"Glutathione Reductase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Catalyzes the oxidation of GLUTATHIONE to GLUTATHIONE DISULFIDE in the presence of NADP+. Deficiency in the enzyme is associated with HEMOLYTIC ANEMIA. Formerly listed as EC 1.6.4.2.
| Descriptor ID |
D005980
|
| MeSH Number(s) |
D08.811.682.667.092
|
| Concept/Terms |
Glutathione Reductase- Glutathione Reductase
- Reductase, Glutathione
- Glutathione-Disulfide Reductase
- Reductase, Glutathione-Disulfide
|
Below are MeSH descriptors whose meaning is more general than "Glutathione Reductase".
Below are MeSH descriptors whose meaning is more specific than "Glutathione Reductase".
This graph shows the total number of publications written about "Glutathione Reductase" by people in this website by year, and whether "Glutathione Reductase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glutathione Reductase" by people in Profiles.
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Endostatin inhibits androgen-independent prostate cancer growth by suppressing nuclear receptor-mediated oxidative stress. FASEB J. 2017 04; 31(4):1608-1619.
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Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry. J Rheumatol. 2013 Jun; 40(6):842-9.
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Preclinical pharmacokinetic analysis of NOV-002, a glutathione disulfide mimetic. Biomed Pharmacother. 2010 Sep; 64(7):493-8.
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Novel alkylpolyaminoguanidines and alkylpolyaminobiguanides with potent antitrypanosomal activity. Bioorg Med Chem Lett. 2006 Jun 15; 16(12):3229-32.
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Studies on hepatic injury and antioxidant enzyme activities in rat subcellular organelles following in vivo ischemia and reperfusion. Mol Cell Biochem. 1997 Nov; 176(1-2):337-47.
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Susceptibility to hepatic oxidative stress in rabbits fed different animal and plant fats. J Am Coll Nutr. 1996 Jun; 15(3):289-94.
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Glutathione, glutathione S-transferases, and related redox enzymes in Adriamycin-resistant cell lines with a multidrug resistant phenotype. Cancer Commun. 1989; 1(2):133-9.
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Activation of the lipoxygenase pathway in the methionine enkephalin induced respiratory burst in human polymorphonuclear leukocytes. Life Sci. 1988; 42(22):2299-306.
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Carbamoylation of glutathione reductase and changes in cellular and chromosome morphology in a rat cell line resistant to nitrogen mustards but collaterally sensitive to nitrosoureas. Cancer Res. 1985 May; 45(5):2326-33.
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Mechanism of action of 2-haloethylnitrosoureas on deoxyribonucleic acid. Pathways of aqueous decomposition and pharmacological characteristics of new anticancer disulfide-linked nitrosoureas. Biochem Pharmacol. 1985 Apr 01; 34(7):1015-24.