res. 1990 Jul 01; 50(13):3979-84.
    View in: PubMed
    Score: 0.020
  31. Role of methylenetetrahydrofolate depletion in methotrexate-mediated intracellular thymidylate synthesis inhibition in cultured L1210 cells. Cancer Res. 1988 Jun 15; 48(12):3398-404.
    View in: PubMed
    Score: 0.018
  32. The role of folylpolyglutamate synthetase and gamma-glutamyl hydrolase in altering cellular folyl- and antifolylpolyglutamates. Adv Enzyme Regul. 1987; 26:147-55.
    View in: PubMed
    Score: 0.016
  33. Effects of growth rate and methotrexate on folate polyglutamates and folylpolyglutamate hydrolase activity in Krebs ascites cells. Biochem Cell Biol. 1986 Apr; 64(4):363-7.
    View in: PubMed
    Score: 0.015
  34. Comparison of folylpolyglutamate hydrolases of mouse liver, kidney, muscle and brain. Mol Cell Biochem. 1982 Mar 19; 43(2):81-7.
    View in: PubMed
    Score: 0.011
  35. The effect of methionine on methotrexate metabolism in rat hepatocytes in monolayer culture. Biochim Biophys Acta. 1989 May 10; 1011(2-3):122-8.
    View in: PubMed
    Score: 0.005
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.