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    • SLC36A1-mTORC1 signaling drives acquired resistance to CDK4/6 inhibitors.
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SLC36A1-mTORC1 signaling drives acquired resistance to CDK4/6 inhibitors.

SLC36A1-mTORC1 signaling drives acquired resistance to CDK4/6 inhibitors. Sci Adv. 2019 09; 5(9):eaax6352.

View in: PubMed

subject areas
  • Amino Acid Transport Systems
  • Cell Line, Tumor
  • Cyclin-Dependent Kinase 4
  • Cyclin-Dependent Kinase 6
  • Drug Resistance, Neoplasm
  • Humans
  • Mechanistic Target of Rapamycin Complex 1
  • Melanoma, Experimental
  • Neoplasm Proteins
  • Protein Kinase Inhibitors
  • Signal Transduction
  • Symporters
  • Xenograft Model Antitumor Assays

authors with profiles
  • John Mcelmurray Wrangle