"DNA Polymerase II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms. It may be present in higher organisms and has an intrinsic molecular activity only 5% of that of DNA Polymerase I. This polymerase has 3'-5' exonuclease activity, is effective only on duplex DNA with gaps or single-strand ends of less than 100 nucleotides as template, and is inhibited by sulfhydryl reagents. EC 2.7.7.7.
| Descriptor ID |
D004257
|
| MeSH Number(s) |
D08.811.913.696.445.308.300.230
|
| Concept/Terms |
DNA Polymerase II- DNA Polymerase II
- DNA Polymerase epsilon
- DNA-Dependent DNA Polymerase II
- DNA Dependent DNA Polymerase II
- DNA Pol II
|
Below are MeSH descriptors whose meaning is more general than "DNA Polymerase II".
Below are MeSH descriptors whose meaning is more specific than "DNA Polymerase II".
This graph shows the total number of publications written about "DNA Polymerase II" by people in this website by year, and whether "DNA Polymerase II" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 2 | 2 |
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Below are the most recent publications written about "DNA Polymerase II" by people in Profiles.
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An NRG Oncology/GOG study of molecular classification for risk prediction in endometrioid endometrial cancer. Gynecol Oncol. 2018 01; 148(1):174-180.
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Comprehensive Analysis of Hypermutation in Human Cancer. Cell. 2017 Nov 16; 171(5):1042-1056.e10.
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Increased incidence of FBXW7 and POLE proofreading domain mutations in young adult colorectal cancers. Cancer. 2016 09 15; 122(18):2828-35.
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Conformational changes associated with template commitment in ATP-dependent chromatin remodeling by ISW2. Mol Cell. 2009 Jul 10; 35(1):58-69.