Connection

Carol Feghali-Bostwick to Scleroderma, Systemic

This is a "connection" page, showing publications Carol Feghali-Bostwick has written about Scleroderma, Systemic.
Connection Strength

13.683
  1. Reduced Cathepsin L expression and secretion into the extracellular milieu contribute to lung fibrosis in systemic sclerosis. Rheumatology (Oxford). 2023 03 01; 62(3):1306-1316.
    View in: PubMed
    Score: 0.629
  2. First Characterization of the Transcriptome of Lung Fibroblasts of SSc Patients and Healthy Donors of African Ancestry. Int J Mol Sci. 2023 Feb 11; 24(4).
    View in: PubMed
    Score: 0.626
  3. The Molecular Mechanisms of Systemic Sclerosis-Associated Lung Fibrosis. Int J Mol Sci. 2023 Feb 03; 24(3).
    View in: PubMed
    Score: 0.625
  4. PDGF Promotes Dermal Fibroblast Activation via a Novel Mechanism Mediated by Signaling Through MCHR1. Front Immunol. 2021; 12:745308.
    View in: PubMed
    Score: 0.576
  5. Antifibrotic factor KLF4 is repressed by the miR-10/TFAP2A/TBX5 axis in dermal fibroblasts: insights from twins discordant for systemic sclerosis. Ann Rheum Dis. 2022 02; 81(2):268-277.
    View in: PubMed
    Score: 0.574
  6. Systemic sclerosis biomarkers detection in the secretome of TGF?1-activated primary human lung fibroblasts. J Proteomics. 2021 06 30; 242:104243.
    View in: PubMed
    Score: 0.553
  7. Elucidating the cellular mechanism for E2-induced dermal fibrosis. Arthritis Res Ther. 2021 02 27; 23(1):68.
    View in: PubMed
    Score: 0.547
  8. Lysyl oxidase directly contributes to extracellular matrix production and fibrosis in systemic sclerosis. Am J Physiol Lung Cell Mol Physiol. 2021 01 01; 320(1):L29-L40.
    View in: PubMed
    Score: 0.532
  9. Integrative analysis of DNA methylation in discordant twins unveils distinct architectures of systemic sclerosis subsets. Clin Epigenetics. 2019 04 04; 11(1):58.
    View in: PubMed
    Score: 0.479
  10. A Human Skin Model Recapitulates Systemic Sclerosis Dermal Fibrosis and Identifies COL22A1 as a TGF? Early Response Gene that Mediates Fibroblast to Myofibroblast Transition. Genes (Basel). 2019 01 22; 10(2).
    View in: PubMed
    Score: 0.473
  11. Optimization of a murine and human tissue model to recapitulate dermal and pulmonary features of systemic sclerosis. PLoS One. 2017; 12(6):e0179917.
    View in: PubMed
    Score: 0.424
  12. Genetics of systemic sclerosis: recent advances. Curr Opin Rheumatol. 2015 Nov; 27(6):521-9.
    View in: PubMed
    Score: 0.378
  13. Anti-RNA Polymerase II Antibodies in a U.S. Cohort of Systemic Sclerosis Patients: Comment on the Article by Hamaguchi et al. Arthritis Rheumatol. 2015 Sep; 67(9):2547-8.
    View in: PubMed
    Score: 0.374
  14. Editorial: molecular insights into systemic sclerosis-associated interstitial lung disease. Arthritis Rheumatol. 2014 Mar; 66(3):485-7.
    View in: PubMed
    Score: 0.337
  15. The membrane-associated adaptor protein DOK5 is upregulated in systemic sclerosis and associated with IGFBP-5-induced fibrosis. PLoS One. 2014; 9(2):e87754.
    View in: PubMed
    Score: 0.336
  16. Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis. Arthritis Res Ther. 2013 Jan 10; 15(1):R10.
    View in: PubMed
    Score: 0.311
  17. Role of endostatin in fibroproliferative disorders.-as a candidate for anti-fibrosis therapy-. Nihon Rinsho Meneki Gakkai Kaishi. 2013; 36(6):452-8.
