"Receptors, Leptin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface receptors for obesity factor (LEPTIN), a hormone secreted by the WHITE ADIPOCYTES. Upon leptin-receptor interaction, the signal is mediated through the JAK2/STAT3 pathway to regulate food intake, energy balance and fat storage.
| Descriptor ID |
D054411
|
| MeSH Number(s) |
D12.776.543.750.650.500
|
| Concept/Terms |
Receptors, Leptin- Receptors, Leptin
- Leptin-Binding Protein
- Leptin Binding Protein
- Receptor, Leptin
- Leptin Receptor
- Antigens, CD295
- LEPR Protein
- OB Receptor
- Receptor, OB
- CD295 Antigens
- Leptin Receptors
OBRb Receptor- OBRb Receptor
- Receptor, OBRb
- Leptin Receptor, Large Isoform
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Leptin".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Leptin".
This graph shows the total number of publications written about "Receptors, Leptin" by people in this website by year, and whether "Receptors, Leptin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, Leptin" by people in Profiles.
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Linking obesity-induced leptin-signaling pathways to common endocrine-related cancers in women. Endocrine. 2019 01; 63(1):3-17.
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The adipokine leptin mediates muscle- and liver-derived IGF-1 in aged mice. Exp Gerontol. 2015 Oct; 70:92-6.
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Bilirubin increases insulin sensitivity in leptin-receptor deficient and diet-induced obese mice through suppression of ER stress and chronic inflammation. Endocrinology. 2014 Mar; 155(3):818-28.
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Absence of functional leptin receptor isoforms in the POUND (Lepr(db/lb)) mouse is associated with muscle atrophy and altered myoblast proliferation and differentiation. PLoS One. 2013; 8(8):e72330.
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Differential regulation of adiponectin receptor gene expression by adiponectin and leptin in myotubes derived from obese and diabetic individuals. Obesity (Silver Spring). 2006 Nov; 14(11):1898-904.
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Leptin in hepatic fibrosis: evidence for increased collagen production in stellate cells and lean littermates of ob/ob mice. Hepatology. 2002 Apr; 35(4):762-71.