Connection

David Priest to Thymidylate Synthase

This is a "connection" page, showing publications David Priest has written about Thymidylate Synthase.
Connection Strength

0.736
  1. The role of cellular folates in the enhancement of activity of the thymidylate synthase inhibitor 10-propargyl-5,8-dideazafolate against hepatoma cells in vitro by inhibitors of dihydrofolate reductase. J Biol Chem. 1989 Jun 25; 264(18):10685-92.
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    Score: 0.081
  2. Tissue folate polyglutamate chain length determination by electrophoresis as thymidylate synthase-fluorodeoxyuridylate ternary complexes. Methods Enzymol. 1986; 122:313-9.
    View in: PubMed
    Score: 0.064
  3. Evaluation of folylpolyglutamates by electrophoretic separation of fluorodeoxyuridylate-thymidylate synthase-methylenetetrahydrofolate complexes. Adv Exp Med Biol. 1983; 163:139-48.
    View in: PubMed
    Score: 0.052
  4. Cell cycle patterns of thymidylate synthetase and 5,10-methylenetetrahydrofolate polyglutamates in cultured mouse hepatoma cells. Experientia. 1982 Jan 15; 38(1):88-9.
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    Score: 0.049
  5. Relative affinity of 5,10-methylenetetrahydrofolylpolyglutamates for the Lactobacillus casei thymidylate synthetase-5-fluorodeoxyuridylate binary complex. Arch Biochem Biophys. 1981 Aug; 210(1):118-23.
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    Score: 0.047
  6. Tissue folylpolyglutamate chain-length characterization by electrophoresis as thymidylate synthetase-fluorodeoxyuridylate ternary complexes. Anal Biochem. 1981 Jul 15; 115(1):163-9.
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    Score: 0.047
  7. Modulation of both endogenous folates and thymidine enhance the therapeutic efficacy of thymidylate synthase inhibitors. Cancer Res. 2001 May 01; 61(9):3675-81.
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    Score: 0.046
  8. Purification of mouse liver thymidylate synthetase by affinity chromatography using 10-methyl-5,8-dideazafolate as the affinant. Experientia. 1981 Feb 15; 37(2):119-20.
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    Score: 0.046
  9. Electrophoretic identification of poly-gamma-glutamate chain-lengths of 5,10-methylenetetrahydrofolate using thymidylate synthetase complexes. J Biochem Biophys Methods. 1980 Oct; 3(4):201-6.
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    Score: 0.044
  10. Increased thymidylate synthetase in 5-fluorodeoxyuridine resistant cultured hepatoma cells. Biochem Pharmacol. 1980 Jun 01; 29(11):1549-53.
    View in: PubMed
    Score: 0.043
  11. A centrifugal column assay for thymidylate synthetase using the active site titrant 5-fluoro-2'-deoxyuridylate. Anal Biochem. 1980 Mar 15; 103(1):51-4.
    View in: PubMed
    Score: 0.043
  12. Rapid quantitative PCR for determination of relative gene expressions in tissue specimens. PCR Methods Appl. 1995 Apr; 4(5):305-8.
    View in: PubMed
    Score: 0.030
  13. A sensitive radioenzymatic assay for (S)-5-formyltetrahydrofolate. Anal Biochem. 1991 Aug 01; 196(2):284-9.
    View in: PubMed
    Score: 0.024
  14. Role of folylpolyglutamates in biochemical modulation of fluoropyrimidines by leucovorin. Cancer Res. 1991 Feb 01; 51(3):789-93.
    View in: PubMed
    Score: 0.023
  15. Inhibition of mammalian thymidylate synthase by 10-formyltetrahydropteroylpolyglutamate. Arch Biochem Biophys. 1991 Jan; 284(1):219-22.
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    Score: 0.023
  16. Role of substrate depletion in the inhibition of thymidylate biosynthesis by the dihydrofolate reductase inhibitor trimetrexate in cultured hepatoma cells. Cancer Res. 1990 Jul 01; 50(13):3979-84.
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    Score: 0.022
  17. Role of methylenetetrahydrofolate depletion in methotrexate-mediated intracellular thymidylate synthesis inhibition in cultured L1210 cells. Cancer Res. 1988 Jun 15; 48(12):3398-404.
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    Score: 0.019
  18. Biochemical basis for cisplatin and 5-fluorouracil synergism in human ovarian carcinoma cells. Proc Natl Acad Sci U S A. 1986 Dec; 83(23):8923-5.
    View in: PubMed
    Score: 0.017
  19. Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and-resistant leukemia cells. Adv Enzyme Regul. 1997; 37:59-76.
    View in: PubMed
    Score: 0.009
  20. Multifactorial resistance to 5,10-dideazatetrahydrofolic acid in cell lines derived from human lymphoblastic leukemia CCRF-CEM. Cancer Res. 1995 Feb 01; 55(3):566-73.
    View in: PubMed
    Score: 0.008
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.