    View in: PubMed
    Score: 0.311
  18. Antifibrotic effects of roscovitine in normal and scleroderma fibroblasts. PLoS One. 2012; 7(11):e48560.
    View in: PubMed
    Score: 0.308
  19. Localized expression of tenascin in systemic sclerosis-associated pulmonary fibrosis and its regulation by insulin-like growth factor binding protein 3. Arthritis Rheum. 2012 Jan; 64(1):272-80.
    View in: PubMed
    Score: 0.290
  20. Lung tissues in patients with systemic sclerosis have gene expression patterns unique to pulmonary fibrosis and pulmonary hypertension. Arthritis Rheum. 2011 Mar; 63(3):783-94.
    View in: PubMed
    Score: 0.274
  21. Pathogenesis of pulmonary fibrosis in systemic sclerosis: lessons from interstitial lung disease. Curr Rheumatol Rep. 2010 Feb; 12(1):19-25.
    View in: PubMed
    Score: 0.254
  22. Anti-U11/U12 RNP antibodies in systemic sclerosis: a new serologic marker associated with pulmonary fibrosis. Arthritis Rheum. 2009 Jul 15; 61(7):958-65.
    View in: PubMed
    Score: 0.244
  23. Insulin-like growth factor-II is increased in systemic sclerosis-associated pulmonary fibrosis and contributes to the fibrotic process via Jun N-terminal kinase- and phosphatidylinositol-3 kinase-dependent pathways. Am J Pathol. 2008 Jun; 172(6):1580-90.
    View in: PubMed
    Score: 0.225
  24. Monozygotic twins clinically discordant for scleroderma show concordance for fibroblast gene expression profiles. Arthritis Rheum. 2005 Oct; 52(10):3305-14.
    View in: PubMed
    Score: 0.188
  25. Genetics and proteomics in scleroderma. Curr Rheumatol Rep. 2005 Apr; 7(2):129-34.
    View in: PubMed
    Score: 0.182
  26. Analysis of systemic sclerosis in twins reveals low concordance for disease and high concordance for the presence of antinuclear antibodies. Arthritis Rheum. 2003 Jul; 48(7):1956-63.
    View in: PubMed
    Score: 0.161
  27. Elevated Fibronectin Levels in Profibrotic CD14+ Monocytes and CD14+ Macrophages in Systemic Sclerosis. Front Immunol. 2021; 12:642891.
    View in: PubMed
    Score: 0.141
  28. Exercise as a multi-modal disease-modifying medicine in systemic sclerosis: An introduction by The Global Fellowship on Rehabilitation and Exercise in Systemic Sclerosis (G-FoRSS). Best Pract Res Clin Rheumatol. 2021 09; 35(3):101695.
    View in: PubMed
    Score: 0.140
  29. Differential DNA Methylation Landscape in Skin Fibroblasts from African Americans with Systemic Sclerosis. Genes (Basel). 2021 01 20; 12(2).
    View in: PubMed
    Score: 0.136
  30. Prediction of severity and subtype of fibrosing disease using model informed by inflammation and extracellular matrix gene index. PLoS One. 2020; 15(10):e0240986.
    View in: PubMed
    Score: 0.133
  31. Long non-coding RNA HOTAIR drives EZH2-dependent myofibroblast activation in systemic sclerosis through miRNA 34a-dependent activation of NOTCH. Ann Rheum Dis. 2020 04; 79(4):507-517.
    View in: PubMed
    Score: 0.127
  32. Identification of multiple, differentially expressed messenger RNAs in dermal fibroblasts from patients with systemic sclerosis. Arthritis Rheum. 1999 Jul; 42(7):1451-7.
    View in: PubMed
    Score: 0.122
  33. NADPH oxidase-mediated induction of reactive oxygen species and extracellular matrix deposition by insulin-like growth factor binding protein-5. Am J Physiol Lung Cell Mol Physiol. 2019 04 01; 316(4):L644-L655.
    View in: PubMed
    Score: 0.119
  34. Novel classification for global gene signature model for predicting severity of systemic sclerosis. PLoS One. 2018; 13(6):e0199314.
    View in: PubMed
    Score: 0.113
  35. Mir-155 is overexpressed in systemic sclerosis fibroblasts and is required for NLRP3 inflammasome-mediated collagen synthesis during fibrosis. Arthritis Res Ther. 2017 06 17; 19(1):144.
