"Dysgerminoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A malignant ovarian neoplasm, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. It is the counterpart of the classical seminoma of the testis, to which it is both grossly and histologically identical. Dysgerminomas comprise 16% of all germ cell tumors but are rare before the age of 10, although nearly 50% occur before the age of 20. They are generally considered of low-grade malignancy but may spread if the tumor extends through its capsule and involves lymph nodes or blood vessels. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1646)
| Descriptor ID |
D004407
|
| MeSH Number(s) |
C04.557.465.330.300
|
| Concept/Terms |
Dysgerminoma- Dysgerminoma
- Dysgerminomas
- Disgerminoma
- Disgerminomas
|
Below are MeSH descriptors whose meaning is more general than "Dysgerminoma".
Below are MeSH descriptors whose meaning is more specific than "Dysgerminoma".
This graph shows the total number of publications written about "Dysgerminoma" by people in this website by year, and whether "Dysgerminoma" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
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Below are the most recent publications written about "Dysgerminoma" by people in Profiles.
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The tumor suppressor gene TRC8/RNF139 is disrupted by a constitutional balanced translocation t(8;22)(q24.13;q11.21) in a young girl with dysgerminoma. Mol Cancer. 2009 Jul 30; 8:52.
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Malignant ovarian germ cell tumours -- a survival and prognostic analysis. Acta Oncol. 1999; 38(4):455-60.
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Primary central nervous system germ cell tumors. Effect of histologic confirmation on radiotherapy. Cancer. 1988 Jun 01; 61(11):2148-52.
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Primary malignant mediastinal germ-cell tumors and the contribution of radiotherapy: a southeastern multi-institutional study. Am J Clin Oncol. 1987 Aug; 10(4):302-6.
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A VP16-213- and cisplatin-containing regimen for treatment of refractory ovarian germ cell malignancies. Am J Obstet Gynecol. 1984 Dec 15; 150(8):927-31.
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Effects of serum concentration on some growth characteristics of cultured murine parietal yolk sac carcinoma cells. Tissue Cell. 1982; 14(3):425-34.
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Genital malignancy in pregnancy. Am J Obstet Gynecol. 1977 Nov 01; 129(5):536-42.
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Gonadoblastoma: clinicopathologic correlation in six patients. Am J Obstet Gynecol. 1976 Nov 01; 126(5):579-85.
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Carcinoma of the ovary associated with pregnancy. Obstet Gynecol. 1971 Jul; 38(1):111-6.