"Occludin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A MARVEL domain protein that binds to and regulates PROTEIN PHOSPHATASE 1. Occludin plays an important role in the formation and regulation of the TIGHT JUNCTION paracellular permeability barrier.
Descriptor ID |
D062793
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MeSH Number(s) |
D12.776.543.488.500 D12.776.543.940.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Occludin".
Below are MeSH descriptors whose meaning is more specific than "Occludin".
This graph shows the total number of publications written about "Occludin" by people in this website by year, and whether "Occludin" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 |
2003 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Occludin" by people in Profiles.
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Progesterone decreases gut permeability through upregulating occludin expression in primary human gut tissues and Caco-2 cells. Sci Rep. 2019 06 10; 9(1):8367.
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Vascular changes in rat hippocampus following a high saturated fat and cholesterol diet. J Cereb Blood Flow Metab. 2012 Apr; 32(4):643-53.
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Expression of kinase-inactive c-Src delays oxidative stress-induced disassembly and accelerates calcium-mediated reassembly of tight junctions in the Caco-2 cell monolayer. J Biol Chem. 2003 Apr 04; 278(14):11916-24.
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Tyrosine phosphorylation and dissociation of occludin-ZO-1 and E-cadherin-beta-catenin complexes from the cytoskeleton by oxidative stress. Biochem J. 2002 12 01; 368(Pt 2):471-81.