Connection

Carol Feghali-Bostwick to Fibroblasts

This is a "connection" page, showing publications Carol Feghali-Bostwick has written about Fibroblasts.
Connection Strength

7.646
  1. PDGF Promotes Dermal Fibroblast Activation via a Novel Mechanism Mediated by Signaling Through MCHR1. Front Immunol. 2021; 12:745308.
    View in: PubMed
    Score: 0.538
  2. Antifibrotic factor KLF4 is repressed by the miR-10/TFAP2A/TBX5 axis in dermal fibroblasts: insights from twins discordant for systemic sclerosis. Ann Rheum Dis. 2022 02; 81(2):268-277.
    View in: PubMed
    Score: 0.536
  3. Phenotypic Characterization of Transgenic Mice Expressing Human IGFBP-5. Int J Mol Sci. 2020 Dec 30; 22(1).
    View in: PubMed
    Score: 0.505
  4. Insulin-like growth factor (IGF)-II- mediated fibrosis in pathogenic lung conditions. PLoS One. 2019; 14(11):e0225422.
    View in: PubMed
    Score: 0.468
  5. The membrane-associated adaptor protein DOK5 is upregulated in systemic sclerosis and associated with IGFBP-5-induced fibrosis. PLoS One. 2014; 9(2):e87754.
    View in: PubMed
    Score: 0.313
  6. Antifibrotic effects of roscovitine in normal and scleroderma fibroblasts. PLoS One. 2012; 7(11):e48560.
    View in: PubMed
    Score: 0.288
  7. The pro-fibrotic factor IGFBP-5 induces lung fibroblast and mononuclear cell migration. Am J Respir Cell Mol Biol. 2009 Aug; 41(2):179-88.
    View in: PubMed
    Score: 0.220
  8. Monozygotic twins clinically discordant for scleroderma show concordance for fibroblast gene expression profiles. Arthritis Rheum. 2005 Oct; 52(10):3305-14.
    View in: PubMed
    Score: 0.175
  9. Reduced Cathepsin L expression and secretion into the extracellular milieu contribute to lung fibrosis in systemic sclerosis. Rheumatology (Oxford). 2023 03 01; 62(3):1306-1316.
    View in: PubMed
    Score: 0.147
  10. First Characterization of the Transcriptome of Lung Fibroblasts of SSc Patients and Healthy Donors of African Ancestry. Int J Mol Sci. 2023 Feb 11; 24(4).
    View in: PubMed
    Score: 0.146
  11. Vaccination-based immunotherapy to target profibrotic cells in liver and lung. Cell Stem Cell. 2022 10 06; 29(10):1459-1474.e9.
    View in: PubMed
    Score: 0.142
  12. Identification of Impacted Pathways and Transcriptomic Markers as Potential Mediators of Pulmonary Fibrosis in Transgenic Mice Expressing Human IGFBP5. Int J Mol Sci. 2021 Nov 22; 22(22).
    View in: PubMed
    Score: 0.134
  13. Systemic sclerosis biomarkers detection in the secretome of TGF?1-activated primary human lung fibroblasts. J Proteomics. 2021 06 30; 242:104243.
    View in: PubMed
    Score: 0.129
  14. Elucidating the cellular mechanism for E2-induced dermal fibrosis. Arthritis Res Ther. 2021 02 27; 23(1):68.
    View in: PubMed
    Score: 0.128
  15. Differential DNA Methylation Landscape in Skin Fibroblasts from African Americans with Systemic Sclerosis. Genes (Basel). 2021 01 20; 12(2).
    View in: PubMed
    Score: 0.127
  16. Lysyl oxidase directly contributes to extracellular matrix production and fibrosis in systemic sclerosis. Am J Physiol Lung Cell Mol Physiol. 2021 01 01; 320(1):L29-L40.
    View in: PubMed
    Score: 0.124
  17. CD70 Activation Decreases Pulmonary Fibroblast Production of Extracellular Matrix Proteins. Am J Respir Cell Mol Biol. 2020 08; 63(2):255-265.
    View in: PubMed
    Score: 0.123
  18. Long non-coding RNA HOTAIR drives EZH2-dependent myofibroblast activation in systemic sclerosis through miRNA 34a-dependent activation of NOTCH. Ann Rheum Dis. 2020 04; 79(4):507-517.
