"Trefoil Factor-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 106 amino acid (12 kDa) trefoil factor that contains two trefoil domains and associates with MUCIN-6. It is expressed in the GASTROINTESTINAL TRACT by cells of BRUNNER GLANDS; PYLORIC GLANDS and mucous neck cells. It inhibits GASTROINTESTINAL MOTILITY and GASTRIC ACID secretion and may help maintain the structural integrity of gastric mucus.
| Descriptor ID |
D000071164
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| MeSH Number(s) |
D12.644.937.750
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Trefoil Factor-2".
Below are MeSH descriptors whose meaning is more specific than "Trefoil Factor-2".
This graph shows the total number of publications written about "Trefoil Factor-2" by people in this website by year, and whether "Trefoil Factor-2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Trefoil Factor-2" by people in Profiles.
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Trefoil factor 2 secreted from damaged hepatocytes activates hepatic stellate cells to induce fibrogenesis. J Biol Chem. 2021 07; 297(1):100887.