Amino Acid Chloromethyl Ketones
"Amino Acid Chloromethyl Ketones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Inhibitors of SERINE ENDOPEPTIDASES and sulfhydryl group-containing enzymes. They act as alkylating agents and are known to interfere in the translation process.
| Descriptor ID |
D000590
|
| MeSH Number(s) |
D12.125.065
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Amino Acid Chloromethyl Ketones".
Below are MeSH descriptors whose meaning is more specific than "Amino Acid Chloromethyl Ketones".
This graph shows the total number of publications written about "Amino Acid Chloromethyl Ketones" by people in this website by year, and whether "Amino Acid Chloromethyl Ketones" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Amino Acid Chloromethyl Ketones" by people in Profiles.
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Survival or death: a dual role for autophagy in stress-induced pericyte loss in diabetic retinopathy. Diabetologia. 2016 10; 59(10):2251-61.
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Increased killing of SCCVII squamous cell carcinoma cells after the combination of Pc 4 photodynamic therapy and dasatinib is associated with enhanced caspase-3 activity and ceramide synthase 1 upregulation. Int J Oncol. 2013 Dec; 43(6):2064-72.
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Development of pancreas storage solutions: Initial screening of cytoprotective supplements for ?-cell survival and metabolic status after hypothermic storage. Biopreserv Biobank. 2013 Feb; 11(1):12-8.
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Mitochondrially targeted ceramides preferentially promote autophagy, retard cell growth, and induce apoptosis. J Lipid Res. 2011 Feb; 52(2):278-88.
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Docetaxel-induced prostate cancer cell death involves concomitant activation of caspase and lysosomal pathways and is attenuated by LEDGF/p75. Mol Cancer. 2009 Aug 28; 8:68.
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In vivo administration of calpeptin attenuates calpain activation and cardiomyocyte loss in pressure-overloaded feline myocardium. Am J Physiol Heart Circ Physiol. 2008 Jul; 295(1):H314-26.
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Apoptosis and autophagy in photoreceptors exposed to oxidative stress. Autophagy. 2007 Sep-Oct; 3(5):433-41.
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Crystal structure of Escherichia coli penicillin-binding protein 5 bound to a tripeptide boronic acid inhibitor: a role for Ser-110 in deacylation. Biochemistry. 2005 Jun 14; 44(23):8207-17.
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Myocyte contractility with caspase inhibition and simulated hyperkalemic cardioplegic arrest. Ann Thorac Surg. 2004 May; 77(5):1684-9; discussion 1689-90.
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A novel tumor suppressor protein promotes keratinocyte terminal differentiation via activation of type I transglutaminase. J Biol Chem. 2003 Nov 28; 278(48):48066-73.