    View in: PubMed
    Score: 0.119
  19. Periostin plays a critical role in the cell cycle in lung fibroblasts. Respir Res. 2020 Jan 30; 21(1):38.
    View in: PubMed
    Score: 0.118
  20. Identification of multiple, differentially expressed messenger RNAs in dermal fibroblasts from patients with systemic sclerosis. Arthritis Rheum. 1999 Jul; 42(7):1451-7.
    View in: PubMed
    Score: 0.114
  21. Intracellular Heat Shock Protein 70 Deficiency in Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2019 06; 60(6):629-636.
    View in: PubMed
    Score: 0.113
  22. Long intergenic non-coding RNAs regulate human lung fibroblast function: Implications for idiopathic pulmonary fibrosis. Sci Rep. 2019 04 15; 9(1):6020.
    View in: PubMed
    Score: 0.112
  23. NADPH oxidase-mediated induction of reactive oxygen species and extracellular matrix deposition by insulin-like growth factor binding protein-5. Am J Physiol Lung Cell Mol Physiol. 2019 04 01; 316(4):L644-L655.
    View in: PubMed
    Score: 0.111
  24. Long Non-coding RNAs Are Central Regulators of the IL-1?-Induced Inflammatory Response in Normal and Idiopathic Pulmonary Lung Fibroblasts. Front Immunol. 2018; 9:2906.
    View in: PubMed
    Score: 0.109
  25. Pro-fibrotic phenotype of human skin fibroblasts induced by periostin via modulating TGF-? signaling. J Dermatol Sci. 2018 May; 90(2):199-208.
    View in: PubMed
    Score: 0.103
  26. Extracellular Mitochondrial DNA Is Generated by Fibroblasts and Predicts Death in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2017 12 15; 196(12):1571-1581.
    View in: PubMed
    Score: 0.102
  27. Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease. PLoS One. 2017; 12(9):e0184039.
    View in: PubMed
    Score: 0.100
  28. Lysocardiolipin acyltransferase regulates TGF-? mediated lung fibroblast differentiation. Free Radic Biol Med. 2017 11; 112:162-173.
    View in: PubMed
    Score: 0.099
  29. Tenascin-C drives persistence of organ fibrosis. Nat Commun. 2016 06 03; 7:11703.
    View in: PubMed
    Score: 0.092
  30. Fibrogenic Lung Injury Induces Non-Cell-Autonomous Fibroblast Invasion. Am J Respir Cell Mol Biol. 2016 06; 54(6):831-42.
    View in: PubMed
    Score: 0.092
  31. Effect of culture conditions on microRNA expression in primary adult control and COPD lung fibroblasts in vitro. In Vitro Cell Dev Biol Anim. 2015 Apr; 51(4):390-9.
    View in: PubMed
    Score: 0.083
  32. Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis. Am J Physiol Lung Cell Mol Physiol. 2015 Feb 15; 308(4):L344-57.
    View in: PubMed
    Score: 0.083
  33. Fibroblasts that resist cigarette smoke-induced senescence acquire profibrotic phenotypes. Am J Physiol Lung Cell Mol Physiol. 2014 Sep 01; 307(5):L364-73.
    View in: PubMed
    Score: 0.081
  34. Control of IL-6 expression and response in fibroblasts from patients with systemic sclerosis. Autoimmunity. 1994; 17(4):309-18.
    View in: PubMed
    Score: 0.078
  35. Vitamin D modulates prostaglandin E2 synthesis and degradation in human lung fibroblasts. Am J Respir Cell Mol Biol. 2014 Jan; 50(1):40-50.
    View in: PubMed
    Score: 0.078
  36. Telomerase and telomere length in pulmonary fibrosis. Am J Respir Cell Mol Biol. 2013 Aug; 49(2):260-8.
    View in: PubMed
    Score: 0.075
  37. Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis. Arthritis Res Ther. 2013 Jan 10; 15(1):R10.
    View in: PubMed
    Score: 0.073
  38. Interleukin-13-producing CD8+ T cells mediate dermal fibrosis in patients with systemic sclerosis. Arthritis Rheum. 2013 Jan; 65(1):236-46.
    View in: PubMed
    Score: 0.073
  39. Role of endostatin in fibroproliferative disorders.-as a candidate for anti-fibrosis therapy-. Nihon Rinsho Meneki Gakkai Kaishi. 2013; 36(6):452-8.