    View in: PubMed
    Score: 0.106
  36. Differences in Right Ventricular Functional Changes during Treatment between Systemic Sclerosis-associated Pulmonary Arterial Hypertension and Idiopathic Pulmonary Arterial Hypertension. Ann Am Thorac Soc. 2017 May; 14(5):682-689.
    View in: PubMed
    Score: 0.105
  37. Review: Frontiers of Antifibrotic Therapy in Systemic Sclerosis. Arthritis Rheumatol. 2017 02; 69(2):257-267.
    View in: PubMed
    Score: 0.103
  38. miR-155 in the progression of lung fibrosis in systemic sclerosis. Arthritis Res Ther. 2016 07 05; 18(1):155.
    View in: PubMed
    Score: 0.099
  39. Tenascin-C drives persistence of organ fibrosis. Nat Commun. 2016 06 03; 7:11703.
    View in: PubMed
    Score: 0.098
  40. Netrin-1 Regulates Fibrocyte Accumulation in the Decellularized Fibrotic Sclerodermatous Lung Microenvironment and in Bleomycin-Induced Pulmonary Fibrosis. Arthritis Rheumatol. 2016 05; 68(5):1251-61.
    View in: PubMed
    Score: 0.098
  41. Endothelial Cells Expressing Endothelial and Mesenchymal Cell Gene Products in Lung Tissue From Patients With Systemic Sclerosis-Associated Interstitial Lung Disease. Arthritis Rheumatol. 2016 Jan; 68(1):210-7.
    View in: PubMed
    Score: 0.096
  42. Update on scleroderma-associated interstitial lung disease. Curr Opin Rheumatol. 2014 Nov; 26(6):630-6.
    View in: PubMed
    Score: 0.088
  43. Review: interstitial lung disease associated with systemic sclerosis and idiopathic pulmonary fibrosis: how similar and distinct? Arthritis Rheumatol. 2014 Aug; 66(8):1967-78.
    View in: PubMed
    Score: 0.087
  44. Control of IL-6 expression and response in fibroblasts from patients with systemic sclerosis. Autoimmunity. 1994; 17(4):309-18.
    View in: PubMed
    Score: 0.083
  45. Skin gene expression correlates of severity of interstitial lung disease in systemic sclerosis. Arthritis Rheum. 2013 Nov; 65(11):2917-27.
    View in: PubMed
    Score: 0.082
  46. Expression of c-myc, c-myb, and c-sis in fibroblasts from affected and unaffected skin of patients with systemic sclerosis. Autoimmunity. 1993; 16(3):167-71.
    View in: PubMed
    Score: 0.078
  47. Interleukin-13-producing CD8+ T cells mediate dermal fibrosis in patients with systemic sclerosis. Arthritis Rheum. 2013 Jan; 65(1):236-46.
    View in: PubMed
    Score: 0.078
  48. Toll-like receptor 4 signaling augments transforming growth factor-? responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma. Am J Pathol. 2013 Jan; 182(1):192-205.
    View in: PubMed
    Score: 0.077
  49. X chromosome gene methylation in peripheral lymphocytes from monozygotic twins discordant for scleroderma. Clin Exp Immunol. 2012 Sep; 169(3):253-62.
    View in: PubMed
    Score: 0.076
  50. Mechanisms of pathogenesis in scleroderma. I. Overproduction of interleukin 6 by fibroblasts cultured from affected skin sites of patients with scleroderma. J Rheumatol. 1992 Aug; 19(8):1207-11.
    View in: PubMed
    Score: 0.075
  51. Mechanisms of pathogenesis in scleroderma. II. Effects of serum and conditioned culture medium on fibroblast function in scleroderma. J Rheumatol. 1992 Aug; 19(8):1212-9.
    View in: PubMed
    Score: 0.075
  52. Chitinase 1 is a biomarker for and therapeutic target in scleroderma-associated interstitial lung disease that augments TGF-?1 signaling. J Immunol. 2012 Sep 01; 189(5):2635-44.
