"Ephrin-A1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An ephrin that was originally identified as the product of an early response gene induced by TUMOR NECROSIS FACTORS. It is linked to the CELL MEMBRANE via a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR and binds EPHA2 RECEPTOR with high affinity. During embryogenesis high levels of ephrin-A1 are expressed in LUNG; KIDNEY; SALIVARY GLANDS; and INTESTINE.
| Descriptor ID |
D036382
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| MeSH Number(s) |
D12.644.276.500.100 D12.776.395.550.448.300 D12.776.467.500.100 D12.776.543.287.100 D12.776.543.484.500.300 D12.776.543.550.418.300 D23.529.500.100
|
| Concept/Terms |
Ephrin-A1- Ephrin-A1
- Ephrin A1
- Eck Ligand
- Ligand, Eck
- LERK-1 Protein
- LERK 1 Protein
- Endothelium Secreted Protein B61
- Epl1 Protein
- EPLG1
- B61 Secreted Protein, Endothelium
- Eck RPTK Ligand
- RPTK Ligand, Eck
|
Below are MeSH descriptors whose meaning is more general than "Ephrin-A1".
Below are MeSH descriptors whose meaning is more specific than "Ephrin-A1".
This graph shows the total number of publications written about "Ephrin-A1" by people in this website by year, and whether "Ephrin-A1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ephrin-A1" by people in Profiles.
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A plasma membrane microdomain compartmentalizes ephrin-generated cAMP signals to prune developing retinal axon arbors. Nat Commun. 2016 10 03; 7:12896.
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The ephrin A1-EphA2 system promotes cardiac stem cell migration after infarction. Circ Res. 2011 Apr 29; 108(9):1071-83.
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Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis. Mol Cell Biol. 2006 Jul; 26(13):4830-42.