    View in: PubMed
    Score: 0.073
  40. Mechanisms of pathogenesis in scleroderma. I. Overproduction of interleukin 6 by fibroblasts cultured from affected skin sites of patients with scleroderma. J Rheumatol. 1992 Aug; 19(8):1207-11.
    View in: PubMed
    Score: 0.070
  41. Mechanisms of pathogenesis in scleroderma. II. Effects of serum and conditioned culture medium on fibroblast function in scleroderma. J Rheumatol. 1992 Aug; 19(8):1212-9.
    View in: PubMed
    Score: 0.070
  42. Human recombinant interleukin-4 induces proliferation and interleukin-6 production by cultured human skin fibroblasts. Clin Immunol Immunopathol. 1992 May; 63(2):182-7.
    View in: PubMed
    Score: 0.069
  43. Localized expression of tenascin in systemic sclerosis-associated pulmonary fibrosis and its regulation by insulin-like growth factor binding protein 3. Arthritis Rheum. 2012 Jan; 64(1):272-80.
    View in: PubMed
    Score: 0.068
  44. Decreased caveolin-1 levels contribute to fibrosis and deposition of extracellular IGFBP-5. J Cell Mol Med. 2011 Apr; 15(4):957-69.
    View in: PubMed
    Score: 0.064
  45. Lung tissues in patients with systemic sclerosis have gene expression patterns unique to pulmonary fibrosis and pulmonary hypertension. Arthritis Rheum. 2011 Mar; 63(3):783-94.
    View in: PubMed
    Score: 0.064
  46. PPAR? downregulation by TGF? in fibroblast and impaired expression and function in systemic sclerosis: a novel mechanism for progressive fibrogenesis. PLoS One. 2010 Nov 02; 5(11):e13778.
    View in: PubMed
    Score: 0.062
  47. WNT5A is a regulator of fibroblast proliferation and resistance to apoptosis. Am J Respir Cell Mol Biol. 2009 Nov; 41(5):583-9.
    View in: PubMed
    Score: 0.056
  48. Insulin-like growth factor-II is increased in systemic sclerosis-associated pulmonary fibrosis and contributes to the fibrotic process via Jun N-terminal kinase- and phosphatidylinositol-3 kinase-dependent pathways. Am J Pathol. 2008 Jun; 172(6):1580-90.
    View in: PubMed
    Score: 0.053
  49. Impairment of the antifibrotic effect of hepatocyte growth factor in lung fibroblasts from African Americans: possible role in systemic sclerosis. Arthritis Rheum. 2007 Jul; 56(7):2432-42.
    View in: PubMed
    Score: 0.049
  50. Hepatocyte growth factor and other fibroblast secretions modulate the phenotype of human bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2007 Jun; 292(6):L1352-60.
    View in: PubMed
    Score: 0.048
  51. Cigarette smoke stimulates matrix metalloproteinase-2 activity via EGR-1 in human lung fibroblasts. Am J Respir Cell Mol Biol. 2007 Apr; 36(4):480-90.
    View in: PubMed
    Score: 0.047
  52. Insulin-like growth factor-binding protein-5 induces pulmonary fibrosis and triggers mononuclear cellular infiltration. Am J Pathol. 2006 Nov; 169(5):1633-42.
    View in: PubMed
    Score: 0.047
  53. Insulin-like growth factor binding proteins 3 and 5 are overexpressed in idiopathic pulmonary fibrosis and contribute to extracellular matrix deposition. Am J Pathol. 2005 Feb; 166(2):399-407.
    View in: PubMed
    Score: 0.042
  54. Distinct PKC isoforms mediate cell survival and DNA synthesis in thrombin-induced myofibroblasts. Am J Physiol Lung Cell Mol Physiol. 2005 Jan; 288(1):L190-201.
    View in: PubMed
    Score: 0.041
  55. Systemic sclerosis (scleroderma): specific autoantigen genes are selectively overexpressed in scleroderma fibroblasts. J Immunol. 2001 Dec 15; 167(12):7126-33.
    View in: PubMed
    Score: 0.034
  56. Elevated Fibronectin Levels in Profibrotic CD14+ Monocytes and CD14+ Macrophages in Systemic Sclerosis. Front Immunol. 2021; 12:642891.
