"Inteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The internal fragments of precursor proteins (INternal proTEINS) that are autocatalytically removed by PROTEIN SPLICING. The flanking fragments (EXTEINS) are ligated forming mature proteins. The nucleic acid sequences coding for inteins are considered to be MOBILE GENETIC ELEMENTS. Inteins are composed of self-splicing domains and an endonuclease domain which plays a role in the spread of the intein's genomic sequence. Mini-inteins are composed of the self-splicing domains only.
| Descriptor ID |
D047668
|
| MeSH Number(s) |
G02.111.570.060.440
|
| Concept/Terms |
Inteins- Inteins
- Intein
- Protein Introns
- Intervening Protein Sequence
- Intervening Protein Sequences
- Protein Sequence, Intervening
- Protein Sequences, Intervening
- Sequence, Intervening Protein
- Sequences, Intervening Protein
- Introns, Protein
- Intron, Protein
- Protein Intron
|
Below are MeSH descriptors whose meaning is more general than "Inteins".
Below are MeSH descriptors whose meaning is more specific than "Inteins".
This graph shows the total number of publications written about "Inteins" by people in this website by year, and whether "Inteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
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Below are the most recent publications written about "Inteins" by people in Profiles.
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Intein-mediated protein purification of fusion proteins expressed under high-cell density conditions in E. coli. J Biotechnol. 2006 Aug 20; 125(1):48-56.
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Simulation of large-scale production of a soluble recombinant protein expressed in Escherichia coli using an intein-mediated purification system. Appl Biochem Biotechnol. 2005 Aug; 126(2):93-118.