    View in: PubMed
    Score: 0.075
  53. The inflammasome activating caspase 1 mediates fibrosis and myofibroblast differentiation in systemic sclerosis. Arthritis Rheum. 2011 Nov; 63(11):3563-74.
    View in: PubMed
    Score: 0.072
  54. Serum antibody to retroviral gag proteins in systemic sclerosis. Arthritis Rheum. 1991 Oct; 34(10):1336-7.
    View in: PubMed
    Score: 0.071
  55. The early growth response gene Egr2 (Alias Krox20) is a novel transcriptional target of transforming growth factor-? that is up-regulated in systemic sclerosis and mediates profibrotic responses. Am J Pathol. 2011 May; 178(5):2077-90.
    View in: PubMed
    Score: 0.069
  56. Nuclear ?-catenin is increased in systemic sclerosis pulmonary fibrosis and promotes lung fibroblast migration and proliferation. Am J Respir Cell Mol Biol. 2011 Nov; 45(5):915-22.
    View in: PubMed
    Score: 0.069
  57. PPAR? downregulation by TGF? in fibroblast and impaired expression and function in systemic sclerosis: a novel mechanism for progressive fibrogenesis. PLoS One. 2010 Nov 02; 5(11):e13778.
    View in: PubMed
    Score: 0.067
  58. Smad-independent transforming growth factor-beta regulation of early growth response-1 and sustained expression in fibrosis: implications for scleroderma. Am J Pathol. 2008 Oct; 173(4):1085-99.
    View in: PubMed
    Score: 0.058
  59. B cell infiltration in systemic sclerosis-associated interstitial lung disease. Arthritis Rheum. 2007 Sep; 56(9):3167-8.
    View in: PubMed
    Score: 0.054
  60. Impairment of the antifibrotic effect of hepatocyte growth factor in lung fibroblasts from African Americans: possible role in systemic sclerosis. Arthritis Rheum. 2007 Jul; 56(7):2432-42.
    View in: PubMed
    Score: 0.053
  61. Pulmonary involvement in systemic sclerosis: associations with genetic, serologic, sociodemographic, and behavioral factors. Arthritis Rheum. 2007 Mar 15; 57(2):318-26.
    View in: PubMed
    Score: 0.052
  62. Reflux and autoimmunity: common links among patients with pulmonary fibrosis? Chest. 2007 Mar; 131(3):940-941.
    View in: PubMed
    Score: 0.052
  63. Unique characteristics of systemic sclerosis sine scleroderma-associated interstitial lung disease. Chest. 2006 Oct; 130(4):976-81.
    View in: PubMed
    Score: 0.050
  64. Distinct PKC isoforms mediate cell survival and DNA synthesis in thrombin-induced myofibroblasts. Am J Physiol Lung Cell Mol Physiol. 2005 Jan; 288(1):L190-201.
    View in: PubMed
    Score: 0.044
  65. Systemic sclerosis (scleroderma): specific autoantigen genes are selectively overexpressed in scleroderma fibroblasts. J Immunol. 2001 Dec 15; 167(12):7126-33.
    View in: PubMed
    Score: 0.036
  66. Autoreactive T cells to topoisomerase I in monozygotic twins discordant for systemic sclerosis. Arthritis Rheum. 2001 Jul; 44(7):1654-9.
    View in: PubMed
    Score: 0.035
  67. Pro-fibrotic phenotype of human skin fibroblasts induced by periostin via modulating TGF-? signaling. J Dermatol Sci. 2018 May; 90(2):199-208.
    View in: PubMed
    Score: 0.028
  68. Endothelial GATA-6 deficiency promotes pulmonary arterial hypertension. Am J Pathol. 2013 Jun; 182(6):2391-406.
    View in: PubMed
    Score: 0.020
  69. Early growth response transcription factors: key mediators of fibrosis and novel targets for anti-fibrotic therapy. Matrix Biol. 2011 May; 30(4):235-42.
    View in: PubMed
    Score: 0.017
  70. Partial inhibition of integrin alpha(v)beta6 prevents pulmonary fibrosis without exacerbating inflammation. Am J Respir Crit Care Med. 2008 Jan 01; 177(1):56-65.
    View in: PubMed
    Score: 0.014
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.