    View in: PubMed
    Score: 0.033
  57. Cross-Talk between Transforming Growth Factor-? and Periostin Can Be Targeted for Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2020 02; 62(2):204-216.
    View in: PubMed
    Score: 0.030
  58. Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis. Sci Adv. 2019 07; 5(7):eaav3270.
    View in: PubMed
    Score: 0.029
  59. Characterization of human PDGFR-?-positive pericytes from IPF and non-IPF lungs. Am J Physiol Lung Cell Mol Physiol. 2018 12 01; 315(6):L991-L1002.
    View in: PubMed
    Score: 0.027
  60. RNAi screening identifies a mechanosensitive ROCK-JAK2-STAT3 network central to myofibroblast activation. J Cell Sci. 2018 05 15; 131(10).
    View in: PubMed
    Score: 0.026
  61. Mir-155 is overexpressed in systemic sclerosis fibroblasts and is required for NLRP3 inflammasome-mediated collagen synthesis during fibrosis. Arthritis Res Ther. 2017 06 17; 19(1):144.
    View in: PubMed
    Score: 0.025
  62. Sirtuin 3 Deregulation Promotes Pulmonary Fibrosis. J Gerontol A Biol Sci Med Sci. 2017 May 01; 72(5):595-602.
    View in: PubMed
    Score: 0.024
  63. The role of microRNA-155/liver X receptor pathway in experimental and idiopathic pulmonary fibrosis. J Allergy Clin Immunol. 2017 Jun; 139(6):1946-1956.
    View in: PubMed
    Score: 0.024
  64. Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice. J Biol Chem. 2016 Apr 08; 291(15):8070-89.
    View in: PubMed
    Score: 0.022
  65. Sphingosine-1-phosphate lyase is an endogenous suppressor of pulmonary fibrosis: role of S1P signalling and autophagy. Thorax. 2015 Dec; 70(12):1138-48.
    View in: PubMed
    Score: 0.022
  66. A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis. FASEB J. 2014 Jul; 28(7):3183-96.
    View in: PubMed
    Score: 0.020
  67. Overexpression of c-Met and CD44v6 receptors contributes to autocrine TGF-?1 signaling in interstitial lung disease. J Biol Chem. 2014 Mar 14; 289(11):7856-72.
    View in: PubMed
    Score: 0.019
  68. Phosphodiesterase-4 inhibition augments human lung fibroblast vascular endothelial growth factor production induced by prostaglandin E2. Am J Respir Cell Mol Biol. 2013 Oct; 49(4):571-81.
    View in: PubMed
    Score: 0.019
  69. Expression of c-myc, c-myb, and c-sis in fibroblasts from affected and unaffected skin of patients with systemic sclerosis. Autoimmunity. 1993; 16(3):167-71.
    View in: PubMed
    Score: 0.018
  70. Toll-like receptor 4 signaling augments transforming growth factor-? responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma. Am J Pathol. 2013 Jan; 182(1):192-205.
    View in: PubMed
    Score: 0.018
  71. Early growth response transcription factors: key mediators of fibrosis and novel targets for anti-fibrotic therapy. Matrix Biol. 2011 May; 30(4):235-42.
    View in: PubMed
    Score: 0.016
  72. Nuclear ?-catenin is increased in systemic sclerosis pulmonary fibrosis and promotes lung fibroblast migration and proliferation. Am J Respir Cell Mol Biol. 2011 Nov; 45(5):915-22.
    View in: PubMed
    Score: 0.016
  73. Defective histone acetylation is responsible for the diminished expression of cyclooxygenase 2 in idiopathic pulmonary fibrosis. Mol Cell Biol. 2009 Aug; 29(15):4325-39.
    View in: PubMed
    Score: 0.014
  74. Smad-independent transforming growth factor-beta regulation of early growth response-1 and sustained expression in fibrosis: implications for scleroderma. Am J Pathol. 2008 Oct; 173(4):1085-99.
    View in: PubMed
    Score: 0.013
  75. MAPK pathway mediates EGR-1-HSP70-dependent cigarette smoke-induced chemokine production. Am J Physiol Lung Cell Mol Physiol. 2007 May; 292(5):L1297-303.
    View in: PubMed
    Score: 0.012
  76. Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis. J Exp Med. 2006 Dec 25; 203(13):2895-906.
    View in: PubMed
    Score: 0.012
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.