"Ornithine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An amino acid produced in the urea cycle by the splitting off of urea from arginine.
| Descriptor ID |
D009952
|
| MeSH Number(s) |
D12.125.068.665 D12.125.095.765
|
| Concept/Terms |
Ornithine- Ornithine
- Ornithine, (L)-Isomer
- 2,5-Diaminopentanoic Acid
- 2,5 Diaminopentanoic Acid
|
Below are MeSH descriptors whose meaning is more general than "Ornithine".
Below are MeSH descriptors whose meaning is more specific than "Ornithine".
This graph shows the total number of publications written about "Ornithine" by people in this website by year, and whether "Ornithine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 2 | 0 | 2 |
| 2015 | 2 | 2 | 4 |
| 2018 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ornithine" by people in Profiles.
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Alterations in bone metabolites with age in C57BL/6 mice model. Biogerontology. 2022 10; 23(5):629-640.
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Safety, tolerability, and pharmacokinetics of l-ornithine phenylacetate in patients with acute liver injury/failure and hyperammonemia. Hepatology. 2018 03; 67(3):1003-1013.
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Molecular targeting of protein arginine deiminases to suppress colitis and prevent colon cancer. Oncotarget. 2015 Nov 03; 6(34):36053-62.
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Novel Ammonia-Lowering Agents for Hepatic Encephalopathy. Clin Liver Dis. 2015 Aug; 19(3):539-49.
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Inhibiting protein arginine deiminases has antioxidant consequences. J Pharmacol Exp Ther. 2015 Apr; 353(1):64-70.
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Protein Arginine Deiminases and Associated Citrullination: Physiological Functions and Diseases Associated with Dysregulation. Curr Drug Targets. 2015; 16(7):700-10.
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The development of N-a-(2-carboxyl)benzoyl-N(5)-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-F-amidine) and N-a-(2-carboxyl)benzoyl-N(5)-(2-chloro-1-iminoethyl)-l-ornithine amide (o-Cl-amidine) as second generation protein arginine deiminase (PAD) inhibitors. J Med Chem. 2011 Oct 13; 54(19):6919-35.
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Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor. Am J Physiol Gastrointest Liver Physiol. 2011 Jun; 300(6):G929-38.
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A neonatal screening test for argininosuccinic acid lyase deficiency and other urea cycle disorders. Pediatrics. 1982 Oct; 70(4):526-31.