"Reserpine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
| Descriptor ID |
D012110
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| MeSH Number(s) |
D03.132.436.681.933.500 D03.633.100.473.402.681.933.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Reserpine".
Below are MeSH descriptors whose meaning is more specific than "Reserpine".
This graph shows the total number of publications written about "Reserpine" by people in this website by year, and whether "Reserpine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
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Below are the most recent publications written about "Reserpine" by people in Profiles.
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Use of nanoporous alumina surface for desorption electrospray ionization mass spectrometry in proteomic analysis. Biomed Microdevices. 2008 Aug; 10(4):531-8.
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Ethanol facilitates glutamatergic transmission to dopamine neurons in the ventral tegmental area. Neuropsychopharmacology. 2009 Jan; 34(2):307-18.
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The partial dopamine D2-like receptor agonist terguride functions as an agonist in preweanling rats after a 5-day reserpine regimen. Psychopharmacology (Berl). 2006 Mar; 185(1):104-11.
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Renal vascular effects of antihypertensive therapy in uninephrectomized SHR. Kidney Int. 1989 Mar; 35(3):790-8.
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C1 area of the rostral ventrolateral medulla as a site for the central hypotensive action of propranolol. J Pharmacol Exp Ther. 1988 Aug; 246(2):529-33.
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Beta 2-adrenergic receptors contribute to catecholamine-stimulated shortening of action potential duration in dog atrial muscle. Proc Natl Acad Sci U S A. 1985 Jul; 82(13):4521-5.
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Colonic glycoprotein secretion and calmodulin-acceptor proteins in the reserpine-treated rat. Am J Physiol. 1985 Jan; 248(1 Pt 1):G54-60.
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Reserpine-induced alterations in mucus production and calmodulin-binding proteins in a human epithelial cell line. Exp Cell Res. 1984 Jan; 150(1):141-51.
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Rigid analogues of dopamine: synthesis and interaction of 6-exo- and 6-endo-(3',4'-dihydroxyphenyl)-2-azabicyclo[2.2.2]octanes with dopamine uptake sites and receptors. J Med Chem. 1982 Mar; 25(3):213-6.
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Biological relationships between mania and melancholia. Encephale. 1982; 8(2):213-28.